System and mandrel for creating graft devices
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61F-002/04
A61F-002/06
B05B-013/00
B05B-013/04
B05B-013/06
A61B-017/00
출원번호
US-0984249
(2012-02-08)
등록번호
US-9867690
(2018-01-16)
국제출원번호
PCT/US2012/024251
(2012-02-08)
§371/§102 date
20131114
(20131114)
국제공개번호
WO2012/109309
(2012-08-16)
발명자
/ 주소
Soletti, Lorenzo
El-Kurdi, Mohammed S.
McGrath, Jon
Flaherty, J. Christopher
Vu, Liem
Brightbill, Jerry
Evans, Stephen
Ting, Joseph
Rezac, David
Robinson, Timothy
출원인 / 주소
NEOGRAFT TECHNOLOGIES, INC.
대리인 / 주소
Wilson Sonsini Goodrich & Rosati
인용정보
피인용 횟수 :
0인용 특허 :
15
초록
A system for applying a fiber matrix on a tubular member is provided. A mandrel, configured for atraumatic placement within the tubular member, is included. Methods for atraumatic placement of a mandrel into a tubular member are also provided.
대표청구항▼
1. A system for applying a fiber matrix on a tubular member, the system comprising: (a) a fiber matrix delivery assembly;(b) a tubular member; and(c) a mandrel comprising a porous portion, a mandrel first end and a mandrel second end, (i) wherein the mandrel is constructed and arranged to be atrauma
1. A system for applying a fiber matrix on a tubular member, the system comprising: (a) a fiber matrix delivery assembly;(b) a tubular member; and(c) a mandrel comprising a porous portion, a mandrel first end and a mandrel second end, (i) wherein the mandrel is constructed and arranged to be atraumatically inserted into the tubular member, radially expanded within the tubular member, and attached to the fiber matrix delivery assembly, and(ii) wherein the mandrel comprises a braided construction, a helical construction, a guidewire attached to the mandrel first end, or any combination thereof. 2. The system of claim 1, wherein the mandrel further comprises a lumen. 3. The system of claim 1, wherein the system is constructed and arranged to deliver fluid from the porous portion of the mandrel to the tubular member. 4. The system of claim 1, wherein the mandrel comprises: a middle portion, and at least one of the mandrel first end or the mandrel second end comprises a smaller diameter than a diameter of the middle portion. 5. The system of claim 1, wherein the mandrel comprises a compressible tube constructed and arranged to radially expand when compressed. 6. The system of claim 1, wherein the mandrel is constructed and arranged to radially expand when exposed to a fluid. 7. The system of claim 1, wherein the mandrel comprises the guidewire attached to the mandrel first end, and wherein the guidewire is constructed and arranged to be removed from the mandrel first end. 8. The system of claim 1, wherein the system further comprises: a fluid delivery device operably attachable to at least one of the mandrel first end or the mandrel second end. 9. The system of claim 1, wherein the system further comprises: a rotational drive constructed and arranged to rotate the mandrel. 10. The system of claim 1, wherein the fiber matrix delivery assembly comprises an electrospinning unit. 11. The system of claim 1, wherein the tubular member comprises: living tissue selected from the group consisting of: vein, saphenous vein, artery, lymphatic duct, vas deferens, tear duct, intestine, esophagus, ureter, urethra, trachea, bronchi, duct tissue, Eustachian tube, fallopian tube, and combinations thereof. 12. The system of claim 1, wherein the tubular member comprises a saphenous vein. 13. The system of claim 1, wherein the tubular member comprises: an artificial conduit selected from the group consisting of: polytetrafluoroethylene (PTFE), expanded PTFE (ePTFE), polyvinylidene fluoride/hexafluoropropylene (PVDF-HFP), polyester, silicone, polyethylene, polypropylene, polyester-based polymer, polyether- based polymer, thermoplastic rubber, and combinations thereof. 14. The system of claim 1, wherein the porous portion of the mandrel comprises side holes. 15. The system of claim 14, wherein the side holes are equidistantly spaced.
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