System for analysis of complex rhythm disorders
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61B-005/04
A61B-005/024
A61B-005/02
A61B-005/0402
A61B-005/046
A61B-005/0464
A61B-005/00
A61B-018/14
A61B-005/0452
A61B-018/12
A61B-005/0245
A61B-005/044
A61B-005/042
A61B-007/04
A61B-008/08
A61B-018/00
출원번호
US-0177317
(2016-06-08)
등록번호
US-9955879
(2018-05-01)
발명자
/ 주소
Narayan, Sanjiv
Rappel, Wouter-Jan
출원인 / 주소
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
대리인 / 주소
Musick, Eleanor
인용정보
피인용 횟수 :
0인용 특허 :
155
초록▼
A system to generate a representation of a rhythm disorder includes a plurality of sensors disposed at multiple locations spatially in relation to the heart, wherein cardiac information signals are sensed. A processor receives and analyzes the activation onsets of the cardiac information signals to
A system to generate a representation of a rhythm disorder includes a plurality of sensors disposed at multiple locations spatially in relation to the heart, wherein cardiac information signals are sensed. A processor receives and analyzes the activation onsets of the cardiac information signals to determine an arrangement of activation onsets. A representation that indicates the clinical source of the rhythm disorder is generated based on the arrangement of the activation onsets.
대표청구항▼
1. A system for generating a representation of a clinical source of a complex heart rhythm disorder comprising: a plurality of sensors disposed at multiple locations in relation to the heart to sense cardiac information signals; anda processor interfacing with the plurality of sensors, wherein the p
1. A system for generating a representation of a clinical source of a complex heart rhythm disorder comprising: a plurality of sensors disposed at multiple locations in relation to the heart to sense cardiac information signals; anda processor interfacing with the plurality of sensors, wherein the processor is configured to: receive data associated with the cardiac information signals, the data comprising an activation onset of each cardiac information signal at each location such that a plurality of activation onsets at a plurality of locations is collected;determine a sequential arrangement of activation onsets derived from the data associated with the cardiac information signals; andgenerate a sensory representation based on the sequential arrangement of activation onsets, wherein the sensory representation indicates a region of the heart associated with the clinical source of the complex heart rhythm disorder. 2. The system of claim 1, wherein the sequential arrangement is based on an ordering of the activation onsets. 3. The system of claim 2, wherein the sensory representation comprises an activation trail based on the sequential arrangement of activation onsets as ordered. 4. The system of claim 3, wherein the activation trail comprises activations that revolve around or radially emanate from a core region, the core region indicative of the complex heart rhythm disorder. 5. The system of claim 3, wherein the sensory representation comprises an activation trail that is repeating. 6. The system of claim 3, wherein the activation trail comprises a rotational pattern or an outwardly emanating pattern. 7. The system of claim 6, wherein the rotational pattern or the outwardly emanating pattern is repeating. 8. The system of claim 3, wherein the processor is further configured to visually depict on a display device the sensory representation comprising the activation trail. 9. The system of claim 8, wherein the display device is arranged for visually depicting the activation onsets in relation to a location of each sensor to display the activation trail. 10. The system of claim 3, wherein the processor is further configured to perform: analyzing the cardiac information signals at one or more of the multiple locations; andapproximating the activation trail based on the analyzing. 11. The system of claim 10, wherein analyzing comprises analyzing one or more of rate, regularity, amplitude, duration, and location. 12. The system of claim 3, wherein the processor is further configured to determine an approximate core region in relationship to the activation trail. 13. The system of claim 12, wherein the activation trail revolves about the approximate core region or the activation trail emanates outwardly from the approximate core region. 14. The system of claim 12, wherein the approximate core region is a rotor or a focal activation. 15. The system of claim 1, wherein the sensory representation indicates the clinical source of the complex heart rhythm disorder by providing a visualization of at least one of existence, type, and location of the complex heart rhythm disorder. 16. The system of claim 1, wherein the sensory representation indicates the clinical source of the complex heart rhythm disorder by providing at least one of an image, textual, tactile, graphic and auditory visualization of a rotor or other cause of the complex heart rhythm disorder. 17. The system of claim 1, wherein the sensory representation is one or more of a visual display and auditory signal. 18. The system of claim 17, wherein the visual display includes one or more of a real-time presentation, textual data, and graphical data. 19. The system of claim 17, wherein the auditory signal comprises an auditory identification of the clinical source of the complex heart rhythm disorder. 20. The system of claim 1, wherein the sensory representation comprises an activation trail based on a sequential ordering of the activation onsets. 21. The system of claim 1, wherein the processor is further configured to generate the sensory representation based on an activation trail, the activation trail based on at least one of a direct phase, Hilbert transform, wavelet transform, phase-delay, and time-domain analysis associated with the cardiac information signals. 22. The system of claim 1, wherein the sensory representation is at least one of a set of data, an image, a graphic, and a textual description. 23. The system of claim 1, wherein the sensory representation comprises a rotational pattern or an outwardly emanating pattern. 24. The system of claim 23, wherein the rotational pattern or the outwardly emanating pattern is repeating. 25. The system of claim 1, wherein one or more of the multiple locations are within the heart or proximal to the heart. 26. The system of claim 1, further comprising a sensor device to sense the cardiac information signals at the multiple locations using the plurality of sensors. 27. The system of claim 26, wherein the sensor device performs sensing of the cardiac information signals at the multiple locations concurrently. 28. The system of claim 26, wherein the sensor device performs sensing of the cardiac information signals at the multiple locations stepwise. 29. The system of claim 1, further comprising an ablation component for modifying or destroying regions of the heart responsible for a cause of the complex heart rhythm disorder. 30. The system of claim 1, further comprising a plurality of sensors including an ablation component for modifying or destroying regions of the heart responsible for a cause of the complex heart rhythm disorder. 31. The system of claim 1, further comprising software for processing said data. 32. The system of claim 1, further comprising determining whether a cause of the complex heart rhythm disorder is a primary cause of the complex heart rhythm disorder. 33. The system of claim 32, wherein criteria used for determining whether the cause of the complex heart rhythm disorder is a primary cause are selected from the group consisting of the number of activation trail repetitions, the rate of activation trail repetitions, the number of localized causes, the volume of tissue contained within the activation trail, whether the cause is localized or dispersed, the location of the cause within the heart, and combinations thereof. 34. The system of claim 32, wherein the complex heart rhythm disorders are selected from a group consisting of supraventricular tachycardia, supraventricular bradycardia, ventricular bradycardia, atrial fibrillation, atrial flutter, atrial tachycardia, ventricular tachycardia, ventricular fibrillation or a combination thereof. 35. The system of claim 1, further comprising an electronic control system for connecting to one or more of a plurality of sensors. 36. The system of claim 35, further comprising an electronic connection switching component for independently switching connections between said plurality of sensors and said electronic control system. 37. The system of claim 1, wherein the activation onsets are arranged based on their relative activation onset time. 38. The system of claim 1, wherein the processor is further configured to determine at least one approximate core region that is a rotor. 39. The system of claim 38, wherein said at least one approximate core region is a focal activation. 40. The system of claim 1, wherein the processor is further configured to filter signal noise. 41. The system of claim 1, wherein an activation time associated with an activation onset of a cardiac information signal at a location includes the activation onset time and its corresponding offset time. 42. The system of claim 41, wherein the activation onset time includes a diastolic interval. 43. The system of claim 1, wherein the system comprises a storage device for storing data associated with said activation trail in a database. 44. The system of claim 1, wherein the processor is further configured to augment or modify the activation trail based upon comparisons with similar activation trail patterns associated with data stored in a database. 45. The system of claim 1, wherein the processor is further configured to: construct an electrograph having a voltage-time tracing of heart function at each of the multiple locations; andinsert a physiological pattern in the electrograph at the activation onset of each cardiac information signal at each location. 46. The system of claim 45, wherein the physiological pattern comprises a pattern selected from the group consisting of a prior recording from a same patient, a prior recording from a different patient, and a simulated pattern. 47. The system of claim 45, wherein the physiological pattern is a pattern selected from a group consisting of a unipolar electrogram, a bipolar electrogram, an action potential representation, and a combination thereof. 48. The system of claim 45, wherein the physiological pattern is adjusted for rate. 49. The system of claim 45, wherein the physiological pattern is a model of cellular ion function or a model of a pharmacological ligand.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (155)
Desai Jawahar M. (4141 Cowell Blvd. ; No. 38 Davis CA 95616), Apparatus and method for cardiac ablation.
White Harley (Redmond WA) Bocek Joseph M. (Seattle WA), Automatic gain control and method for enabling detection of low and high amplitude depolarization activation waves of th.
Robert W. Stadler ; Shannon Nelson, Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same.
Stadler Robert W. ; Nelson Shannon, Axis shift analysis of electrocardiogram signal parameters especially applicable for multivector analysis by implantable medical devices, and use of same.
Branham Barry H. (Ballwin MO) Cox James L. (Ladue MO) Boineau John P. (Ladue MO) Schuessler Richard B. (Ballwin MO), Computerized three-dimensional cardiac mapping with interactive visual displays.
Shen Xiguang (North Point CNX) Feng Genquan (Beijing CNX) Lian Ruan (Beijing CNX) Wang Changqing (Beijing CNX) Lian Jing (Shenzhen CNX) Liu Chi (Guangzhou CNX) Lai Shizhong (Guangzhou CNX) Yang Jilin, Correlative analysis in multi-domain processing of cardiac signals.
Sweeney,Robert J.; Lovett,Eric G., Curvature based method for selecting features from an electrophysiologic signal for purpose of complex identification and classification.
Ackmann James J. (Wauwatosa WI) Christman Norbert T. (Wauwatosa WI) Ebert Thomas J. (Glendale WI), Impedance cardiograph and method of operation utilizing peak aligned ensemble averaging.
Dupree, Daniel A.; Nguyen, Tuan; Panescu, Dorin; Whayne, James G.; McGee, David; Swanson, David K., Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions.
Dupree, Daniel A.; Nguyen, Tuan; Panescu, Dorin; Whayne, James G.; McGee, David; Swanson, David K., Interactive systems and methods for controlling the use of diagnostic or therapeutic instruments in interior body regions.
Hauck,John A.; Schweitzer,Jeff A.; Craven,Michael; Afonso,Valtino; Cotner,Holly; Callaghan,Frank; Schultz,John, Method and apparatus for catheter navigation and location and mapping in the heart.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Greenhut, Saul E.; Kleckner, Karen J.; Krause, Paul G.; Mahajan, Veerdhaval, Method and apparatus for detecting arrhythmias in a medical device.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Kleckner, Karen J.; Krause, Paul G., Method and apparatus for detecting arrhythmias in a medical device.
Ghanem, Raja N.; Stadler, Robert W.; Zhang, Xusheng; Kleckner, Karen J.; Krause, Paul G., Method and apparatus for detecting arrhythmias in a medical device.
Stadler Robert ; Nelson Shannon ; Stylos Lee ; Sheldon Todd J., Method and apparatus for filtering electrocardiogram (ECG) signals to remove bad cycle information and for use of physiologic signals determined from said filtered ECG signals.
Gunderson, Bruce D.; Patel, Amisha S.; Bounds, Chad A.; Brown, Mark L., Method and apparatus for identifying oversensing using far-field intracardiac electrograms and marker channels.
Gunderson, Bruce D.; Patel, Amisha S.; Bounds, Chad A.; Brown, Mark L., Method and apparatus for identifying oversensing using far-field intracardiac electrograms and marker channels.
Bj?rling, Anders; Hedberg, Sven-Erik; Lindegren, Ulf; Lindgren, Anders, Method and circuit for detecting cardiac rhythm abnormalities by analyzing time differences between unipolar signals from a lead with a multi-electrode tip.
Efimov, Igor R.; Krinski, Valentin I.; Nikolski, Vladimir P., Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries.
Efimov, Igor R.; Krinski, Valentin I.; Nikolski, Vladimir P., Method for low-voltage termination of cardiac arrhythmias by effectively unpinning anatomical reentries.
Goldreyer Bruce N. (30311 Palos Verdes Dr. East Rancho Palos Verdes CA 90274), Method for spatially specific electrophysiological sensing for mapping, pacing and ablating human myocardium and a cathe.
Svenson Robert H. (Charlotte NC) King Wendell (North Oaks MN), Process of identification of a ventricular tachycardia (VT) active site and an ablation catheter system.
Tarjan,Peter P.; Lu,Chih Cheng; Besio,Walter, Single or multi-mode cardiac activity data collection, processing and display obtained in a non-invasive manner.
Ciaccio, Edward J.; Wit, Andrew L.; Tosti, Alexis Christine, System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation.
Ciaccio,Edward J.; Wit,Andrew L.; Tosti,Alexis Christine, System and method for determining reentrant ventricular tachycardia isthmus location and shape for catheter ablation.
Rudy,Yoram; Ramanathan,Charulatha; Ghanem,Raja; Jia,Ping, System and methods for noninvasive electrocardiographic imaging (ECGI) using generalized minimum residual (GMRes).
Swanson David K. ; Whayne James G. ; Panescu Dorin, Systems and methods for acquiring making time-sequential measurements of biopotentials sensed in myocardial tissue.
Panescu Dorin ; Swanson David K. ; Mirotznik Mark S. ; Schwartzman David S. ; Foster Kenneth R., Systems and methods for examining the electrical characteristic of cardiac tissue.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.