[특허]Keratoprosthesis, and system and method of corneal repair using same

Keratoprosthesis, and system and method of corneal repair using same 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	A61F-002/14
출원번호	US-0426195 (2013-09-04)
등록번호	US-9974646 (2018-05-22)
국제출원번호	PCT/US2013/057949 (2013-09-04)
국제공개번호	WO2014/039495 (2014-03-13)
발명자 / 주소	Parel, Jean-Marie Sawatari, Yoh Perez, Victor L. Bernal, Andres
출원인 / 주소	UNIVERSITY OF MIAMI
대리인 / 주소	Marshall, Gerstein & Borun LLP
인용정보	피인용 횟수 : 0 인용 특허 : 145

초록 ▼

A keratoprosthesis and system and method of using same for corneal repair. The keratoprosthesis comprises a biocompatible support and an optic member disposed through a channel within the support. The support includes metal, preferably titanium, and treated, such as by sandblasting and/or acid etching, to create textured surfaces that promote soft tissue adhesion. A locking member interconnects the optic member and support. An outer surface of the locking member a collar extending from the support and disposed around the optic member is also metal, preferably titanium, and is similarly treated to promote soft tissue adhesion. A locking member interconnects the optic member and support. The system includes the keratoprosthesis positioned within an isolated soft tissue segment of a non-ocular tissue, such as buccal mucosa, placed on the anterior cornea. The method includes removing corneal epithelium, isolating and transplanting a segment of soft tissue to the de-epithelialized cornea, creating a receiving area in the soft tissue, positioning a keratoprosthesis relative to the receiving area anterior to the cornea, and securing the keratoprosthesis.

대표청구항 ▼

1. A keratoprosthesis comprising: an optic member disposable in vision facilitating relation to an eye of a patient;a biocompatible support having a channel disposed through said support, the channel defining a collar extending away from an anterior side of said biocompatible support;said optic member disposed in said channel of said support such that the collar is disposed in at least partially surrounding relation to the optic member, said biocompatible support structured to be secured in place at a position anterior to a cornea of a patient's eye and to engage soft tissue;at least a portion of a surface of said biocompatible support including a treated surface structured to promote adhesion of soft tissue thereto, wherein said biocompatible support comprises a metallic material; and wherein said collar and said biocompatible support comprise the same metallic material. 2. The keratoprosthesis as recited in claim 1, wherein said biocompatible support comprises titanium. 3. The keratoprosthesis as recited in claim 2 wherein said biocompatible support is made entirely of titanium. 4. The keratoprosthesis as recited in claim 2 wherein said biocompatible support comprises a core of at least one type of biocompatible material and at least one outer surface comprising titanium. 5. The keratoprosthesis as recited in claim 1 wherein said biocompatible support is disposable and securable in spaced relation to an anterior cornea. 6. The keratoprosthesis as recited in claim 1 wherein said biocompatible support is structured to engage a receiving area in soft tissue located anterior to the cornea. 7. The keratoprosthesis as recited in claim 1 wherein said biocompatible support comprises a diameter of approximately 10 millimeters. 8. The keratoprosthesis as recited in claim 1 wherein said biocompatible support comprises an elliptical shape. 9. The keratoprosthesis as recited in claim 1 wherein said biocompatible support comprises a plurality of apertures disposed along a periphery thereof to facilitate attachment of said biocompatible support. 10. The keratoprosthesis as recited in claim 9 wherein each of said plurality of apertures comprises a diameter of approximately 0.3 millimeters. 11. The keratoprosthesis as recited in claim 1 wherein said biocompatible support comprises a plurality of openings disposed throughout said biocompatible support in nutrient transmitting relation to the cornea. 12. The keratoprosthesis as recited in claim 11 wherein at least one of said plurality of openings comprise a contour to increase the surface area of said biocompatible support. 13. The keratoprosthesis as recited in claim 12 wherein at least one of said plurality of openings comprises a concave contour. 14. The keratoprosthesis as recited in claim 13 wherein at least one of said plurality of openings comprises a conical configuration. 15. The keratoprosthesis as recited in claim 1 wherein substantially all of an outer surface of said biocompatible support comprises a treated surface structured to promote adhesion of soft tissue thereto. 16. The keratoprosthesis as recited in claim 1 wherein said treated surface of said biocompatible support comprises a texture having microstructures ranging from generally about 0.5 to 2 microns in diameter. 17. The keratoprosthesis as recited in claim 1 wherein said surface is treated with at least one of sandblasting and acid etching to create enhanced soft tissue adhesion capabilities. 18. The keratoprosthesis as recited in claim 1 further comprising the collar disposed fully surrounding an outer wall of said optic member. 19. The keratoprosthesis as recited in claim 1 wherein said collar comprises at least one treated surface structured to promote adhesion of soft tissue thereto. 20. The keratoprosthesis as recited in claim 19 wherein said at least one treated surface of said collar comprises a texture having microstructures ranging from generally about 0.5 to 2 microns in diameter. 21. The keratoprosthesis as recited in claim 20 wherein said collar is treated with at least one of sandblasting and acid etching to create said texture of said at least one treated surface. 22. The keratoprosthesis as recited in claim 1 wherein said collar comprises a height of approximately 3 millimeters. 23. The keratoprosthesis as recited in claim 1 wherein said optic member comprises polymethylmethacrylate (PMMA). 24. The keratoprosthesis as recited in claim 1 wherein said optic member is secured within said channel of said biocompatible support. 25. The keratoprosthesis as recited in claim 1 further comprising a locking member structured and disposed in interconnecting securing relation between said optic member and said support. 26. The keratoprosthesis as recited in claim 25 wherein said locking member is disposed in at least partially encircling relation to said optic member. 27. The keratoprosthesis as recited in claim 26 wherein said locking member is disposed between said optic member and the collar extending from an anterior side of said biocompatible support. 28. The keratoprosthesis as recited in claim 25 wherein said locking member is secured to said optic member with methylethylketone (MEK). 29. The keratoprosthesis as recited in claim 25 wherein said locking member comprises polymethylmethacrylate (PMMA).

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Gibson David (Irvine CA) Lerner Michael (Shawnee OK) Nordquist Robert (Oklahoma City OK) Reich Cary (Irvine CA), Treated corneal prosthetic device.
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Lambiase, Alessandro, Use of nerve growth factor for the storage, culture or treatment of cornea.
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Schneider Richard T. (17 Alachua Highlands Alachua FL 32615) Keates Richard H. (71 Whitman Court Irvine CA 92715), Vision simulating apparatus and method.
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IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

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Keratoprosthesis, and system and method of corneal repair using same 원문보기

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Keratoprosthesis, and system and method of corneal repair using same 원문보기

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전체(0) 논문(0) 특허(0) 보고서(0)

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