A method and device for delivering a pharmaceutical to the airway of a human or animal patient, in one aspect, includes a dose drum formed into a cylinder and including a plurality of dose compartments for containing individual doses. In another aspect, the device may include a reservoir containing
A method and device for delivering a pharmaceutical to the airway of a human or animal patient, in one aspect, includes a dose drum formed into a cylinder and including a plurality of dose compartments for containing individual doses. In another aspect, the device may include a reservoir containing a pharmaceutical material in bulk form and a metering recess for metering the pharmaceutical material to form a pharmaceutical dose. Another aspect provides an inhaler with a combined reservoir and dosing chamber configured to contain multiple doses of a pharmaceutical material.
대표청구항▼
1. An inhaler for delivering a pharmaceutical to the airway of a human or animal patient, comprising: a dose drum in the form of an elongate cylinder, the dose drum including a plurality of dose compartments located on an outer cylindrical surface of the dose drum for containing individual doses of
1. An inhaler for delivering a pharmaceutical to the airway of a human or animal patient, comprising: a dose drum in the form of an elongate cylinder, the dose drum including a plurality of dose compartments located on an outer cylindrical surface of the dose drum for containing individual doses of a pharmaceutical;a flexible sheath formed of a tape, foil or film surrounding and covering in part the outer cylindrical surface of the dose drum, wherein the sheath is movably slidable on the dose drum to uncover one or more of said dose compartments to the outer cylindrical surface of the dose drum;a dose chamber; anda flow channel, through which the individual dose is delivered to the airway of the patient;wherein the dose chamber includes an opening for receiving said doses of a pharmaceutical, and wherein the dose chamber is a resonance chamber coupled to a vibration device. 2. The inhaler of claim 1, wherein the vibration device is a piezo-electric device. 3. The inhaler of claim 1, wherein the vibration device is connected to a frequency generator for controlling the vibration of the vibration device. 4. The inhaler of claim 1, further comprising a drive for advancing and positioning the dose drum. 5. The inhaler of claim 1, wherein the sheath is removed from a single dose compartment when delivering the individual dose contained in said dose compartment to the dose chamber. 6. A method of delivering a pharmaceutical material to the airway of a patient, human or animal, the method comprising the steps of: providing the pharmaceutical material in a reservoir connected to a metering device;metering the pharmaceutical material with the metering device to form a pharmaceutical dose;moving the pharmaceutical dose into a dose chamber;deaggregating the pharmaceutical material of the pharmaceutical dose; anddelivering the pharmaceutical dose from the dose chamber to the airway of the patient via a flow channel, wherein the metering device comprises a metering drum in one form of an elongate cylinder which rotates upon its axis, at least one metering recess located on an outer cylindrical surface of the metering drum; and a flexible sheath formed of a tape, foil or film surrounding and covering in part the outer cylindrical surface of the metering drum, wherein the sheath is movably slidable relative to the metering drum to uncover one or more of said metering recesses to the outer cylindrical surface of the dose drum;wherein the dose chamber includes an opening for receiving said pharmaceutical material, and wherein said dose chamber is a resonance chamber coupled to a vibration device, and wherein the step of deaggregating the pharmaceutical material involves activating the vibration device to create a synthetic jet thereby delivering the pharmaceutical dose from the dose chamber to the airway of a patient via the flow channel. 7. The method of claim 6, wherein the step of moving the pharmaceutical dose into the dose chamber involves rotating the metering drum. 8. The method of claim 6, wherein the pharmaceutical material is in the form of a dry powder. 9. An inhaler for delivering a pharmaceutical material to the airway of a patient, human or animal, comprising: a reservoir containing a pharmaceutical material;at least one metering recess metering the pharmaceutical material to form a pharmaceutical dose;a dose chamber;a flow channel, connected to the dose chamber, through which the pharmaceutical dose is delivered from the dose chamber to the airway of the patient;a metering drum configured as an elongate cylinder which rotates upon its axis, the at least one metering recess being located on an outer cylindrical surface of the metering drum; anda flexible sheath formed of a tape, foil or film surrounding and covering in part the outer cylindrical surface of the metering drum, wherein the sheath is movably slidable relative to the metering drum to uncover one of said metering recesses to the outer cylindrical surface of the dose drum;wherein the dose chamber includes an opening for receiving said pharmaceutical dose, and wherein the dose chamber is a resonance chamber coupled to a vibration device. 10. The inhaler of claim 9, further comprising a drive for rotating the metering drum. 11. The inhaler of claim 9, wherein the pharmaceutical is in the form of a dry powder. 12. The inhaler of claim 9, wherein the vibration device is connected to a frequency generator for controlling the vibration of the vibration device.
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