초록 ▼

An adjuvant composition of the present invention contains lauryl alcohol and propylene glycol. Contents of the lauryl alcohol and the propylene glycol are 0.5 to 25% by mass and 8.0 to 99.5% by mass, relative to the total mass of the adjuvant composition, respectively. The lauryl alcohol is dissolve

An adjuvant composition of the present invention contains lauryl alcohol and propylene glycol. Contents of the lauryl alcohol and the propylene glycol are 0.5 to 25% by mass and 8.0 to 99.5% by mass, relative to the total mass of the adjuvant composition, respectively. The lauryl alcohol is dissolved, and the adjuvant composition is used for transdermal or transmucosal administration.

대표청구항 ▼

1. An adjuvant composition for transdermal or transmucosal administration, comprising lauryl alcohol, propylene glycol, and glycerol, wherein contents of the lauryl alcohol, the propylene glycol, and the glycerol are 0.5 to 20% by mass, 49 to 90% by mass, and 8.0 to 50% by mass, relative to the tota

1. An adjuvant composition for transdermal or transmucosal administration, comprising lauryl alcohol, propylene glycol, and glycerol, wherein contents of the lauryl alcohol, the propylene glycol, and the glycerol are 0.5 to 20% by mass, 49 to 90% by mass, and 8.0 to 50% by mass, relative to the total mass of the adjuvant composition, respectively,wherein the lauryl alcohol is dissolved in the propylene glycol and glycerol, andwherein a ratio of the content of the propylene glycol to the content of the glycerol is from 1.0 to 9.0. 2. The adjuvant composition according to claim 1, wherein a ratio of the content of the propylene glycol to the content of the lauryl alcohol is from 1.0 to 99. 3. An adjuvant preparation, comprising the adjuvant composition according to claim 1. 4. The adjuvant preparation according to claim 3, wherein a content of the adjuvant composition is 50 to 100% by mass relative to the total mass of the adjuvant preparation. 5. The adjuvant preparation according to claim 3, which is an ointment, a cream, a gel, a suppository, a hydrogel patch preparation, a patch preparation, a lotion, a solution, an impregnated-type preparation, or a blister. 6. The adjuvant preparation according to claim 5, wherein the patch preparation is a matrix-type tape preparation, a laminated-type tape preparation, or a reservoir-type patch preparation. 7. The adjuvant preparation according to claim 3, which is administrated to a skin or a mucous membrane by microneedle puncture, needle-free injection, skin abrading, or mucous membrane abrading. 8. The adjuvant preparation according to claim 3, wherein at least a part of the microneedle is coated with the adjuvant preparation, and which is administrated to a skin or a mucous membrane by puncture. 9. The adjuvant preparation according to claim 3, which is administrated by iontophoresis, sonophoresis, or electroporation. 10. The adjuvant preparation according to claim 3, which is administrated to an intact skin, an intact mucous membrane, a skin that had been subjected to physical or chemical treatment, or a mucous membrane that had been subjected to physical or chemical treatment. 11. The adjuvant preparation according to claim 10, wherein the physical or chemical treatment is at least one treatment selected from the group consisting of a heat-treatment, an ultrasonic treatment, an electric field treatment, a magnetic field treatment, a pressure treatment, an alkali treatment, a laser irradiation, an abrading treatment, and a microneedle treatment. 12. The adjuvant preparation according to claim 3, which is administrated to the skin or mucous membrane either before the administration of an antigen or after the administration of an antigen. 13. A kit comprising the adjuvant composition according to claim 1. 14. The kit according to claim 13, further comprising an apparatus for an antigen or an antigen administration.