An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the
An autoinjector apparatus is disclosed which comprises a single-use cassette and an autoinjector. The cassette comprises a housing and a sleeve movably disposed in the housing. A syringe may be disposed in the sleeve and secured therein with a lock cap. The lock cap is affixed to a distal end of the sleeve and contacts the distal end of the syringe. A shield remover extends through an opening in a proximal end of the housing for removing a needle shield which covers a needle of the syringe. A cassette identification arrangement is provided on a surface of the housing to enable the autoinjector to identify the cassette. The autoinjector is provided with a detector for reading the cassette identification arrangement.
대표청구항▼
1. A single-use cassette for use with an autoinjector, the cassette comprising: a housing;an inner sleeve disposed in the housing and movable between first and second positions,a syringe disposed in the inner sleeve;a lock cap for securing the syringe in the inner sleeve, the lock cap including an e
1. A single-use cassette for use with an autoinjector, the cassette comprising: a housing;an inner sleeve disposed in the housing and movable between first and second positions,a syringe disposed in the inner sleeve;a lock cap for securing the syringe in the inner sleeve, the lock cap including an elastomeric bumper, the lock cap affixed to a distal end of the inner sleeve with the elastomeric bumper contacting a distal end of the syringe, wherein the distal end of the inner sleeve comprises at least one receptacle and the lock cap comprises at least one arm member for inserting into the receptacle; anda shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, wherein the shield remover comprises an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette. 2. The cassette of claim 1, wherein the at least one arm member of the lock cap comprises a barb arrangement for gripping an inner surface of the at least one receptacle of the inner sleeve. 3. The cassette of claim 1, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing. 4. The cassette of claim 1, wherein the syringe includes a barrel and an injection needle. 5. The cassette of claim 1, further comprising a therapeutic product in the syringe. 6. The cassette of claim 5, wherein the therapeutic product is selected from the group consisting of Epogen®, Aranesp®, Enbrel®, Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva® and Prolia®. 7. The cassette of claim 5, wherein the therapeutic product is an antibody to IL-17 Receptor A, an antagonist of angiopoietin-2, a TNF blocker or inhibitor. 8. The cassette of claim 7, wherein the therapeutic product is a TNF blocker or inhibitor and is etanercept, adalimumab, certolizumab, golimumab or infliximab. 9. The cassette of claim 1, further comprising a cassette identification arrangement on a surface of the housing to enable the autoinjector to identify the cassette. 10. The cassette of claim 9, wherein the cassette identification arrangement comprises at least one projection. 11. An apparatus for injection of a therapeutic product, the apparatus comprising: an autoinjector; anda single-use cassette for use with the injector, the cassette comprising: a housing;an inner sleeve disposed in the housing and movable between first and second positions;a syringe disposed in the inner sleeve;a lock cap for securing the syringe in the inner sleeve, the lock cap including an elastomeric bumper, the lock cap affixed to a distal end of the inner sleeve with the elastomeric bumper contacting a distal end of the syringe, wherein the distal end of the inner sleeve comprises at least two receptacles and the lock cap comprises at least arm members, each inserted into one of the receptacles; anda shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette, and wherein the shield remover comprises an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette. 12. The apparatus of claim 11, wherein each arm member of the lock cap comprises a barb arrangement for gripping an inner surface of the corresponding receptacle of the inner sleeve. 13. The apparatus of claim 11, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette. 14. The apparatus of claim 13, wherein the autoinjector comprises a pin for pushing the tab out of the aperture defined in the wall of the housing when the cassette is placed in the injector to thereby allow the shield remover to be removed from the cassette. 15. The apparatus of claim 11, further comprising a therapeutic product in the syringe. 16. The apparatus of claim 15, wherein the therapeutic product is selected from the group consisting of Epogen®, Aranesp®, Enbrel®, Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva®, and Prolia®. 17. The apparatus of claim 15, wherein the therapeutic product is an antibody to IL-17 Receptor A, an antagonist to angiopoietin-2, or a TNF blocker or inhibitor. 18. The apparatus of claim 15, wherein the therapeutic product is a TNF blocker or inhibitor and is etanercept, adalimumab, certolizumab, golimumab or infliximab. 19. The apparatus of claim 11, further comprising a cassette identification arrangement on a surface of the housing to enable the autoinjector to identify the cassette. 20. The apparatus of claim 19, wherein the cassette identification arrangement comprises at least one projection or a detector for reading the cassette identification arrangement to identify the cassette. 21. An apparatus for injection of a therapeutic product, the apparatus comprising: an autoinjector; and a single-use cassette for use with the injector, the cassette comprising: a housing;a sleeve disposed in the housing and movable between first and second positions;a syringe disposed in the sleeve; anda shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, the shield remover comprising a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette;wherein the autoinjector comprises a pin for pushing the tab out of the aperture defined in the wall of the housing when the cassette is placed in the injector to thereby allow the shield remover to be removed from the cassette. 22. The apparatus of claim 21, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette. 23. The apparatus of claim 21, wherein the shield remover comprises an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette. 24. The apparatus of claim 21, further comprising a therapeutic product in the syringe, wherein the therapeutic product is Epogen®, Aranesp®, Enbrel®, Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva®, Prolia®, an antibody to IL-17 Receptor A, an antagonist to angiopoietin-2, a TNF blocker or inhibitor, etanercept, adalimumab, certolizumab, golimumab, or infliximab. 25. A single-use cassette for use with an autoinjector, the cassette comprising: a housing;a sleeve disposed in the housing and movable between first and second positions, wherein the sleeve is capable of having a syringe disposed therein; anda shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, the shield remover comprising an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette. 26. The cassette of claim 25, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette. 27. The cassette of claim 25, further comprising a syringe disposed in the sleeve, wherein the syringe includes a barrel and an injection needle. 28. The cassette of claim 27, further comprising a therapeutic product in the syringe, wherein the therapeutic product is Epogen®, Aranesp®, Enbrel®, Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva® and Prolia®, an antibody to IL-17 Receptor A, an antagonist of angiopoietin-2, a TNF blocker or inhibitor, etanercept, adalimumab, certolizumab, golimumab, or infliximab. 29. The cassette of claim 28, wherein the therapeutic product is etanercept. 30. An apparatus for injection of a therapeutic product, the apparatus comprising: an autoinjector; and a single-use cassette for use with the injector, the cassette comprising: a housing;a sleeve disposed in the housing and movable between first and second positions;a syringe disposed in the sleeve; anda shield remover extending through an opening in a proximal end of the housing for removing a needle shield from the syringe, the shield remover comprising an elongated body having a proximal end and a distal end, the distal end comprising at least one flexible tongue that expands outwardly when the shield remover is removed from the cassette to prevent the shield remover from being reinserted into the cassette. 31. The apparatus of claim 30, wherein the shield remover comprises a spring-biased tab, the tab disposed within an aperture defined in a wall of the housing to prevent removal of the shield remover from the cassette. 32. The apparatus of claim 30, wherein the autoinjector comprises a pin for pushing the tab out of the aperture defined in the wall of the housing when the cassette is placed in the injector to thereby allow the shield remover to be removed from the cassette. 33. The apparatus of claim 30, further comprising a therapeutic product in the syringe, wherein the therapeutic product is Epogen®, Aranesp®, Enbrel®, Neulasta®, Neupogen®, Nplate®, Vectibix®, Sensipar®, Xgeva®, Prolia®, an antibody to IL-17 Receptor A, an antagonist to angiopoietin-2, a TNF blocker or inhibitor, etanercept, adalimumab, certolizumab, golimumab, or infliximab. 34. The apparatus of claim 33, wherein the therapeutic product is etanercept.
연구과제 타임라인
LOADING...
LOADING...
LOADING...
LOADING...
LOADING...
이 특허에 인용된 특허 (212)
Bedzyk, Laura A.; Fahnestock, Stephen R.; Gruber, Tanja Maria; Okeefe, Daniel P.; Rouviere, Pierre E., Acid-cleavable linkers exhibiting altered rates of acid hydrolysis.
Wilmot John G. ; Goldberg Jeffrey L. ; Page Jon ; Ketcham Cliff ; Castleberry Jeffrey P. ; Morton Jason ; Edsall Dave ; Boyd Robert R. ; Hill Robert L., Automatic injector.
Raven, Sophie Rebecca; Young, Matthew Egerton; Greenhalgh, Paul; Kirkwood, Stephen Pilip; Mathews, Colin James; Daintrey, Joseph William; Wilmot, John G., Container for medicament automatic injector and automatic injector adapted therefor.
Sarnoff Stanley J. (Bethesda MD) Lopez Claudio (Gaithersburg MD) Dalling N. Lawrence (Cross Junction VA), Conveniently carried frequent use auto-injector with improved cap structure.
Haber Terry M. (Lake Forest CA) Smedley William H. (Lake Elsinore CA) Foster Clark B. (Laguna Niguel CA), Device for containing and opening a glass ampule and for transferring liquid within the ampule to a container.
Edwards, Eric Shawn; Edwards, Evan Thomas; Licata, Mark J.; Meyers, Paul F.; Weinzierl, David A., Devices, systems and methods for medicament delivery.
Denance Raymond (Le Commodore H41 ; Marina Baie des Anges 06270 Villeneuve Loubet FRX), Electromechanical injection apparatus for medical and veterinary use actuated by a trigger.
Smith Mark Timothy (375 St. James Street London ; Ontario CAX N6A 1X7 ) Ellis James William (London CAX) Keogh Gerald Peter (London CAX), Electronic syringe.
Gabriel Jochen (Stuttgart DEX) Bechtold Herbert (Ehningen DEX) Hambrecht Gerhard (Rosenberg-Sindolzheim DEX) Nothdurft Klaus (Stuttgart DEX), Injection device for injection, especially self-administered injection, of medicament, including mechanisms for nulling.
Denance Raymond (Le commodore H41 ; Marina Baie des Anges 06270 Villeneuve Loubet FRX), Injection device having a stabilizing sight which actuates a safety valve for the needle.
Mesa C. Michael (Boyds MD) Dalling N. Lawrence (Cross Junction VA) Lowery Sandra A. (St. Charles MO) Monroe O. Napoleon (Bethesda MD), Injection device having polyparaxylylene coated container.
Degironimo Bruno (Billerica MA) Silverman Neil D. (Framingham MA) Oliver William R. (Chelmsford MA) Rideout Eugene C. (Billerica MA), Injection system.
Lilley Stephen J. (Sawston GBX) Taylor Hugh F. (Sawston GBX) Theobald David R. (Huntingdon GBX) Carlson Craig J. (Andover MA) Rosen David I. (Arlington MA) Johnson Thomas R. (Milford NH), Medical injection system and method, gas spring thereof and launching device using gas spring.
Lilley Stephen John,GBX ; Taylor Hugh Francis,GBX ; Theobald David Reginald,GBX ; Carlson Craig J. ; Rosen David I. ; Johnson Thomas R., Medical injection system and method, gas spring thereof and launching device using gas spring.
Edwards, Eric S.; Edwards, Evan T.; Licata, Mark J.; Meyers, Paul F.; Weinzierl, David A.; Williamson, IV, T. Spencer, Medical injector with compliance tracking and monitoring.
Edwards, Eric S.; Edwards, Evan T.; Licata, Mark J.; Meyers, Paul F.; Weinzierl, David A.; Williamson, IV, T. Spencer, Medical injector with compliance tracking and monitoring.
Simonsen, Jan Henning; Poulsen, Jens Ulrik; Rokkjaer, Kent Halfdan; Christensen, Lars Hofmann; Aasmul, S.o slashed.ren; Iav, Steffen, Medical system and a method of controlling the system for use by a patient for medical self treatment.
Castellano Thomas P. (Beverly Hills CA) Schumacher Robert (Beverly Hills CA), Medication delivery device with a microprocessor and characteristic monitor.
Bendek Antonio A. ; Burbank ; III John E. ; Bush ; Jr. Charles L. ; Gabel Jonathan B. ; Giambattista Lucio ; Hoeck Roger W. ; Taylor Malcolm E., Medication delivery pen having an improved clutch assembly.
Atkins Judy M. (Hillsborough NC) Comfort Benjamin J. (Hillsborough NC) Liebelt Ralph A. (Durham NC), Method and device for detection of tissue infiltration.
Rowe Stephen C. (Wellesley MA) Hubbell Jeffrey A. (San Marino CA) Herman Stephen J. (Andover MA) Sun Vae (Palo Alto CA) Lang Michael F. (Roswell GA) Selecman George E. (Marblehead MA) Ahari Frederick, Method for local application of polymeric material to tissue.
Dalamagas Photios P. (74 Amston Rd. Colchester CT 06415) Sapia Mark A. (5 Ann La. Canton CT 06022), Method to sense the tissue for injection from a hypodermic needle.
Pawelka Gerhard E. F. (Lexington MA) Stringer Christopher J. (San Francisco CA) Marsh Matthew (San Francisco CA) Karshmer David L. (San Francisco CA) Lada Christopher O. (Palo Alto CA) Schoenberg Ste, Multi-cartridge medication injection device.
Paxton Gerald R. (1407 S. Arcadia St. Boise ID 83705) Seid Norman W. (3865 Barstow Ct. Boise ID 83709) Gilman Garry L. (9750 Klondike Ct. Boise ID 83709), Multifunctional retractable needle type general purpose disabling syringe having enhanced safety features and related me.
Neer Charles (Milford OH) Fago Frank M. (Mason OH) Dieterlen Paul E. (Covington KY) Goethel James H. (Cincinnati OH), Power injector for injecting fluid into animals.
Hehl Karl,DEX ; Wybitul Oliver Kay,DEX ; Gierth Michael Manfred,DEX ; Huth Joachim,DEX, Process for regulating the tool inner pressure curve of a cyclically working machine.
Kramer George C. (5 Tiki Cir. Galveston TX 77554) Thomas William B. (Fremont CA) Wilson Jay (Portola Valley CA), System and method for rapid vascular drug delivery.
Kramer George C. (Galveston TX) Spoon Herbert H. (San Antonio TX) Miller Larry J. (Spring Branch TX) Collette David J. (San Antonio TX) Zamorano Rubn G. (San Antonio TX) Jenkinson Joel P. (Galveston , System and method for rapid vascular drug delivery.
Flaherty,J. Christopher; Makower,Joshua; Evard,Philip C.; MacAulay,Patrick E.; Whitt,Jason B.; Colloton,Robert C.; Macfarlane,K. Angela, Systems and methods for delivering drugs to selected locations within the body.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.