A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end, and a filter element extending from the body frame portion. Each of the one or more tethers is attach
A thrombus treatment device includes a support wire, a body frame portion that is disposed about an axis defined by the support wire, one or more tethers that each have a first end and a second end, and a filter element extending from the body frame portion. Each of the one or more tethers is attached at its first end to the body frame portion, and at its second end to a collar that couples the second end of each of the multiple tethers to the support wire. When the collar is positioned substantially within a region interior of the body frame portion, a rotational actuation of the support wire causes a swiveling motion of the one or more tethers.
대표청구항▼
1. A method of treating a thrombus, comprising: introducing a catheter to a patient and advancing a distal end of the catheter to a treatment site;advancing a thrombus treatment device through a lumen of the catheter, the thrombus treatment device comprising: (a) a support tube, (b) a body frame por
1. A method of treating a thrombus, comprising: introducing a catheter to a patient and advancing a distal end of the catheter to a treatment site;advancing a thrombus treatment device through a lumen of the catheter, the thrombus treatment device comprising: (a) a support tube, (b) a body frame portion that is disposed about an axis defined by the support tube, the body frame portion including a proximal end and a distal end, (c) a filter portion that extends from the distal end of the body frame portion, and (d) multiple tethers each having a first end and a second end, wherein the first end of each of the multiple tethers extends out a proximal end of the support tube, the tethers extending through a lumen of the support tube and out a distal end of the support tube and engaging the body frame portion near the distal end of the body frame portion and extending to the proximal end of the body frame portion, the second end of each of the multiple tethers being coupled to the body frame portion near the proximal end of the body frame portion;positioning the thrombus treatment device within the lumen of the catheter such that the body frame portion is generally aligned with at least a portion of a thrombus at the treatment site; andproximally withdrawing the catheter, wherein the body frame portion expands from a collapsed state to an expanded state with a radial force sufficient to embed in the thrombus in response to the proximal withdrawal of the catheter. 2. The method of claim 1, wherein each tether extends from the distal end of the support tube to the proximal end of the body frame portion such that an intermediate portion of each tether engages the body frame portion near the distal end of the body frame portion. 3. The method of claim 1, wherein each tether of the multiple tethers forms a loop around the body frame portion near the proximal end of the body frame portion. 4. The method of claim 1, wherein the multiple tethers collectively form a loop around the body frame portion near the proximal end of the body frame portion. 5. The method of claim 1, wherein the body frame portion is adapted to open a flow channel through the thrombus when the body frame portion expands and contacts the thrombus. 6. The method of claim 1, wherein the filter portion is adapted to capture thrombus particles displaced by the expansion of the body frame portion. 7. The method of claim 1, further comprising pretreating the filter portion with a thrombogenic material or autologous blood. 8. The method of claim 7, wherein the thrombus treatment device acts as an occluder while the thrombogenic material or autologous blood restricts blood flow through the filter portion. 9. The method of claim 8, further comprising delivering a thrombolytic agent to the thrombus. 10. The method of claim 1, further comprising, applying proximally directed force to the at least one tether such that a portion of the at least one tether moves proximally relative to the support tube, the proximally directed force causing the proximal end and the distal end of the body frame to collapse radially from the expanded state to the collapsed state, and proximally withdrawing the thrombus treatment device from the treatment site with the thrombus treatment device in its collapsed state. 11. A method of treating a thrombus, comprising: introducing a catheter to a patient and advancing a distal end of the catheter to a treatment site;advancing a thrombus treatment device in a collapsed state through a lumen of the catheter, the thrombus treatment device comprising: (a) a support tube, (b) a body frame portion disposed about an axis defined by the support tube, (c) a filter portion, and (d) at least one tether, said at least one tether having a first end and a second end, the first end extending out a proximal end of the support tube and the second end extending out of a distal end of the support tube such that the second end is coupled to the body frame portion near a proximal end of the body frame portion;positioning the thrombus treatment device within the lumen of the catheter such that the body frame portion is generally aligned with at least a portion of a thrombus at the treatment site; andproximally withdrawing the catheter such that the body frame portion radially expands from a collapsed state to an expanded state, said radial expansion causing a portion of the at least one tether to move relative to the support tube, said radial expansion causing a portion of the body frame to embed in the thrombus. 12. The method of claim 11, wherein the at least one tether extends from the distal end of the support tube to the proximal end of the body frame portion such that an intermediate portion of each tether engages the body frame portion near the distal end of the body frame portion. 13. The method of claim 11, wherein each tether of the multiple tethers forms a loop around the body frame portion near the proximal end of the body frame portion. 14. The method of claim 11, wherein the thrombus treatment device comprises multiple tethers, and wherein the multiple tethers collectively form a loop around the body frame portion near the proximal end of the body frame portion. 15. The method of claim 11, wherein the body frame portion is adapted to open a flow channel through the thrombus when the body frame portion expands and contacts the thrombus. 16. The method of claim 11, wherein the filter portion is adapted to capture thrombus particles displaced by the expansion of the body frame portion. 17. The method of claim 11, further comprising pretreating the filter portion with a thrombogenic material or autologous blood. 18. The method of claim 17, wherein the thrombus treatment device acts as an occluder while the thrombogenic material or autologous blood restricts blood flow through the filter portion. 19. The method of claim 18, further comprising delivering a thrombolytic agent to the thrombus. 20. The method of claim 11, further comprising, applying proximally directed force to the at least one tether such that a portion of the at least one tether moves proximally relative to the support tube, the proximally directed force causing the proximal end and the distal end of the body frame to collapse radially from the expanded state to the collapsed state, and proximally withdrawing the thrombus treatment device from the treatment site with the thrombus treatment device in its collapsed state.
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