초록

A double conjugate molecule made of a retinoid, an organic acid, particularly an a-hydroxy acid, and an alcohol or acyl group, is provided which is useful in treating skin conditions, particularly aging. The retinoid, organic acid, and alcohol/acyl group are preferably linked via ester bonds.

대표청구항 ▼

1. A method of treating a skin condition in a human, comprising: contacting the skin of the human in need of such treatment with an effective amount of a composition comprising the molecule of formula (Id), wherein R3 is H or alkyl consisting of 1 carbon atom, andR6 is alkyl consisting of 1, 2, 3,

1. A method of treating a skin condition in a human, comprising: contacting the skin of the human in need of such treatment with an effective amount of a composition comprising the molecule of formula (Id), wherein R3 is H or alkyl consisting of 1 carbon atom, andR6 is alkyl consisting of 1, 2, 3, or 4 carbon atoms; andwherein the skin condition is acne, photodamage, fine lines and wrinkles, or a combination thereof. 2. The method of claim 1, wherein the composition further comprises: a carrier; and0.01 to 0.5 wt %, relative to the total weight of the composition, of the molecule of formula Id. 3. The method of claim 1, wherein the composition further comprises: an α-hydroxy acid. 4. The method of claim 1, wherein the molecule has the formula (If) 5. The method of claim 1, wherein the molecule has the formula (Ig) 6. The method of claim 1, wherein the molecule of formula (Id) is present in an amount of 0.01 to 0.25 wt %. 7. The method of claim 1, wherein the molecule of formula (Id) is present in an amount of 0.01 to less than 0.2 wt %. 8. The method of claim 1, wherein the molecule of formula (Id) is present in the amount of 0.02 to 0.175 wt %.