Dispensing device, storage device and method for dispensing a formulation
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-011/00
A61M-015/00
출원번호
US-0808686
(2008-12-24)
등록번호
US-10124129
(2018-11-13)
우선권정보
EP-08000010 (2008-01-02)
국제출원번호
PCT/EP2008/011112
(2008-12-24)
§371/§102 date
20100730
(20100730)
국제공개번호
WO2009/083244
(2009-07-09)
발명자
/ 주소
Dunne, Stephen T.
Moser, Achim
출원인 / 주소
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
대리인 / 주소
Dernier, Esq., Matthew B.
인용정보
피인용 횟수 :
0인용 특허 :
287
초록▼
The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle
The invention relates to a dispensing device, a storage device and a method for dispensing a medical formulation. Multiple doses of the formulation are stored in a carrier having multiple storage members, each storage member containing a single dose. Each storage member comprises one duct or nozzle for dispensing the respective dose. The dispensing direction of the ducts or nozzles is directed in a lengthwise or indexing direction of the carrier. The storage device of the carrier is a peelable blister strip, wherein the ducts or nozzles can be opened one after the other by peeling the blister strip.
대표청구항▼
1. A dry powder inhaler (1) for dispensing a medical powder formulation (2) containing a drug, as a powder spray (3), wherein the medical powder formulation (2) contains a drug, and wherein the dry powder inhaler (1) comprises: a storage device (4) including a carrier (5) having multiple storage mem
1. A dry powder inhaler (1) for dispensing a medical powder formulation (2) containing a drug, as a powder spray (3), wherein the medical powder formulation (2) contains a drug, and wherein the dry powder inhaler (1) comprises: a storage device (4) including a carrier (5) having multiple storage members (6) in a flexible, band-like arrangement, wherein each of said multiple storage members (6) includes: (i) a respective storage cavity (9) containing a dose of the medical powder formulation (2), and (ii) a respective nozzle (11) having an outlet oriented such that the medical powder dose is dispensed from the respective storage cavity (9), through the respective nozzle, and outward from the outlet in a dispensing direction (12),characterized in that the respective nozzle (11) includes a duct (10) that forms a channel from the storage cavity (9) to the outlet, where the duct (10) is formed integrally with the storage cavity (9), and the dispensing direction (12) of the respective nozzle (11) is directed at least in a lengthwise or indexing direction of the carrier (5). 2. The dry powder inhaler according to claim 1, characterized in that the carrier (5) is a blister strip. 3. The dry powder inhaler according to claim 1, characterized in that the carrier (5) comprises a base layer (7) and a peelable cover layer (8), wherein the multiple storage members (6) are inserted or held between these layers (7, 8) before and/or during dispensing. 4. The dry powder inhaler according to claim 1, characterized in that the multiple storage members (6) are parts made separately from the carrier (5). 5. The dry powder inhaler according to claim 1, characterized in that the multiple storage members (6) are formed by the carrier (5), a base layer (7) and a cover layer (8) of the carrier (5). 6. The dry powder inhaler according to claim 1, characterized in that each of the multiple storage members (6) is a molded element, a cartridge, a capsule or a container. 7. The dry powder inhaler according to claim 1, characterized in that each of the multiple storage members (6) is rigid or flexible. 8. The dry powder inhaler according to claim 1, characterized in that the dry powder inhaler (1) further comprises an opening, connecting and/or supply means (14), a piercing element (15) for opening or piercing the multiple storage members (6) individually and/or supplying pressurized gas to each of the multiple storage members (6) to dispense the dose from each of said multiple storage members (6). 9. The dry powder inhaler according to claim 1, characterized in that the dry powder inhaler (1) further comprises a means for providing pressurized gas for dispensing the medical powder formulation (2), wherein the dry powder inhaler (1) comprises a manually operated air pump (13) as means for providing pressurized gas. 10. The dry powder inhaler according to claim 1, characterized in that the dry powder inhaler (1) is designed such that the carrier (5) is capable of being moved or indexed stepwise from one of said multiple storage members (6) to the next one of said multiple storage members (6). 11. The dry powder inhaler according to claim 1, characterized in that the multiple storage members (6) or nozzles (11) are sealed by one common sealing or cover layer (8). 12. The dry powder inhaler of claim 1, wherein the storage device (4) or carrier (5) is a peelable blister strip, wherein the nozzle (11) is capable of being opened one after the other by peeling the blister strip. 13. The dry powder inhaler of claim 1, wherein the carrier (5) carries the storage members (6) formed separately from the carrier (5) rigidly or in a unmovable manner and is adapted that each of the storage members (6) or the nozzle (11) is capable of being opened without movement of the storage members (6) or a base layer (7) thereof by opening or peeling a common sealing or cover layer (8). 14. The dry powder inhaler of claim 1, further comprising a mouthpiece including a longitudinal body having an inlet end and an outlet end, the inlet end being in fluid communication with the outlet of the respective nozzle (11), and the outlet end for delivering the dose of the medical powder formulation (2) to a user, wherein the outlet of the nozzle (11), the inlet end of the longitudinal body, and the outlet end of the longitudinal body are oriented along the dispensing direction (12). 15. The dry powder inhaler of claim 1, wherein the duct (10) is always open and remains open even prior to dispensing of the powder formulation. 16. A storage device (4) for a medical powder formulation (2) containing a drug, for a dry powder inhaler (1), the storage device (4) comprising: a carrier (5) having multiple storage members (6) in a flexible, band-like arrangement, wherein each of said multiple storage members (6) includes: (i) a respective storage cavity (9) containing a dose of the medical powder formulation (2), and (ii) a respective nozzle (11) having an outlet oriented such that the respective medical powder formulation dose (2) is dispensed from the respective storage cavity (9), through the respective nozzle, and outward from the outlet in a dispensing direction (12),characterized in that the respective nozzle (11) includes a duct (10) that forms a channel from the storage cavity (9) to the outlet, where the duct (10) is formed integrally with the storage cavity (9), and the dispensing direction (12) of the respective nozzle (11) is directed in a lengthwise direction of the carrier (5). 17. A method, comprising: dispensing a medical powder formulation (2) containing a drug, as a dry powder spray (3) from a blister strip comprising multiple storage members (6), wherein each of said multiple storage members (6) includes (i) a respective storage cavity (9) containing a dose of the medical powder formulation (2), and (ii) a respective nozzle (11) having an outlet oriented such that the medical powder formulation dose (2) is dispensed from the respective storage cavity (9), through the respective nozzle, and outward from the outlet in a dispensing direction (12), wherein the respective nozzle (11) includes a duct (10) that forms a channel from the storage cavity (9) to the outlet, where the duct (10) is formed integrally with the storage cavity (9), and the dispensing direction (12) of the respective nozzle (11) is directed in a lengthwise direction of the carrier (5), andpeeling the blister strip to open each of the multiple storage members (6) and expose the respective nozzle (11), one after the other, so that the medical powder formulation dose (2) in each of said multiple storage members (6) is dispensed one after the other. 18. Method according to claim 17, characterized in that each of the storage members (6) or nozzle (11) is sealed by one common sealing or cover layer (8), wherein the common sealing or cover layer (8) is peeled. 19. Method according to claim 17, characterized in that the storage members (6) are individually connected to a supply of pressurized gas by piercing each of the respective storage members (6) by means of a piercing element (15).
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