[특허]Cell culture apparatus for co-culture of cells

[미국특허] Cell culture apparatus for co-culture of cells 원문보기

IPC분류정보
국가/구분	United States(US) Patent 등록
국제특허분류(IPC7판)	C12M-001/00 C12M-003/00 C12M-001/04 C12M-001/42
출원번호	US-0063040 (2016-03-07)
등록번호	US-10144910 (2018-12-04)
발명자 / 주소	Tanner, Allison Jean Martin, Gregory Roger
출원인 / 주소	Corning Incorporated
대리인 / 주소	Wilks, Susan S.
인용정보	피인용 횟수 : 0 인용 특허 : 74

초록 ▼

A multilayered cell culture apparatus for the co-culturing of at least two cell types is disclosed. The cell co-culture apparatus is defined as an integral structure having a plurality of cell culture chambers in combination with tracheal space(s). The body of the apparatus has imparted therein gas permeable membranes in combination with tracheal spaces that will allow the free flow of gases between some cell culture chambers and the external environment. In addition, some cell culture chambers may have limited access to air creating relatively lower oxygen content cell culture chambers. The size of the apparatus, and location of an optional neck section, allows for its manipulation by standard automated assay equipment, further making the apparatus amenable to high throughput applications.

대표청구항 ▼

1. A multi-layer cell culture vessel for the co-culture of cells comprising: a first manifold providing access to a first plurality of cell culture chambers through ports in each of the first plurality of cell culture chambers, but does not provide access to a second plurality of cell culture chambers,a second manifold providing access to the second plurality of cell culture chambers through ports in each of the second plurality of cell culture chambers, but does not provide access to the first plurality of cell culture chambers;wherein the first plurality of cell culture chambers are adjacent to and alternate with the second plurality of cell culture chambers to form a multi-layer cell culture vessel, and wherein each of the first cell culture chambers are separated from each of the adjacent second cell culture chambers by a gas permeable liquid permeable membrane; and,at least one tracheal chamber adjacent to two cell culture chambers and separated from at least one of the adjacent cell culture chambers by a gas permeable, liquid impermeable membrane. 2. The vessel of claim 1 wherein the gas permeable, liquid impermeable membrane comprises microporous membrane. 3. The vessel of claim 1 wherein the microporous membrane comprises track-etched membrane. 4. The vessel of claim 1 wherein the tracheal chamber permits gaseous exchange between said gas permeable, liquid impermeable surface of said cell culture chamber and external atmosphere. 5. The vessel of claim 1 wherein at least one of the first manifold or the second manifold comprises a valve. 6. The vessel of claim 1 wherein at least one of the first manifold and the second manifold comprise tubing. 7. The vessel of claim 1 wherein the at least one of the first manifold and the second manifold comprises a necked opening. 8. The vessel of claim 7 further comprising a cap. 9. The vessel of claim 1 further comprising a third manifold which provides access to a third plurality of cell culture chambers through ports in each of the third plurality of cell culture chambers, but does not provide access to the first plurality of cell culture chambers or the second plurality of cell culture chambers, and wherein the third plurality of cell culture chambers are adjacent to the cell culture chambers from the first or second plurality of cell culture chambers by a gas permeable liquid permeable membrane. 10. A multi-layer cell co-culture culture vessel comprising: a first plurality of cell culture chambers in a multi-layer cell culture vessel, each cell culture chamber comprising a first port;a second plurality of cell culture chambers in a multi-layer cell culture vessel, each cell culture chamber comprising a second port;at least one tracheal chamber adjacent to each cell culture chamber and separated from the adjacent cell culture chamber by a gas permeable, liquid impermeable membrane;a manifold comprising two openings and a divider which separates a first manifold opening from a second manifold opening,wherein the first manifold opening provides access to the first plurality of cell culture chambers through the first ports, but does not provide access to the second plurality of cell culture chambers, andwherein the second manifold opening provides access to the second group of cell culture chambers through the second ports, but does not provide access to the first plurality of cell culture chambers. 11. The vessel of claim 10 wherein the first plurality of cell culture chambers are adjacent to and alternate with the second plurality of cell culture chambers to form a multi-layer cell culture vessel, and wherein the first cell culture chambers are separated from the adjacent second cell culture chambers by a gas permeable liquid permeable membrane. 12. The vessel of claim 10 wherein the gas permeable, liquid impermeable membrane comprises microporous membrane. 13. The vessel of claim 10 wherein the microporous membrane comprises track-etched membrane. 14. The vessel of claim 10 wherein the tracheal chamber permits gaseous exchange between said gas permeable, liquid impermeable surface of said cell culture chamber and external atmosphere. 15. The vessel of claim 10 wherein the openings of the manifold each comprise a valve. 16. The vessel of claim 10 wherein the openings of the manifold each comprise tubing. 17. The vessel of claim 10 wherein the manifold comprises necked openings. 18. The vessel of claim 17 further comprising a cap.

이 특허에 인용된 특허 (74) 인용/피인용 타임라인 분석

Robbins, Jr., Neil F., Advanced roller bottle system for cell and tissue culturing.
상세보기
Feye,Glen, Apparatus and method for co-culturing of cells.
상세보기
Wilhelm Minuth (Neue Welt 1 8401 Hohengebraching DEX), Apparatus for cultivating cells.
상세보기
Hirose Toshiki (Kawasaki JPX) Shimazaki Koji (Saga JPX) Nakamura Takashi (Kawasaki JPX) Shiraishi Atsuo (Kawasaki JPX) Kawashima Hiroki (Kawasaki JPX) Nakayama Tatsuya (Kawasaki JPX), Apparatus for defoaming and controlling aerobic culture fermentation.
상세보기
Bartal Arie H. (Habikurim Street 40 Haifa ILX), Apparatus for enhancing cell growth, preservation and transport.
상세보기
Freeman, Alex R., Array-based microenvironment for cell culturing, cell monitoring and drug-target validation.
상세보기
Barbera-Guillem, Emilio, Automated cell management system for growth and manipulation of cultured cells.
상세보기
Kersten Jean,BEX ; Bader Augustinus,DEX, Bioreactor.
상세보기
Wechsler, Thomas; Baer, Ulrich; Oehr, Christian; Graeve, Thomas, Bioreactor.
상세보기
Sarem, Farzin; Sarem Damerdji, Leila-Ouassila, Cell and tissue culture device with controlled culture fluid flow.
상세보기
Johansson Arne (Lejre DKX) Esser Peter (Copenhagen DKX), Cell cultivating device.
상세보기
Lacey,William J.; Ryan,John A.; Vaughan,Laurence M.; Wall,Joseph C.; Youngbear,Kathy M., Cell cultivating flask.
상세보기
Wall, Joseph C.; Lyman, George F., Cell cultivating flask and method for using the cell cultivating flask.
상세보기
Verma Dharmvir S. (5831 Rutherglen Houston TX 77096), Cell culture and continuous dialysis flask and method.
상세보기
Amiot Bruce P. (Delano MN), Cell culture apparatus.
상세보기
Amiot Bruce P. (Roseville MN), Cell culture apparatus.
상세보기
Codner Meryl (St. Paul MN), Cell culture apparatus and method.
상세보기
Emilio Barbera-Guillem, Cell culture apparatus and method for culturing cells.
상세보기
Barbera-Guillem, Emilio; Nelson, M. Bud, Cell culture apparatus and methods of use.
상세보기
Emilio Barbera-Guillem ; M. Bud Nelson, Cell culture apparatus and methods of use.
상세보기
Cremonese Joseph G. (227 Maple Dr. Greensburg PA 15601), Cell culture flask utilizing a membrane barrier.
상세보기
Toner, Mehmet; Tilles, Arno W.; Balis, Ulysses J.; Yarmush, Martin L.; Cosman, Maury D.; Dimilla, Paul A., Cell culture systems and methods for organ assist devices.
상세보기
Kiel Johnathan L. ; Alls John L., Cell culture vessel with self-maintained atmosphere.
상세보기
Gruenberg Michael, Cell growing device for in vitro cell population expansion.
상세보기
Gruenberg Micheal (Minneapolis MN), Cell growing device for in vitro cell population expansion.
상세보기
DiMilla, Paul A.; Cosman, Maury D.; Halych, Rachel; Romito, Lisa; Gemmeti, Chris; Odlum, Kevin, Chamber with adjustable volume for cell culture and organ assist.
상세보기
Nuzzo Michael J. (Newark NJ), Closure assembly for cell culture vessels.
상세보기
Vogler Erwin A. (Wilmington DE), Compartmentalized cell-culture device and method.
상세보기
Wilson John R. ; Wolf Martin L., Compartmentalized tissue culture bag.
상세보기
Wilson John R. (173 Windsor La. New Brighton MN 55112) Wolf Martin L. (1280 Keston St. St. Paul MN 55108), Compartmentalized tissue culture flask.
상세보기
Spaulding Glenn F. (Houston TX), Constructing a high density cell culture system.
상세보기
Berry Eric S. (32 Valleyview Dr. Merrimack NH 03054) Ramberg Mark J. (24 Brattle St. Worcester MA 01606), Continuous high-density cell culture system.
상세보기
Hoshi Kouichi (Susono JPX) Goudo Masaru (Susono JPX) Suzuki Mitsuhiro (Susono JPX) Masaki Ritsuo (Susono JPX) Hashizume Akira (Susono JPX) Ohnaka Hidemi (Susono JPX), Control device for heater for oxygen sensor operative to correct target resistance with reference to standard power supp.
상세보기
Atsushi Okada JP; Yoshitaka Teratani JP; Naohiro Kadota JP; Hisao Itoh JP, Culture device for aerobic culture and method of controlling foams by defoaming.
상세보기
Stevens Timothy A., Culture vessel.
상세보기
Falkenberg Frank W. (Witten DEX) Nagels Hans-Otto (Bovenden DEX) Kohn Heinz-Gerhard (Dransfeld DEX), Culture vessel for cell cultures.
상세보기
Geiss, Kevin T., Culturing cells in a chamber in a stack of chambers.
상세보기
Mohr, Ulrich; Aufderheide, Michaela, Culturing device and method for culturing cells or tissue components.
상세보기
Bader Augustinus (Hinter den Langen Hoefen 16 D-31275 Lehrte DEX), Device for the treatment of cell cultures.
상세보기
Barbera-Guillem, Emilio, Device having microchambers and microfluidics.
상세보기
Howell Gary W. (Elkton MD) Irr Joseph D. (Newark DE) Nahapetian Ara T. (Wilmington DE), Dot matrix membrane cell expansion.
상세보기
Schwarz Ray P. (Friendswood TX), Gas permeable bioreactor and method of use.
상세보기
Schwarz Ray P. (Friendswood TX) Archibald ; III Frederick A. (Clear Lake Shores TX), Gas permeable bioreactor and method of use.
상세보기
Schwarz Ray P. ; Anderson Charles D., Gas permeable bioreactor and method of use.
상세보기
Cline Martin J. (441 Alma Real Dr. Pacific Palisades CA 90272), Gas permeable culture flask and method for culturing mammalian cells.
상세보기
Wolf David A. (Houston TX) Sams Clarence F. (Houston TX) Schwarz Ray P. (Friendswood TX), High aspect reactor vessel and method of use.
상세보기
Spaulding Glenn F. (Houston TX), High density cell culture system.
상세보기
Schwarz Ray P. (League City TX) Wolf David A. (Houston TX) Trinh Tinh T. (Houston TX), Horizontally rotated cell culture system with a coaxial tubular oxygenator.
상세보기
Lyman George F. (Rocky Point ME), Laboratory flask.
상세보기
Pykett,Mark J.; Rosenzweig,Michael; Scadden,David T.; Poznansky,Mark C., Lymphoid tissue-specific cell production from hematopoietic progenitor cells in three-dimensional devices.
상세보기
Abasolo, Nora; Lucas, Rick D.; Krause, Betsey, Mailer for cell culture device.
상세보기
Hubbard Peter J. (Darien CT), Membrane cell culturing device.
상세보기
Nagels Hans-Otto,DEX ; Schroder Dieter,DEX ; Kopowski Eckart,DEX, Method and apparatus for co-culturing cells.
상세보기
Soodak Charles I. (Silver Spring MD) Ulrich Robert R. (Eldersburg MD), Method and apparatus for making fluorocarbon film plastic bags using a laser.
상세보기
Bader, Augustinus, Method and device for growing and/or treating cells.
상세보기
Brown Peter C. ; Wininger Mark T. ; Oakley Robert V., Method for culturing animal cells.
상세보기
Singh Vijay, Method for culturing cells using wave-induced agitation.
상세보기
Schultze,Joachim L.; Freeman,Gordon J.; Gribben,John G.; Nadler,Lee M., Methods of inducing a T cell mediated immune response by administering antigen presenting B cells.
상세보기
Barbera-Guillem, Emilio; Lucas, Rick D., Microincubator comprising a cell culture apparatus and a transparent heater.
상세보기
Kapur, Ravi; Adams, Terri, Miniaturized cell array methods and apparatus for cell-based screening.
상세보기
Kapur,Ravi; Giuliano,Kenneth, Miniaturized cell array methods and apparatus for cell-based screening.
상세보기
Miyamori Takao (Otake JPX) Uchida Makoto (Otake JPX) Enomoto Kanehiko (Tokyo JPX) Sakimae Akihiro (Otake JPX) Numazawa Ryozo (Otake JPX), Multi-layered porous hollow fiber membrane for use in cell culture.
상세보기
Smith Sidney T. ; Bacehowski David V. ; Kolanko William ; Rosenbaum Larry ; Smith Stephen L. ; Bender James G. ; Woo Lecon ; Ling Michael T. K., Multilayer gas-permeable container for the culture of adherent and non-adherent cells.
상세보기
Klebe Robert J. (Helotes TX) Grant Anne M. (San Antonio TX), Perfusable culture device.
상세보기
Young Roy E. (Six Mile SC) Adelberg Jeffrey W. (Clemson SC), Plant propagation system.
상세보기
Augustine Bader DE, Process and device for culturing and/or treating cells.
상세보기
Puchinger Herwig (Neu Isenburg DEX) Mueller Ulrich (Ruesselsheim DEX) Sernetz Manfred (Krofdorf DEX), Process for the in-vitro biosynthesis of hormones, especially insulin.
상세보기
Mussi Edward F. (Hewitt NJ) Gray Harry E. (Woodbridge NJ), Roller bottle for trans-membrane co-culture of cells and method for its use.
상세보기
Coughlin Paul Thomas ; Lyman George Frederick ; Mathus Gregory, Self contained cell growth system.
상세보기
Turner Marc Leighton,GBX ; Murphy William Gerrard,GBX, Stem cell immobilization.
상세보기
Minchinton Andrew I. (Vancouver CAX), System for growing multi-layered cell cultures.
상세보기
Ashby, Matthew; Shoemaker, Daniel D., Targeted methods of drug screening using co-culture methods.
상세보기
Stevens Timothy A. ; Mussi Edward, Tissue culture flask.
상세보기
Cai Xuejun ; Lin Yalin ; Lin Guohe,CNXITX 524241, Universal tissue culture flask.
상세보기

활용도 분석정보

상세보기

다운로드

내보내기

활용도 Top5 특허

해당 특허가 속한 카테고리에서 활용도가 높은 상위 5개 콘텐츠를 보여줍니다.
더보기 버튼을 클릭하시면 더 많은 관련자료를 살펴볼 수 있습니다.

IPC	Description
A	생활필수품
A62	인명구조; 소방(사다리 E06C)
A62B	인명구조용의 기구, 장치 또는 방법(특히 의료용에 사용되는 밸브 A61M 39/00; 특히 물에서 쓰이는 인명구조 장치 또는 방법 B63C 9/00; 잠수장비 B63C 11/00; 특히 항공기에 쓰는 것, 예. 낙하산, 투출좌석 B64D; 특히 광산에서 쓰이는 구조장치 E21F 11/00)
A62B-1/08	.. 윈치 또는 풀리에 제동기구가 있는 것

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표IPC 관리번호, 국가코드, 자료구분, 상태, 출원번호, 출원일자, 공개번호, 공개일자, 공고번호, 공고일자, 등록번호, 등록일자, 발명명칭(한글), 발명명칭(영문), 출원인(한글), 출원인(영문), 출원인코드, 대표출원인, 출원인국적, 출원인주소, 발명자, 발명자E, 발명자코드, 발명자주소, 발명자 우편번호, 발명자국적, 대표IPC, IPC코드, 요약, 미국특허분류, 대리인주소, 대리인코드, 대리인(한글), 대리인(영문), 국제공개일자, 국제공개번호, 국제출원일자, 국제출원번호, 우선권, 우선권주장일, 우선권국가, 우선권출원번호, 원출원일자, 원출원번호, 지정국, Citing Patents, Cited Patents
저장형식	Text(ASCII format) Excel format PIAS분석(.xls)
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증

[미국특허] Cell culture apparatus for co-culture of cells 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

이 특허에 인용된 특허 (74) 인용/피인용 타임라인 분석

활용도 분석정보

활용도 Top5 특허

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

연합인증

[미국특허] Cell culture apparatus for co-culture of cells 원문보기

초록 ▼

대표청구항 ▼

연구과제 타임라인

전체(0) 논문(0) 특허(0) 보고서(0)

전체(0) 논문(0) 특허(0) 보고서(0)

이 특허에 인용된 특허 (74) 인용/피인용 타임라인 분석

활용도 분석정보

활용도 Top5 특허 더보기

관련 콘텐츠

특허 원문 보기

IPC 상위 출원인

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

선택된 텍스트

활용도 Top5 특허