Reduced-pressure treatment and debridement systems and methods
원문보기
IPC분류정보
국가/구분
United States(US) Patent
등록
국제특허분류(IPC7판)
A61M-035/00
A61M-001/00
A61F-013/00
A61M-001/36
A61M-027/00
출원번호
US-0588747
(2012-08-17)
등록번호
US-10172984
(2019-01-08)
발명자
/ 주소
Locke, Christopher Brian
Robinson, Timothy Mark
McNulty, Amy K.
출원인 / 주소
KCI Licensing, Inc.
인용정보
피인용 횟수 :
0인용 특허 :
105
초록▼
A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic d
A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic debridement at the treatment area. The reduced-pressure treatment system includes a manifold that is adapted to cover the hydrogel and distribute reduced pressure to the tissue site. The reduced-pressure treatment system also includes a sealing drape for forming a fluid seal over the tissue site and manifold. Other systems, methods, and dressings are presented.
대표청구항▼
1. A reduced-pressure treatment system for debriding a treatment area of a tissue site, the system comprising: a hydrogel adapted to cover the treatment area, wherein the hydrogel comprises a blocked acid debriding agent comprising an alpha hydroxy acid bound to a blocking material;a manifold adapte
1. A reduced-pressure treatment system for debriding a treatment area of a tissue site, the system comprising: a hydrogel adapted to cover the treatment area, wherein the hydrogel comprises a blocked acid debriding agent comprising an alpha hydroxy acid bound to a blocking material;a manifold adapted to cover the hydrogel and distribute reduced pressure to the tissue site; anda sealing drape for placing over the tissue site and manifold, the sealing drape adapted to form a fluid seal over the tissue site and manifold;a reduced-pressure interface for delivering reduced pressure to the manifold; anda reduced-pressure subsystem for providing reduced pressure. 2. The reduced-pressure treatment system of claim 1, wherein the blocked acid debriding agent comprises lactic acid and an arginine group. 3. The reduced-pressure treatment system of claim 1, wherein the blocked acid debriding agent comprises glycolic acid and arginine. 4. The reduced-pressure treatment system of claim 1, wherein the hydrogel is adapted to soften and break apart over time in response to exposure to wound fluid. 5. The reduced-pressure treatment system of claim 4, wherein the manifold is adapted to absorb the hydrogel after the hydrogel softens. 6. The reduced-pressure treatment system of claim 1, wherein the manifold is adapted to absorb debrided necrotic tissue. 7. The reduced-pressure treatment system of claim 1, wherein the hydrogel is a viscous gel. 8. The reduced-pressure treatment system of claim 1, further comprising an intermediate foam layer between the hydrogel and the manifold. 9. A method of manufacturing a reduced-pressure wound dressing for treating a tissue site and debriding a treatment area, the method comprising: providing a hydrogel,wherein the hydrogel is adapted to cover the treatment area, andwherein the hydrogel comprises a blocked acid debriding agent comprising an alpha hydroxy acid bound to a blocking material;providing a manifold, wherein the manifold is adapted to cover the hydrogel and distribute reduced pressure to the tissue site;providing a sealing drape for placing over the tissue site and manifold, the sealing drape adapted to form a fluid seal over the tissue site and manifold;providing a reduced-pressure interface for delivering a reduced pressure to the manifold; andproviding a reduced-pressure subsystem. 10. The method of claim 9, further comprising providing an intermediate foam layer for disposing between the hydrogel and the manifold. 11. The method of claim 9, wherein the hydrogel is adapted to soften and break apart over time in response to exposure to wound fluid. 12. The method of claim 9, wherein the manifold is adapted to absorb the hydrogel after the hydrogel softens. 13. A method for treating a tissue site on a patient, the method comprising: defining a treatment area by applying a hydrogel to a portion of the tissue site, wherein the treatment area comprises tissue to be debrided and the hydrogel comprises a blocked acid debriding agent comprising an alpha hydroxy acid bound to a blocking material;applying a manifold over the hydrogel, wherein the manifold is adapted to deliver reduced-pressure to the tissue site;applying a sealing drape over the tissue site and manifold to form a fluid seal over the tissue site and manifold; andproviding reduced pressure to the manifold. 14. The method of claim 13, wherein the tissue to be debrided comprises a tissue selected from a group consisting of necrotic tissue, damaged tissue, infected tissue, contaminated tissue, and adherent tissue. 15. The method of claim 13, further comprising debriding the tissue to be debrided for more than two days. 16. The method of claim 13, wherein applying the hydrogel to the portion of the tissue site comprises applying a hydrogel from a tube. 17. A reduced-pressure wound dressing comprising: a hydrogel adapted to cover a treatment area of a tissue site, wherein the hydrogel comprises a blocked acid debriding agent comprising an alpha hydroxy acid bound to a blocking material;a manifold adapted to cover the hydrogel and distribute reduced pressure to the tissue site; anda sealing drape for placing over the tissue site and manifold, the sealing drape adapted to form a fluid seal over the tissue site and manifold. 18. The reduced-pressure wound dressing of claim 17, further comprising an intermediate foam layer between the hydrogel and the manifold. 19. The reduced-pressure wound dressing of claim 17, wherein the blocked acid debriding agent comprises lactic acid and arginine. 20. The reduced-pressure wound dressing of claim 17, wherein the blocked acid debriding agent comprises glycolic acid and arginine. 21. The reduced-pressure wound dressing of claim 17, wherein the hydrogel is adapted to soften and break apart over time in response to exposure to wound fluid. 22. The reduced-pressure wound dressing of claim 17, wherein the manifold is adapted to absorb the hydrogel after the hydrogel softens. 23. The reduced-pressure wound dressing of claim 17, wherein the manifold is adapted to absorb debrided necrotic tissue. 24. The reduced-pressure wound dressing of claim 17, wherein the hydrogel is a preformed sheet. 25. The reduced-pressure wound dressing of claim 17, wherein the hydrogel is a viscous gel.
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