A delivery device is provided which has a container containing a dose of a powder, a chamber adapted to receive the container, at least one gas inlet by which gas may enter the chamber, and at least one gas outlet by which gas and entrained powder may exit the chamber for inhalation. The delivery de
A delivery device is provided which has a container containing a dose of a powder, a chamber adapted to receive the container, at least one gas inlet by which gas may enter the chamber, and at least one gas outlet by which gas and entrained powder may exit the chamber for inhalation. The delivery device has a pre-use configuration in which the container is accommodated, at least partially, within a storage enclosure in a wall of the chamber. The delivery device has a deployment member adapted to put the delivery device in an operative configuration by displacing the container from the storage enclosure into the chamber, such that the container is movable within the chamber, in use, the deployment member being adapted to at least partially occupy the storage enclosure in the operative configuration.
대표청구항▼
1. A delivery device comprising: a container containing a dose of powder and having a preformed opening;a chamber adapted to receive the container;at least one gas inlet in a side wall of the chamber by which gas may enter the chamber;at least one gas outlet by which gas and entrained powder may exi
1. A delivery device comprising: a container containing a dose of powder and having a preformed opening;a chamber adapted to receive the container;at least one gas inlet in a side wall of the chamber by which gas may enter the chamber;at least one gas outlet by which gas and entrained powder may exit the chamber for inhalation;a sleeve extending from an end of the side wall of the chamber and having an opening into the chamber; anda deployment member configured to move the delivery device from a pre-use configuration to an operative configuration, wherein: in the pre-use configuration, the container is accommodated, at least partially, within the sleeve and the deployment member has an end wall positioned within the sleeve;the deployment member adapted to put the delivery device in the operative configuration by displacing, with the end wall, the container from the sleeve into the chamber, such that all of the container is released into the chamber with the end wall positioned in the opening into the chamber in the operative configuration to form a surface of the chamber;the container being a free standing structure with a central axis, the container being freely movable within the chamber in the operative configuration by gas flow generated by the inhalation of a patient or by gas flow generated by a gas source, releasing the powder through the preformed opening with the container remaining intact in the operative configuration; andthe at least one gas inlet is positioned so that, in use, the gas flow in the chamber drives the central axis of the container in an orbital motion around a central axis of the chamber while a perimeter of the container always surrounds the central axis of the chamber. 2. The delivery device as claimed in claim 1, wherein the deployment member is movably mounted relative to the chamber, such that the end wall of the deployment member contacts the container in the sleeve in the pre-use configuration, and urges the container into the chamber on movement from the pre-use configuration to the operative configuration. 3. The delivery device as claimed in claim 1, wherein the deployment member is retained in the pre-use configuration by retaining formations adapted to maintain the deployment member in the pre-use configuration during normal handling. 4. The delivery device as claimed in claim 1, wherein an entire length of the sleeve is occupied by the deployment member in the operative configuration such that the gas flow within the chamber, in use, is not adversely affected by the presence of a void space within the sleeve. 5. The delivery device as claimed in claim 1, wherein the deployment member is retained in the operative configuration by retaining formations. 6. The delivery device as claimed in claim 5, wherein the retaining formations have the form of a cooperating projection and recess. 7. The delivery device as claimed in claim 5, wherein the delivery device is a single-use, disposable device, and the retaining formations are adapted to prevent further movement of the deployment member, without damaging the delivery device. 8. The delivery device as claimed in claim 1, wherein the deployment member defines at least part of an inhalation passageway of the delivery device, through which gas and entrained powder are inhaled by a patient. 9. The delivery device as claimed in claim 8, wherein the inhalation passageway defined by the deployment member extends from the end wall in which the at least one gas outlet is formed. 10. The delivery device as claimed in claim 8, wherein the deployment member also comprises a mouthpiece or a nosepiece, through which gas and entrained powder are withdrawn from the delivery device, in the operative configuration. 11. The delivery device as claimed in claim 1, wherein a seal is formed between an exterior surface of the deployment member and an interior surface of the sleeve, such that gas and entrained powder does not leak into the sleeve during use. 12. The delivery device as claimed in claim 1, wherein the deployment member is moveably mounted within the sleeve, and the deployment member is received within the sleeve to a greater extent in the operative configuration, relative to the pre-use configuration. 13. The delivery device as claimed in claim 12, wherein the deployment member includes indications that are visible in the pre-use configuration, and hidden in the operative configuration by the sleeve, in order to indicate a status of the delivery device. 14. The delivery device as claimed in claim 1, wherein the container is compliant. 15. The delivery device as claimed in claim 1, wherein an interior surface of the sleeve comprises a resilient portion. 16. The delivery device as claimed in claim 1, wherein the container comprises one or more additional preformed openings for dispensing the dose from the container. 17. The delivery device as claimed in claim 1, wherein the container is formed of a number of cooperating components, wherein the preformed opening is defined between the cooperating components. 18. The delivery device as claimed in claim 1, wherein the preformed opening is integrally formed with the container. 19. The delivery device as claimed in claim 1, wherein the preformed opening is closed by a closure member in the pre-use configuration. 20. A method of delivering a powder, comprising using the delivery device as claimed in claim 1. 21. A method of treatment of a patient with a respiratory disorder, comprising administering at least one powdered medicament using the delivery device as claimed in claim 1. 22. The delivery device as claimed in claim 1, wherein the at least one gas inlet comprises a tangential arrangement of at least one gas inlet slot causing gas drawn into the chamber to be directed around a circumference of the chamber such that the gas flow comprises a rotating body of gas within the chamber that drives the motion of the container. 23. The delivery device as claimed in claim 1, wherein the orbital motion is accompanied by rotation of the container about its central axis. 24. A delivery device comprising: a discrete container containing a dose of powder and having a preformed opening;a chamber adapted to receive the container;at least one gas inlet in a side wall of the chamber by which gas may enter the chamber;at least one gas outlet by which gas and entrained powder may exit the chamber for inhalation;a sleeve extending from the chamber; anda deployment member accommodated in the sleeve through an end of the sleeve opposite the chamber, wherein: in a pre-use configuration, an end wall of the deployment member is positioned within the sleeve between a distal end of the sleeve and a chamber end of the sleeve and is in contact with the container;in an operative configuration, the end wall of the deployment member is positioned flush with a chamber end of the sleeve, such that all of the container is released into the chamber, to form a surface of the chamber within which the container is confined;the container being a free-standing structure with a central axis, the at least one gas inlet positioned so that, in use, the gas flow in the chamber drives the central axis of the container in an orbital motion around a central axis of the chamber while a perimeter of the container always surrounds the central axis of the chamber. 25. The delivery device as claimed in claim 24, wherein the deployment member is retained in the pre-use configuration by retaining formations adapted to enable movement of the deployment member into the operative configuration, but prevent other movement, without damaging the delivery device.
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이 특허에 인용된 특허 (7)
Hallworth Gerald W. (Ware GB2) Clough David (Bishop Stortford GB2), Device for dispensing medicaments.
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