A method of imaging an interior of an eye includes illuminating the interior of the eye with one or more beams of light from a light source, and said illuminating is configured to trigger a change to a pupil of the eye. An image sensor captures a sequence of images of light reflected by the interior
A method of imaging an interior of an eye includes illuminating the interior of the eye with one or more beams of light from a light source, and said illuminating is configured to trigger a change to a pupil of the eye. An image sensor captures a sequence of images of light reflected by the interior of the eye during an expected timeframe when a width of the pupil is changing in response to said illuminating. A processing apparatus combines images in the sequence of images to form a composite image having a larger depth of field than a depth of field of each of the images in the sequence of images. The depth of field for each of the images corresponds to the width of the pupil when each of the images is captured.
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1. A method of imaging an interior of an eye, comprising: illuminating the interior of the eye with one or more beams of light from a light source, wherein said illuminating is configured to trigger a change to a width of a pupil of the eye;capturing, with an image sensor, a sequence of images of li
1. A method of imaging an interior of an eye, comprising: illuminating the interior of the eye with one or more beams of light from a light source, wherein said illuminating is configured to trigger a change to a width of a pupil of the eye;capturing, with an image sensor, a sequence of images of light reflected by the interior of the eye during an expected timeframe when the width of the pupil is changing in response to said illuminating, wherein the pupil is leveraged as an imaging aperture for the image sensor that increases the depth of field of images of the retina in the sequence of images as the pupil shrinks in response to the illuminating; andcombining, with a processing apparatus, the images in the sequence of images to form a composite image having a larger depth of field than a depth of field of each of the images in the sequence of images, wherein the depth of field for each of the images is influenced by the width of the pupil when each of the images is captured. 2. The method of claim 1, wherein illuminating the interior of the eye includes changing, with the processing apparatus, a level of illumination output from the light source, and wherein capturing the sequence of images includes capturing the sequence of images as the level of illumination output from the light source changes, wherein the width of the pupil changes in response to changing the level of illumination. 3. The method of claim 1, further comprising removing, with the processing apparatus, a first set of images from the sequence of images, wherein the first set of images are not used to form the composite image. 4. The method of claim 3, wherein the first set of images includes at least one of: overexposed images having a luminance value greater than a first threshold luminance value; andunderexposed images having the luminance value less than a second threshold luminance value. 5. The method of claim 1, further comprising blocking, with an aperture disposed between the eye and the image sensor, at least some of light reflected off of a cornea of the eye from reaching the image sensor. 6. The method of claim 1, wherein the image sensor captures the sequence of images at a frame rate of at least 200 frames per second, and wherein the sequence of images includes at least 10 images. 7. The method of claim 1, wherein combining the images includes the processing apparatus using a focus stacking algorithm, wherein in-focus portions of the images are identified using at least one of edge detection, feature detection, or Fourier analysis, and wherein the in-focus portions of the images are combined to form the composite image. 8. The method of claim 1, wherein illuminating the interior of the eye with the one or more beams of light includes using a substantially collimated beam of light emitted from at least one of a light emitting diode or a laser diode included in the light source. 9. The method of claim 8, wherein illuminating the interior of the eye with the one or more beams of light includes illuminating one or more points on the retina, wherein the substantially collimated beam of light is formed using at least one of an aperture or lens optics. 10. The method of claim 1, wherein the pupil is not chemically dilated while capturing the sequence of images, wherein the light source includes a plurality of light emitting diodes or a plurality of laser diodes. 11. A system for imaging a retina in an eye, comprising: a light source positioned to illuminate the retina with one or more beams of light;an image sensor positioned to receive light reflected off of the retina, and capture a sequence of images including images of the retina as a width of a pupil of the eye is changing;an aperture shaped and positioned to block at least some light reflected off of a cornea of the eye from reaching the image sensor; anda processing apparatus, communicatively coupled to the image sensor to receive the sequence of images, wherein the processing apparatus includes logic that when executed by the processing apparatus causes the processing apparatus to perform operations including: combining images in the sequence of images to form a composite image having a larger depth of field than a depth of field of each of the images in the sequence of images, wherein the depth of field of each of the images is influenced by the width of the pupil when each of the images is captured such that the pupil is leveraged as another aperture of the system that increases the depth of field of the images of the retina in the sequence of images as the pupil shrinks in response to illumination from the light source. 12. The system of claim 11, wherein the processing apparatus is further coupled to the light source, and wherein the processing apparatus further includes logic that when executed by the processing apparatus causes the processing apparatus to perform operations including: changing a level of illumination output from the light source and directed toward the retina; andcapturing the sequence of images with the image sensor as the level of illumination output from the light source changes, wherein each of the images in the sequence of images have different depths of field. 13. The system of claim 12, wherein the different depths of field of the images are in response to the width of the pupil in the eye increasing or decreasing in size from changing the level of illumination from the light source, and wherein changing the level of illumination includes changing at least one of: an on-time of the light source, an intensity of the one or more beams of light output from the light source, a pattern of the one or more beams of light configured to elicit a pupil response, or color distribution of the one or more beams of light. 14. The system of claim 11, wherein the processing apparatus further includes logic that when executed by the processing apparatus causes the processing apparatus to perform operations including: removing a first set of images from the sequence of images prior to combining the images in the sequence of images. 15. The system of claim 14, wherein the first set of images includes at least one of: overexposed images having a luminance value greater than a first threshold luminance value; orunderexposed images having the luminance value less than a second threshold luminance value. 16. The system of claim 11, wherein the light source includes a plurality of light emitting diodes (LEDs), and wherein each of the LEDs the plurality of LEDs is respectively located in different locations, relative to the eye, each of the LEDs to shine a beam of light on a different location of the retina. 17. The system of claim 11, wherein the image sensor captures the sequence of images at a frame rate of at least 200 frames per second, and wherein the sequence of images includes at least 10 images. 18. The system of claim 11, further comprising: a display coupled to the processing apparatus to display an image positioned for the eye to see while the one or more beams of light illuminate the retina;intermediate optics disposed between the image sensor and the aperture, wherein the intermediate optics include at least one of a lens or a beam splitter. 19. The system of claim 18, wherein the light source emits infrared light, and wherein each of the images in the sequence of images have different depths of field in response to the width of the pupil in the eye increasing or decreasing in size from changing the image on the display. 20. The system of claim 11, wherein the on-time of the light source is less than an integration time of the image sensor during capture of each of the images, or wherein the integration time of the image sensor is less than the on-time of the light source during capture of each of the images. 21. The system of claim 20, wherein the on-time of the light source is less than 50% of the integration time. 22. The system of claim 11, wherein a total integration time of the image sensor to capture the sequence of images is greater than a total on-time of the light source when illuminating the retina.
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