[보고서]기능성식품신소재개발센터

보고서 정보

주관연구기관

고려대학교 산학협력단

보고서유형

최종보고서

발행국가

대한민국

언어

한국어

발행년월

2012-04

과제시작연도

2009

주관부처

보건복지가족부
Ministry for Health, Welfare and Family Affairs

등록번호

TRKO201200007553

과제고유번호

1355060290

사업명

보건의료기술연구개발

DB 구축일자

2013-05-20

키워드

기능성 식품.천연소재.조직특이유전.functional foods.natural products.cell-specific promoters.

DOI

https://doi.org/10.23000/TRKO201200007553

표 [(a) control, (b) HC3, (c) EC3, (d) CC3, (e) HB3, (f) EB3, (G) CB2]은 polymer-coated 및 polymer-blended algiante microsphere에 대한 surface morphology를 나타냄.
표 Cytotoxicity of Allium victorialis subsp. Platyphyllum extracts for human umbilical vein endothelial cell.
표 Scheme of synthesis of N-acyl chitosans
표 1H NMR spectra of chitosan (a) and N-acyl chitosan (b) (C12) in CD3COOD/D2O.
표 Scanning electron micrographic photographs of lauroyl chitosan nanoparticle (C12).
표 Mean particle size of the protein loaded N-acyl chitosan nanoparticles at the concentration of BSA (0.1mg/mL)
표 Mean particle size (nm) of the protein loaded N-acyl chitosan nanoparticles at the various concentrations of BSA
표 BSA loading efficiency of N-acyl chitosan nanoparticles with the concentration of BSA and hydrophobic side chain.
표 Characterizations of N-acyl chitosans and ascorbic acid loaded N-acyl chitosan nanoparticles
표 FT-IR spectrum of ascorbic acid loaded stearoyl chitosan nanoparticle (C18).
표 Scanning electronic micrographs of chitosan coated and non-coated liposomes.
표 The zeta potential of liposomes.
표 Loading efficiency and payload of VE loaded liposomes prepared with 70mg to 90mg VE and 100mg different ratio of pc and chol.
표 The loading efficiency and payload of chitosan coated liposomes using direct injection method with different solvent system.
표 Different ratios of pc and chol effect on the payload of CPT loaded to the nanoliposomes using direct injection method with ethanol & ether solvent system
표 Different ratios ofpc and chol effect on the loading efficiency of CPT to the nanoliposomes using direct injection method with ethanol & ether solvent system
표 Different ratios of pc and chol effect on the payload of CPT loaded to the nanoliposomes using film loading method
표 Different ratios of pc and chol effect on the payload of CPT loaded to the nanoliposomes using film loading method
표 The highest loading efficiency and payload of direct injection and film loading method.
표 In vitro release of the ascorbic acid from N-acyl chitosan nanoparticles at pH 1.3. and pH 7.4.
표 SEM photo of gentamicin loaded lauroyl chitosan nanoparticles (C12)
표 Encapsulation efficiency of gentamicin in N-acyl chitosan nanoparticles.
표 In vitro release of the gentamicin from N-acyl chitosan nanoparticles at pH 1.3 (a) and pH 7.4.(b).
표 Cryo-TEM micrographs of chitosan coated and non-coated liposomes.
표 Different ratios of pc and chol and different concentration of chitosan solution effect on the size of liposomes
표 different initial mass of Vitamin C effect on the loading efficiency and payload
표 different ratio of pc and chol effect on the loading efficiency and payload of Vitamin C loaded liposomes
표 Storage stability of Vitamin C loaded liposomes with different concentration of chitosan solutions
표 Different concentration of chitosan solution effect on the loading efficiency and payload of Vitamin C loaded liposomes
표 In vitro inhibitory effects of cell spent culture supernatants (SCS), and precipitants of L. casei ATCC 393 on the growth of H. pylori KCTC 12083.
표 Loading efficiency of chitosanpoly- γ – glutamic acid microsphere loaded peptides from Lactobacillus casei ATCC 393 at different molar ratio by-NH3+ on chitosan and -COO- on poly- γ –glutamic acid.
표 In vitro release study of peptide produced by Lactobacillus casei ATCC 393(393 peptide) from chitosan - poly- γ – glutamic acid microspheres in enzyme free - simulated gastric fluid(SGF, pH1.5).
표 Inhibitory activities of non-encapsulated ( ) and encapsulated 393 precipitants (■) after SGF treatment on the adhesion of H. pylori to the gastric carcinoma cell line AGS.
표 In vitro inhibitory action of non-encapsulated Lactobacillus casei ATCC 393(393 peptide) (■) and encapsulated 393 peptides( ) on the growth of H. pylori KCTC 12083 in enzyme free- simulated gastric fluid(pH 1.5).
표 TNBS Value and Zeta potential of both native and aminated gelatin solution (n=3)
표 SEM photograph of gelatin microspheres loading amoxicillin and crosslinked fucoidan.
표 Fig. 2. Release profile from aminated gelatin microparticles crosslinked with different concentration fucoidan in phosphate buffered saline (a, pH 7.4) and simulated gastric fluid
표 Absorbance of uncrosslinked amino groups in the different gelatin microsphere samples was measured by UV spectrophotometer at 335nm.
표 Loading efficiency of gelatin microsphere with crosslinked different concentration of fucoidan.
표 Fluorescence intensity of microspheres remaining stomach epithelial mucus in mouse.
표 Pictures of gastric mucoadhesion of microparticles in isolated and perfused rat stomach.
표 In vitro inhibitory zone of gelatin microspheres cross-linked different concentration of fucoidan on the growth of H. pylori KCTC 12083.
표 The schema of liposome, nano liposome that was coated by chitosan and alginic acid.
표 The effect of sonication time (2, 3, 4, 5, and 6min) on the mean size of prepared nano carrier systems (n=5), (Chitosan M.W. 3,000Da, 0.1%, W/V; lecithin : cholesterol = 6 : 4)
표 The effect of molecular weight and concentration of primary coating material (chitosan) on the mean size of prepared nano carrier systems containing etofenprox or alpha-cypermethrin (n = 5) (lecithin : cholesterol = 6 : 4)
표 The effect of the number of coating layers and concentration of coating materials on the mean size of nano carrier systems (n=5),
표 The effect of the concentration of primary and secondary coating materials on the surface charge of prepared nano carrier systems (n=5),
표 Figure 7. The effect of the concentration of primary and secondary coating materials on the encapsulation efficiency of prepared nano carrier systems
표 The effect of molecular weight and concentration of chitosan on release profile of primary coated nano liposome contening functional ingredient molecules as a core material
표 Scanning electron micrographs of M.W. 3,000, 0.3%, W/V chitosan-coated nano liposome containing functional ingredient molecules.
표 The schema of liposome, nano liposome that was coated by chitosan
표 The different chitosan samples and their surface charge values (n=15)
표 The surface charge of non-coated liposomes
표 The effect of the kind of chitosan sample and its concentration and the kind of preparation method on the mean size of chitosan-coated nano-liposomes (n = 5) (used high voltage (in electrospraying) in the combined method; 17 kV, initial homogenization time in U.H.
표 The effect of the kind of chitosan sample and preparation method on the surface charge of prepared nano-liposomes (n = 5) (chitosan concentration, 0.1%,
표 The effect of chitosan concentration and the kind of preparation method on the surface charge of prepared nano-liposomes
표 (6-A) Scanning electron micrographs of 0.3%, w/v chitosan A-coated nano-liposomes on the red pepper plant (the ultrasonic homogenization method),
표 The effect of chitosan concentration and the kind of preparation method on the encapsulation efficiency of c h i t o s a n - c o a t e d nano-liposomes containing etofenprox
표 (a) FT/IR spectra; (b) 1H NMR of HA and HA-GMS.
표 Droplet size and polydispersity index of HA-GMS-free anoemulsions.
표 CLSM of HA-GMS nanoemulsion (1 mg/mL) in methylene chloride/water/T80?.
표 Droplet size of HA-GMS nanoemulsions (1 mg/mL) in methylene chloride/water/T80?.S20 system as a function of storage time.
표 TEM of HA-GMS nanoemulsion (1 mg/mL) in methylene chloride/water/T80?.S20 system.
표 그림 1. 클로렐라 추출물 액상 제품 및 분말 제품 제조방법
표 강제수영부하 실험시 클로렐라의 부동시간 감소 효과
표 혈액관련 지표에 대한 클로렐라의 효과
표 Effect of Hyunhosaek on NO synthesis in IFN-γ-stimulated macrophages
표 Effect of Hyunhosaek on iNOS expression in IFN-γ-treated macrophages
표 Isolation and identification of compounds
표 Effect of Ikmocho on NO & TNF-α production in macrophages
표 Effect of Ikmocho on NF-κB expression in macrophages
표 Effect of Ikmocho on NO & TNF-α mRNA expression in macrophages
표 Effect of Dokwhal on NO production in macrophages
표 Effect of Susemi on forced swimming-induced immobility in mice
표 Effect of EGCG on cytokine production and expression in U373MG cells
표 Effect of EGCG on PGE2 production and COX-2 expression in IL-1β plus Aβ (25-35) -stimulated U373MG cells
표 Effect of EGCG on cytokine production and expression in U373MG cells
표 Effect of EGCG on NF- B &I B expression in IL-1 plus κ κ β Aβ (25-35) -stimulated U373MG cells
표 Effect of EGCG on MKP-1 expression in U373MG cells
표 Effect of scopoletin on survival and degranulation of mast cells
표 Effect of scopoletin on PMA plus A23187-induced cytokines mRNA expression
표 Effect of scopoletin on PMA plus A23187-induced NF-κB activation and IκBα phosphorylation and degradation
표 Dose-dependent effects of GH on NO inhibition in rIFN/LPS-treated peritoneal macrophages
표 Effects of GH on the expression of iNOS in rIFN/LPS-treated peritoneal macrophages
표 Effects of GH on the rIFN/LPS-induced IL-12p70 production in peritoneal macrophages.
표 Chemical Structure of Compounds 1-3 isolated from Allium victorialis
표 1H-NMR Spectrum of Compound 1
표 13C-NMR Spectrum of Compound 1
표 1H-NMR Spectrum of Compound 2(DMSO-d6, 300 MHz)
표 1H-NMR Spectrum of Compound 3
표 EI-MS spectrum of Compound 3
표 1H-NMR Spectrum of Compound 3(CDCl3, 300 MHz)
표 13C-NMR Spectrum of Compound 3
표 1H-1H COSY Spectrum of Compound 3
표 HMQC Spectrum of Compound 3
표 산마늘 추출물의 free radical scavenging 효과
표 산마늘 추출물의 추출 부위별 reducing power 활성
표 산마늘 추출물의 부위별 세포독성
표 산마늘 부위별 추출물의 Helicobacter pylori의 생육저해.
표 산마늘 추출물의 Cell adhesion 저해효과
표 Effects of Allium victorialis subsp.
표 Cytotoxicity of Allium victorialis subsp. Platyphyllum extracts for human umbilical vein endothelial cell.
표 Influence of Allium victorialis subsp. Platyphyllum extracts on TNF-induced mRNA expression of all 3 adhesion molecules.
표 Inhibitory effects of Allium victorialis subsp.
$Effects of ethyl acetate fractions of leaf and stem, and chloroform fraction on washed rabbit platelet aggregation in vitro.$ 표 Effects of ethyl acetate fractions of leaf and stem, and chloroform fraction on washed rabbit platelet aggregation in vitro.
$Inhibitory effects of various fractions from Allium victorialis var. platyphyllum on 5% FBS-stimulated VSMCs proliferation.$ 표 Inhibitory effects of various fractions from Allium victorialis var. platyphyllum on 5% FBS-stimulated VSMCs proliferation.
표 클로렐라 원말 추출물 및 음료제품 OD200 의 UV결과
표 클로렐라 원말 추출물 및 OD 200 제품의 CGF분석
표 HPLC profile of standard mixture (chlorophyll a, chlorophyll b, pheophorbide and β -carotene) (A), Chlorella (B) and Chlorella extract (C).
표 GC-MS chromatograms of Chlorella extract.
표 HPLC-UV chromatograms of standard mixture (nucleoside, mono-, di- and tri-nucleotides) (A), Chlorella extract (B) and Chlorella extract with enzyme-treatment (C).
표 HPLC-UV chromatograms of standard 16 mixture
표 HPLC-UV chromatograms of Chlorella extract with enzyme-treatment
표 HPLC-UV chromatograms of standard 16 mixture
표 HPLC-UV chromatograms of Chlorella extract with enzyme-treatment
표 HPLC-UV chromatograms of Chlorella extract product (OD200) with enzyme-treatment
표 Yield (%) of Allium victorialisleaves extracts under different extract solventratio.
표 Total phenolic contents (mg/g extract) of Allium victorialis leaves extracts under different extract solvent ratio
표 Total flavonoid contents (mg/g extract) of Allium victorialisleaves extracts under different extract solvent ratio.
표 Representative HPLC chromatograms of quercetin (A) and kaempferol (B) (external standards) and separated at 260nm using the 30% MeOH (with formic acid): 100% MeOH gradient method.
표 HPLC Chromatograms of 70% EtOH extract of Allium victorialis leaves monitored at 256nm (A) Quercetin, (B) Kaempferol.
표 HPLC Chromatograms of 70% EtOH extract of Allium victorialis leaves monitored at 260nm (A) Quercetin, (B) Kaempferol.
표 HPLC Chromatograms of 70% EtOH extract of Allium victorialis leaves monitored at 280nm (A) Quercetin, (B) .
표 HPLC Chromatograms of 70% EtOH extract of Allium victorialis leaves monitored at 380nm (A) Quercetin, (B) Kaempferol.
표 HPLC Chromatograms of 70% EtOH extract of Allium victorialis leaves monitored at 325nm (A) Quercetin, (B) Kaempferol.
표 Quercetin levels in Allium victorialis leaves extracts (0~100% EtOH) at 256, 260, 280, 320, 380nm.
표 Keampferol levels in Allium victorialis leaves extracts (0~100% EtOH) at 256, 260, 280, 320, 380nm.
표 HPLC chromatograms of trans-resveratrolrecordedat300nm.
표 Comparison of total phenolic contents, total flavonoid contents and total anthocyanin contents
표 HPLC chromatograms of anthocyanins recorded at 520 nm.
표 Anthocyanins and trans-resveratrol of the wine and NWCP
표 Comparison of DPPH fee radical scavenging activity and ABTS radical scavenging activity of samples and standard antioxidant compounds such as α-tocopherol,
표 Reducing power of samples and standard antioxidant compounds such as α -tocopherol, ascorbic acid, trolox, BHA and BHT.
표 HPAEC를 이용한 GBE의 당전이반응 산물 분석.
표 분지올리고당에 고정화효모를 처리하기 전과 후의 성분을 HPAEC를 이용한 분석.
표 최적효소농도에서의 분지올리고당 반응 산물의 HPAEC 분석.
표 최적효소농도에서 22시간 반응 후 분지올리고당의 성분 분석
표 고정화효모를 처리하여 얻은 고순도 분지올리고당의 성분 분석
표 HA 생산을 위한 발효 및 정제공정
표 살균 온도 및 시간에 따른 미생물 수 변화
표 마이크로웨이브 처리에 따른 미생물 수 변화
표 감마선 처리에 의한 따른 미생물 수 변화
표 Variation of exponents a,b and c with scale
표 Summary of purification of neutral protease(NPR 68) and alkaline protease(APR68) from B. amyloliquefaciens FSE-68
표 Summary of purification of neutral protease(NPR 68) and alkaline protease(APR68) from B. amyloliquefaciens FSE-68 9)
표 HPAEC를 이용한 분지올리고당의 분석.
표 HPAEC를 이용한 분지올리고당의 성분 분석
표 MALDI-TOF/MS를 이용한 환상아밀 로스 반응생성물의 분자량 분석
표 HPAEC를 이용한 반응시간에 따른 Pf αGT와 amylose의 반응산물 분석
표 maltose와 β-CD를 기질로 한 TreX의 시간에 따른 반응산물 TLC 분석
표 TLC를 이용한 TreX와 G2-β-CD 반응 생성물의 TLC 분석
표 살균 온도 및 시간에 따른 미생물 수 변화
표 NaOCl 처리 농도와 시간에 따른 미생물 수 변화
표 포르말린 농도에 따른 미생물 수 변화
표 에탄올 농도 및 가온 온도에 따른 미생물 수 변화
표 Digest profiles of soy protein hydrolysates of APR or NPR with DH (%) ranging 7 through 25% determined by gel permeation chromatography
표 ACE inhibition activity of soy protein isolate hydrolysates by Npr68, Apr68 from B. amyloliquefaciens FSE68 and trypsin.
표 Saltiness and bitternessof DH15% Npr68 and Apr68 hydrolysates.
표 Contents and yields of solid of hydrolysates by Npr68 and Apr68
표 Sweetness and sournessof DH15% Npr68 and Apr68 hydrolysates..
표 Sensory test summary of Npr68 and Apr68 hydrolysates.
표 Discriminative test of antihypertensive peptide beverages containing soybean hydrolysate by Npr68.
표 Discriminative test of antihypertensive peptide beverages containing soybean hydrolysate by Apr68.
표 표본의 인적 특성
표 체질에 대한 일반적인 의식
표 응답자의 체질 분포
표 본인의 체질을 알게된 경위(성별)
표 본인의 체질을 알게된 경위(연령별)
표 음식섭취시 체질의 고려여부
표 HPAEC를 이용한 환상아밀로스 의 분석
표 MALDI-TOF/MS를 이용한 TSαGT와 아밀로스의 반응산물 분석.
표 TreX를 이용하여 maltosyl-β-CD로부터 dimaltosyl-β-CD 생산 반응 메카니즘
표 TreX를 이용한 dimaltosyl-β-CD 생산 시 두 가지 기질 조건에 대한 최대 수율
표 maltosyl-β-CD를 기질로 할 때 β-CD의 TreX에 대한 활성저해효과 kinetic parameter
표 5% maltotriose를 기질로 한 MGase 반응산물의 TLC분석.
표 5% maltotriose를 기질로 한 MGase의 당전이 반응 기작
표 MGase를 이용하여 LCS로 부터 생산한 분지올리고당의 HPAEC 분석
표 신규조성 분지올리고당의 성 분비 (%).
표 BSMA의 아밀로스에 대한 선택적 분해 기작. 수많은 가지결합을 가지고 있어 아밀로스에 비해 상대적 으로 너무 큰 아밀로펙틴은 BSMA의 dimer가 이루는 좁은 active site에 쉽 게 도달하지 못함.
표 BSMA 처리 후 각 전분의 아밀로스 및 아밀로펙틴 함량
$Purification of antioxidant peptides from soy protein hydrolysate. C, D, and F stand for the separated fractions of F26-19showing high antioxidant activity.$ 표 Purification of antioxidant peptides from soy protein hydrolysate. C, D, and F stand for the separated fractions of F26-19showing high antioxidant activity.
표 Sequences and origin of antioxidant peptides obtained by RP C18 and identified by LC/MS and MS/MS
표 Viability of TM 4 cells treated with MEHP alone or in combination with synthetic peptides. Legends are V, vehicle
표 Lipid peroxidation levels in the TM4 cells treated with MEHP alone or the mixture of MEHP and synthetic pepdides or tocopherol.
표 Intensity-density plots of raw data (A) and after Background correction (B),
표 Unsupervised hierarchical clustering and self organizing maps
표 Blood glucose (A), insulin (B), total cholesterol (C) and triglyceride (D) levels of db/db mice. *, P-value<0.05
표 MvA plots of raw data (A) and after Background correction (B), Within array normalization (C), and Between array normalization (D)
표 Intensity-density plots of raw data (A) and after Background correction (B), Within array normalization (C), and Between array normalization (D)
표 SAM plot
표 Upregulated pathways in db/db mice compared to C57BL/6 mice, *, P-value<0.05
표 Down-regulated pathways in db/db mice compared to C57BL/6 mice. *, P-value<0.05
표 Significant genes produced by SAM
표 Upregulated genes involved in lipid catabolism in db/db mice
표 Downregulated genes involved in gluconeogenesis, glycogen metabolism and lipid metabolism in db/db mice
표 Blood glucose and triglyceride levels in HBCD-feeding db/db mice
표 Area under curve (AUC) in OGTT test in HBCD-feeding db/db mice
표 SAM plot
표 Up-regulated pathways in HBCD-feeding db/db mice
표 Significant genes produced by SAM
표 Up-regulated genes involved in glucose and lipid metabolism in HBCD-feeding db/db mice
표 Down-regulated pathways in HBCD-feeding db/db mice.
표 Comparison of control and HBCD feeding db/db in pathway analysis
표 Haematoxylin and eosin (H&E) stain of a section of liver showing the histologic appearance of hepatic fatty change.
표 The amounts of feed intake of C57BL/6 male mice during experimental period.
표 Haematoxylin and eosin (H&E) stain of a section of small intestine.
표 Liver injury test. Serum was collected from C57BL/6 male mice and tested for AST and ALT enzyme activity.
표 Plasma total cholesterol levels (mg/dl).
표 Effects of lactic acid bacteria species on plasma free cholesterol.
표 Effects of lactic acid bacteria species on plasma cholesteryl ester. Data are means ± S.E.M.
표 Effects of lactic acid bacteria species on plasma LDL cholesterol. Data are means ± S.E.M.
표 Effects of lactic acid bacteria species on plasma HDL cholesterol.
표 Effects of lactic acid bacteria species on plasma triglyceride. Data are means ± S.E.M.
표 Effects of lactic acid bacteria species on plasma phospholipids.
표 Content of bile acids in stool from C57BL/6 male mice fed various diets.
표 Liver lipid concentration were determined from C57BL/6 male mice after lactic acid bacteria administration.
표 Cytokine expression profile after administered LAB for 4 weeks.
표 Alterations in mean body weight of the C57BL/6 male mice after LAB administration.
표 The amounts of feed intake of C57BL/6 male mice during experimental period (g/head)
표 Haematoxylin and eosin (H&E) stain of a section of liver showing the histologic appearance of hepatic fatty change.
표 Haematoxylin and eosin (H&E) stain of a section of small intestine.
표 Liver injury test.
표 Plasma total cholesterol levels (mg/dl).
표 Effects of lactic acid bacteria species on plasma free cholesterol.
표 Effects of lactic acid bacteria species on plasma cholesteryl ester. Data are means ± S.E.M.
표 Effects of lactic acid bacteria species on plasma LDL cholesterol. Data are means ± S.E.M.
표 Effects of lactic acid bacteria species on plasma HDL cholesterol.
표 Effects of lactic acid bacteria species on plasma triglyceride.
표 Effects of lactic acid bacteria species on plasma phospholipids.
표 Liver lipid concentration were determined from C57BL/6 male mice after lactic acid bacteria administration.
표 Production of cytokines by feeding LAB for 4 weeks.
표 Growth curve and enzyme activity curve of Bacillus amyloliquefaciens FSE-68.
표 Summary of purification of enzyme from B.amyloliquefaciensFSE68
표 Hydrolysis conditions of isolated soy protein by Npr68 and Apr68.
표 Analysis of soymilk beverage after fermentation
표 Contents and yields of solid of hydrolysates by enzyme
표 Sensory evaluation of soymilk beverage according to addition of different ISP hydrolysates
표 LCS농도에 따른 특수분지올리고당 수율 변화 및 성분 분석
표 MGase 농도에 따른 특수올리고당 수율의 변화 및 성분 분석
표 BSMA를 이용한 타피오카 전분의 아밀로스 함량조절.
표 HPLC를 이용한 칡 이소플라본 추 출물의 분석.
표 순수정제 한 물질 (1)의 TLC 분석.
표 물질 (1)의 MALDI-TOF/MS 분석.
표 칡전분을 기질로 한 다양한 효소의 가수분해 반응 분석.
표 BSMA 반응 칡가루의 이소플라본 성분변화 분석.
표 Effect of L. plantarum administration on LDL receptor, HMG-CoA reductase, CYP7A1, and CYP27A1 gene expression in C57BL/6 mice.
표 Effect of L.plantarum administration on the protein levels of the LDL receptor, HMG-CoA reductase, CYP7A1 and CYP27A1 in C57BL/6 mice.
표 HPLC (A) 와 HPAEC (B)를 이용한 G1-puerarin 효소 반응액의 분석
표 BSMA를 이용한 puerarin당전이 산물의 생산
표 Maltogenic amylase와 glucanotransferase를 이용한 cycloamylose-purarin complex생산
표 HPLC와 TLC를 이용한 효소반응 단계별 생성물 분석
표 T2-1의 MALDI-TOF MS로 분석 결과
표 TLC를 이용한 추출물의 분석
표 HPLC를 이용한 조성물 내의 퓨라린 및 이소플라본 함량 측정
표 퓨라린 섭취가 혈중 에스트로겐 농도에 미치는 영향
표 HPLC를 이용한 조성물 내의 퓨라린 및 이 소플라본 함량 정량
표 4주간의 퓨라린 투여가 ICR마우스의 혈중 지질 농도에 미치는 영향
표 퓨라린 섭취가 마우스의 혈중 AST와 ALT 수치에 미치는 영향
표 퓨라린 섭취가 ICR 마우스 대퇴부의 해면골 골밀도에 미치는 영향
표 퓨라린 섭취가 마우스의 대퇴부 BMD에 미치는 영향
표 퓨라린 섭위가 간 조직 내의 aromanase 및 SULT1E1의 발현에 미치는 영향
표 Experimental groups.
표 Radical scavenging activity of black garlic extracts.
표 The effect of BGE in mice injected with on paraquat-induced toxicity in vivo.
표 The effect of BGE on MDA concentrations in the plasma and the livers in mice injected with PQ.
표 The effect of BGE on the antioxidant enxyme activities and the plasma GSH levels in PQ induced mouse livers
표 A 2.8kb PCR product of putative mouse neurotrimin promoter region containing first exon and a little of intron obtained by PCR using specific primers selected from genomic sequence in silico(A) and constructed a vector containing a GFP/LacZ dual reporter driven by the promoter, designated pNtmGL(B). The integrity of the constructed vector was verified by identical enzyme digestion after cloning using restriction enzymes, XhoI and EcoRV(C) and demonstrated that simultaneous expressions of GFP and LacZ found in pNtmGL-transfected P19EC cells identically(D).
표 Coregulation of neurotrimin and a neuronal marker,
표 Blueberry extract and oral administration of the extract in the mouse
표 The body weight in control and experimental mice. Individual body weights were presented with different colors depending on the treatment(A).
표 The body weight in control and feeding mouse during feeding periods
표 RNA isolation from the brain and heart. RNAs from blueberry (Blue) and saline(Sal).
표 Dried cockroach corpses and droppings (a and b); they were hydrated to normal body water content and homogenized by a sonicator to prepare cockroach antigen soup (c); its appearance under microscope (d).
표 Preparation of mice with removed back patch hair (a and b).
표 Alterations in mean body weight of the NC/Nga mice during the experimental period.
표 Skin allergy-induced mice back-patch at 3 weeks of treatment.
표 Mean body weight (g) of the mice used during the entire experiment1
표 Alterations in some cytokine concentrations in the sera of the mice fed with Lact solution during 3 weeks of periods.
표 Alterations in some cytokine concentrations in the sera of the mice fed with Lact solution during 3 weeks of periods. ELISA assay was performed in three blind samples.
표 Comparisons in the relative levels of IFN-α, IFN-γ and TNF-α present in the sera of the mice fed with Saline or Lact by visualization of cytokine antigens (A).
표 Sca-1 expression in intestine (A) and skin tissues (B). Scale bars are 100μm.
표 Integrin-β5 expression in intestine (A) and skin tissues (B). Scale bars are 100μm.
표 Mast cell marker expression in intestine (A)and skin tissues (B). Scale bars are 100μ m.
표 The expressions and semi-quantitations of different cytokine transcripts in the kidney and spleen of the mice fed with saline or Lact for 3 weeks.
표 RT-PCR of upregulated and downregulated genes.
표 Expression intensity of up- and down regulated genes from 3 independent experiments.
표 PI를 통한 BBE의 세포 사멸 효과.
표 MCF7과 MCF10A 세포에서 BBE의 ROS 축적 효과.
표 RFP 형광유전자 발현 세포의 선발
표 뇌 미세교질 세포 감염반응에 관련된 분자들의 RNA수준에서의 BBE의 효과.
표 뇌 미세교질 세포의 감염반응과 ROS에 관련된 분자들의 단백질수준에서의 BBE의 효과.
표 감염반응 후 BV-2세포에서 iNOS, PrxI과 F4/80의 발현에 미치는 BBE의 효과.
표 ROS에 대한 BBE의 효과.
표 감염반응 후 BBE의 BV-2세포의 사멸에 미치는 영향.
표 세포분열에 대한 LPS와 BBE의 효과
표 BBE처리 후 DNA수준에서의 세포사멸 관찰.
표 산마늘 추출물의 조제 과정
표 MCF7-RFP mutant 세포를 이용한 realtime multiple in vitro assay.
표 MCF7-RFP mutant 세포와 MCF10A 세포의 혼합 배양 중 In Vitro Assay.
표 지방전구세포 3T3-L1 세포에 첨가한 산마늘 추출물의 효과.

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