초록

Ⅲ. 연구개발의 내용 및 범위
1) TRP 채널, 신경교세포 및 NMDA 수용체와 관련된 난치성 만성 감각이상(통증, 가려움증) 유발기전 및 제어기전 규명
2) 신규 진통표적물질의 도출과 진통후보물질 및 통증세포-특이적인 진통법 개발
3) 생체리듬과 수면에 관련된 새로운 유전자의 발굴 및 작용원리 규명
4) 신기능 단백질에 의한 신경세포 기능조절 기전 규명

Abstract ▼

Ⅲ. Contents and Extent
1) Study on the generating and control mechanisms of chronic pain and itch: TRP channels-, neuroglia- and NMDA receptor-related mechanisms
2) Digging out novel analgesic target molecules, and developing new analgesics or nociceptor-specific therapy
3) Digging out nove

Ⅲ. Contents and Extent
1) Study on the generating and control mechanisms of chronic pain and itch: TRP channels-, neuroglia- and NMDA receptor-related mechanisms
2) Digging out novel analgesic target molecules, and developing new analgesics or nociceptor-specific therapy
3) Digging out novel genes, involving biological rhythm and sleep, and their mechanisms
4) Study on the mechanisms of new proteins regulating neuronal functions