초록

Ⅳ. 연구개발결과
다른 외래 품종과 한우의 유전체 데이터를 이용한 비교 유전체 분석을 통하여, 한우만의 고유한 변이를 선별하였으며, 각종 도체 형질에 대하여 연관성 분석을 수행함으로써, 육질 및 질병 관련된 후보 변이를 발굴하였다. 또한, 한우 유전체 데이터를 이용한 추정 육종가의 정확도 분석 및 차세대 염기서열 분석을 통하여 한우 유전체 선발 통합 솔루션 파이프라인 구축하였다.

Abstract ▼

Along with humanity, cattle has been held an important place in the food problem. Studies for improving meat quality of the cattle have been actively processed. Recently, genomics has been rapidly developing because of improving biotechnology and information technology and applied to identify loci w

Along with humanity, cattle has been held an important place in the food problem. Studies for improving meat quality of the cattle have been actively processed. Recently, genomics has been rapidly developing because of improving biotechnology and information technology and applied to identify loci which are related with various phenotypes of cattle in world wise but not in Korea. For this reason, using next-generation sequencing and single nucleotide polymorphisms (SNPs) data of various cattle, we established genome database and the candidate loci about various phenotypes in Hanwoo breed.
In this study, the specific variants of Hanwoo breed were selected by comparison genome analysis with other breeds. By applying genetic association studies, the candidate SNPs for several carcass traits of Hanwoo breed were identified. In addition, we constructed the integrated solution pipeline for geneomic selection of Hanwoo breed.
The product from this study could accelerate the Hanwoo studies by providing Hanwoo genomic information to many researchers and become the cornerstone of omics studies of Hanwoo breed.