초록 ▼

● 광스위치를 사용하여 듀얼 포커스 영상 획득이 동시에 가능한 초고속, 초고해상도 Optical Coherence Tomography (OCT) 시스템 구현 (전안부 및 망막 동시 측정으로 안구 전체 이미징 가능)
● Open GL (Graphics Library)을 활용하여 2차원 및 3차원 영상 고속 디스플레이 알고리듬 개발
● GPU 신호처리를 이용한 안과용 3D 실시간 초고속 SD-OCT 소프트웨어/하드웨어 개발
● 2-D 소형 Mirror Scanner와 안저카메라 이용한 안과용 Handheld 이미지 프로

● 광스위치를 사용하여 듀얼 포커스 영상 획득이 동시에 가능한 초고속, 초고해상도 Optical Coherence Tomography (OCT) 시스템 구현 (전안부 및 망막 동시 측정으로 안구 전체 이미징 가능)
● Open GL (Graphics Library)을 활용하여 2차원 및 3차원 영상 고속 디스플레이 알고리듬 개발
● GPU 신호처리를 이용한 안과용 3D 실시간 초고속 SD-OCT 소프트웨어/하드웨어 개발
● 2-D 소형 Mirror Scanner와 안저카메라 이용한 안과용 Handheld 이미지 프로브를 개발하여 Primary Care Unit, Emergency Room, Point-Of-Care-Testing (POCT)에 활용될 수 있도록 함
● 녹내장 (Glaucoma), 노화 관련 황반 변성, 당뇨황반 부종, 망막출혈/허혈 진단용 전문가 진단 알고리듬 개발
● 망막에 노화와 관련된 Drusen, 당뇨병과 관련된 Hard Exudate (HE), Cyst 등이 존재할 때 발생하는 영상 Segmentation Error 최소화 알고리듬 개발
● 망막 Choroid, 산소포화도 등 기존 시스템의 기술적인 한계점으로 인하여 진단에 사용되지 못했던 새로운 안과 진단 영역 개척
● 임상실험을 통한 안과용 차세대 OCT 시스템 최적화 및 시제품 개발

Abstract ▼

Simultaneous dual-focus image acquisition system, GPU-based high-speed image processing software and hardware, image segmentation algorithms according to lesion, expert diagnostic algorithm, and multi-functional probes for ophthalmology diagnosis which are the final goals of this project are success

Simultaneous dual-focus image acquisition system, GPU-based high-speed image processing software and hardware, image segmentation algorithms according to lesion, expert diagnostic algorithm, and multi-functional probes for ophthalmology diagnosis which are the final goals of this project are successfully developed. The dual-focusing imaging acquisition system is the first OCT system in the world which can be obtained simultaneous eye anterior segment and retina images at high resolution using a single light source and a single spectrometer. We composed compact and low cost system by delivering signals from both imaging regions using a single spectrometer and an ultrafast 1x2 optical switch. This combines the GPU-based high-speed image processing software. As a result, real-time imaging is possible so we obtain 3D volume images of the whole eye. This project provides system development as well as optimized segmentation algorithm developed with accumulated database of Asian retina OCT images for 5 years. This algorithm was implemented to enable the segmentation of the representative diseases of the retina as well as not normal and, by extension, we developed diagnosis algorithm based the features of the disease by clinical analysis.Above techniques that have been developed in step1, in close cooperation research in step2, has been a single prototype. By developing a OCT system for retina diagnosis prior to prototype it is complete the clinical trial, thereby to supplement the securing database and segmentation algorithm. Also, upon receiving feedback on the improvement of the system and applied to the development of the final prototype. As a result, in addition to the retinal imaging via feedback through the accumulated technology and clinical trials for 5 years, add the user centric functions (fixation target, diopter adjustment, a variety of scan modes) to the actual commercialize of the Hand-held type of prototype so that it can be possible.
As a result, the completed development of medical equipment for the diagnosis of eye, which was developed with pure domestic technology, run the good faith research during five years of research execution, 33 Part of the domestic and international SCI (E) paper, we posted a non-SCI (E) paper of four at home and abroad. In addition, review national application 23, overseas applicants 13, National Register 19, and has achieved a review foreign registration 2, 3 of prototype development, 2 national technology transfer, it was to get the item permission 2.