초록

1. 실크 피브로인 생체막의 비염증성 만성 중이염 환자에 적용은 환자 치료에 적합함을 확인
2. 고식적 고막 재생술과 비교하여 치료성적의 통계학적 차이는 없음
3. 수술시간, 이루, 후유증발생 및 환자 만족도에서 실크 피브로인 생체막이 환자치료에 우월함을 확인
4. 본 연구의 결과에 따라 비염증성 만성 중이염 환자의 치료에 기존 방식의 대체치료방식으로 사용될 수 있음을 확인하였으며, 권장 치료방법으로 제안이 가능함을 확인

Abstract ▼

Objectives: Silk fibroin patching has been used to repair acute tympanic membrane perforations. Here, we describe the advantages and outcomes of this technique for chronic tympanic membrane perforations.

Study Design: Prospective randomized blind study

Materials and methods: Forty pati

Objectives: Silk fibroin patching has been used to repair acute tympanic membrane perforations. Here, we describe the advantages and outcomes of this technique for chronic tympanic membrane perforations.

Study Design: Prospective randomized blind study

Materials and methods: Forty patients were enrolled; half underwent cartilage myringoplasty, and the silk fibroin patch technique was applied in the remaining patients. We compared the closure, otorrhea, and complication rates; closure time; post-operative hearing gain; and patient satisfaction between the two groups.

Results: Demographic data (gender, site, age, duration, pre-operative air-bone gap, and perforation size and location) were not significantly different between the two groups. The closure rates and times, complication rates, and post-operative hearing gains were also similar in both groups. Although hearing gains were not significantly different, the degree of hearing gain was greater in the silk fibroin patch group. The mean operative time, otorrhea rate, and complication rate were also significantly better in the silk fibroin patch group. The intra-operative and immediate post-operative dizziness scores were higher in the conventional myringoplasty group.

Conclusion: Success rates were similar for the silk fibroin patch technique and conventional cartilage myringoplasty; however, patching was an easier, faster procedure. Our results suggest that the silk fibroin patch technique is a suitable treatment for chronic tympanic membrane perforation.