초록 ▼

본 연구과제는 1단계 연구(2009. 11월~2012. 10월)를 통하여 신규 자외선차단제 SID UV-CUT를 개발하였으며, 2단계 연구(2012. 11월~2015년. 10월)를 통하여 천연 식물추출물을 활용하여 광안정화, 광시너지 및 광보호 효과를 갖는 소재인 SIDP-Stabilizer series를 개발하였음. 신규 자외선차단제 SID UV-CUT은 유기-무기 복합소재인 폴리실세스퀴옥산 유도체로서 제조공정 확립, 생식발생독성시험, 기준 및 시험방법 확립을 통하여 식품의약품안전처에 자외선차단 기능성 고시 원료 등재를 진행하고

본 연구과제는 1단계 연구(2009. 11월~2012. 10월)를 통하여 신규 자외선차단제 SID UV-CUT를 개발하였으며, 2단계 연구(2012. 11월~2015년. 10월)를 통하여 천연 식물추출물을 활용하여 광안정화, 광시너지 및 광보호 효과를 갖는 소재인 SIDP-Stabilizer series를 개발하였음. 신규 자외선차단제 SID UV-CUT은 유기-무기 복합소재인 폴리실세스퀴옥산 유도체로서 제조공정 확립, 생식발생독성시험, 기준 및 시험방법 확립을 통하여 식품의약품안전처에 자외선차단 기능성 고시 원료 등재를 진행하고 있음. SID P-Stabilizer series는 170여종의 교목 잎추출물을 스크리닝하고 광안정화, 광시너지 및 광보호 효과와 관련된 다양한 유효성 평가를 진행함으로써, 최종적으로 SID P-Stabilizer C, -E, -A의 3종의 소재가 개발되었음. 연구과제의 주요성과는 학술논문 4건, 특허출원 3건, 특허등록 1건, 기타 학술발표 1건, ICID 소재 등록 3건과 SID UV-CUT이 적용된 제품 2건이 1단계에서 출시되었으며, SID P-Stabilizer C가 적용된 제품 9종이 2단계에서 출시되어 총 8.7억의 매출액이 발생하였음

Abstract ▼

I. The object and necessity of research and development
○ Sunscreen agents can be classified as ether organic of inorganic type. Both organic and inorganic UV screening agents have problems; inorganic powders often cause whitening and the organic agents may cause irritation and be absorbed throug

I. The object and necessity of research and development
○ Sunscreen agents can be classified as ether organic of inorganic type. Both organic and inorganic UV screening agents have problems; inorganic powders often cause whitening and the organic agents may cause irritation and be absorbed through skin
○ In addition, research of photostabilizers, light protective agent and booster has been actively conducted using natural plant extracts

Ⅱ. Content and range of research and development
○ Development and commercialization of new sunscreen agents
- Manufacturing process optimization of new sunscreen agents
- The reproductive & developmental toxicity tests of new sunscreen agents
- Notice listing of new sunscreen agents on MFDS
- Development of cosmetic products containing the new sunscreen agents
○ Development of materials containing photostabilization effect, boosting effect and photoprotection effect using the natural plant extracts
- Screening study of natural plant extracts
- Extraction, identification, purification and study of component agents
- In vitro assay of materials: photostabilization, boosting and photoprotection effect - Development of cosmetic products containing the new materials

Ⅲ. Results
○ Step 1 research was conducted the optimization of manufacturing precess, safety tests and notice listing of new sunscreen agents on MFDS for the development and commercialization of new sunscreen agents, SID UV-CUT
○ SID UV-CUT was to optimize the production process in pilot scale, and was available for mass production using outsourcing
○ We have evaluated the effect of SID UV-CUT on embryo-fetal development in SD rats and pre- and post-natal development and maternal function study by reproductive & developmental toxicity tests. The safety tests were carried out in GLP testing laboratory
○ Step 2 research was to develop the SID P-Stabilizer series by natural plant extracts. SID P-Stabilizer series contained the SID P-Stabilizer C, -A, -E
○ SID UV-CUT was applied to the Inhyeonjin Homme lotion, and SID P-Stabilizer C was applied to the Sarome Yyun-Mi brand

Ⅳ. Application of results
○ Application fields of SID UV-CUT will be used as major raw material for the sunscreen functional cosmetics, multi-functional cosmetics and general skin care cosmetics
○ SID P-Stabilizer Series is a material that can be applied to various skin care products as a photostabilizer, booster and photoprotection. In particular, it is expected to be consistently applied to products with anti-aging effects