Abstract ▼ AI-Helper

This experiment was designed to study for effects of pumpkin extract oil, calendula oil on wound healing as a natural product against canestin cream which is the composition wound healing cream. Standardized flank wounds were made on 32 mice divided into the following groups, control, pumpkin, calen...

This experiment was designed to study for effects of pumpkin extract oil, calendula oil on wound healing as a natural product against canestin cream which is the composition wound healing cream. Standardized flank wounds were made on 32 mice divided into the following groups, control, pumpkin, calendula, and canestin and it designed for 4 treatment for 10 days. The healing process was observed by macroscopic image, wound areas and biopcy of the open wound. The results were canestin and control groups have showed weight reduction cause by shock but pumpkin and calendula groups haven't showed weight reduction. .It returned to original weight in proportion healing wound. calendula's wound area started to change after 3 days of treatment and every group showed that area size increased except pumpkin group. Morphogically, only canestin group was healed before 10 days of treatment but it company with injury around healing tissue. According to biopcy, every group has inflammation response first 3days but 9 days calendula's regeneration has been cleaned and for the canestin group hasn't cleaned for epidermis. Conclusionally, canestin cream is fastest for healing but it concerned about inflammation and side effect after healing process. calendula oil is slower than canestin but it is avaliable to reduce for inflammation and side effect from shock.

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