Abstract Objective : The purpose of this research is to examine the effect of Bunsimgi-eum on the chest discomfort of Hwa-byung's major symptom and develope and establish pattern identification system in Hwa-byung. Method : In this randomized, double blinded, placebo-controlled study, we planned to ...
Abstract Objective : The purpose of this research is to examine the effect of Bunsimgi-eum on the chest discomfort of Hwa-byung's major symptom and develope and establish pattern identification system in Hwa-byung. Method : In this randomized, double blinded, placebo-controlled study, we planned to give Bunsimgi-eum or controlled medication for major symptoms of Hwa-byung. As preparatory research, advisor committee consisted of 15 neuropsychiatry professors of 11 Traditonal Korean Medical(TKM) colleges developed pattern identification instrument for Hwa-byung. Based on the review of the published literature, they agreed on five pattern identification, form, clinical index for each, and the mean weights to each symptom of five pattern identification. We focused on actualizing clinical dosage criteria by analyzing corelation between effect of Bunsimgi-eum and pattern identification. Randomized, double blinded, placebo-controlled study was set and patients diagnosed as Hwa-byung, were treated with Bunsimgi-eum or controlled medication. Score change for 100mm Visual Analogue Scale(VAS) for chest discomfort, Likert scale for major symptom of Hwa-byung, STAXI-K, STAI-K, BDI-K, WHOQOL-BREF and HRV were analyzed. Result : Hwa-byung pattern identification instrument was made in interviewer-rated form. By inputting clinical index, one out of five pattern identification - stagnation of liver Qi(肝氣鬱結), flare-up of the liver fire(肝火上炎), disharmony between heart and kidney(心腎不交), deficiency of both Qi and blood(氣血兩虛), malfunction of gallbladder due to phlegm stagnation(膽鬱痰擾) is determined. This development of pattern identification instrument contributed to establish basic frame of TCM diagnostic system in Hwa-byung. In regard of analysis of Hwa-byung clinical trial, 100mm Visual Analogue Scale(VAS) for chest discomfort was measured as the 1st evaluative instrument. Experimental group showed greater inclination for score change, but there were no significance. In all other valuation scales, there were significant difference within group, but there were no significant difference between groups . Conclusions : This research will provide evidence for TCM treatment on neuropsychiatric disorders. This objective methodology is expected to be applied to the subsequent researches. Development of items and structure of the pattern identification instrument of Hwa-byung will be evaluated as a good precedent for subsequent Hwa-byung researches. Key Words : Hwa-byung, Bunsimgi-eum(Fenxinqiyin), Clinical Trial, Randomized, Double Blinded, Placebo-controlled Study
Abstract Objective : The purpose of this research is to examine the effect of Bunsimgi-eum on the chest discomfort of Hwa-byung's major symptom and develope and establish pattern identification system in Hwa-byung. Method : In this randomized, double blinded, placebo-controlled study, we planned to give Bunsimgi-eum or controlled medication for major symptoms of Hwa-byung. As preparatory research, advisor committee consisted of 15 neuropsychiatry professors of 11 Traditonal Korean Medical(TKM) colleges developed pattern identification instrument for Hwa-byung. Based on the review of the published literature, they agreed on five pattern identification, form, clinical index for each, and the mean weights to each symptom of five pattern identification. We focused on actualizing clinical dosage criteria by analyzing corelation between effect of Bunsimgi-eum and pattern identification. Randomized, double blinded, placebo-controlled study was set and patients diagnosed as Hwa-byung, were treated with Bunsimgi-eum or controlled medication. Score change for 100mm Visual Analogue Scale(VAS) for chest discomfort, Likert scale for major symptom of Hwa-byung, STAXI-K, STAI-K, BDI-K, WHOQOL-BREF and HRV were analyzed. Result : Hwa-byung pattern identification instrument was made in interviewer-rated form. By inputting clinical index, one out of five pattern identification - stagnation of liver Qi(肝氣鬱結), flare-up of the liver fire(肝火上炎), disharmony between heart and kidney(心腎不交), deficiency of both Qi and blood(氣血兩虛), malfunction of gallbladder due to phlegm stagnation(膽鬱痰擾) is determined. This development of pattern identification instrument contributed to establish basic frame of TCM diagnostic system in Hwa-byung. In regard of analysis of Hwa-byung clinical trial, 100mm Visual Analogue Scale(VAS) for chest discomfort was measured as the 1st evaluative instrument. Experimental group showed greater inclination for score change, but there were no significance. In all other valuation scales, there were significant difference within group, but there were no significant difference between groups . Conclusions : This research will provide evidence for TCM treatment on neuropsychiatric disorders. This objective methodology is expected to be applied to the subsequent researches. Development of items and structure of the pattern identification instrument of Hwa-byung will be evaluated as a good precedent for subsequent Hwa-byung researches. Key Words : Hwa-byung, Bunsimgi-eum(Fenxinqiyin), Clinical Trial, Randomized, Double Blinded, Placebo-controlled Study
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