일개 화학 공장 근로자에 있어서 교대근무와 관상동맥 컴퓨터단층촬영 조영술을 통한 심혈관 질환의 연관성 Coronary artery atherosclerosis associated with shift work in chemical plant workers by using coronary computed tomography angiography원문보기
Objectives The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery computed tomography angiography (CCTA)...
Objectives The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery computed tomography angiography (CCTA).
Methods In this study, 110 male workers participated and underwent a CCTA examination for CAC scoring, which represents coronary artery plaque, and were evaluated for luminal stenosis. All of the subjects were working in the same chemical plant, of whom 70 worked day shifts and 40 worked rotating shifts.
Results In a multivariate logistic regression analysis, including age, smoking status, alcohol consumption, regular exercise, and waist circumference, shift work was associated with a 2.89-fold increase in the odds of developing coronary plaque compared with day work (odds ratio, 2.89; 95% confidence interval [CI], 1.07–7.82). The association between shift work and coronary plaque was strong after adjustment for age, low-density lipoprotein cholesterol, hypertension, and diabetes mellitus (odds ratio, 2.92; 95% CI, 1.02–8.33). In addition, the number of years of shift work employment was associated with coronary plaque. However, no association was found between shift work and coronary artery stenosis.
Conclusion Shift work could induce CAD onset via the atherosclerotic process, and shift work employment duration was associated with an increased risk of atherosclerosis in male workers.
Objectives The aim of this study was to investigate whether shift work is related to elevated risk of coronary artery disease (CAD) by determining the coronary artery calcium (CAC) score and the presence of coronary artery stenosis by using coronary artery computed tomography angiography (CCTA).
Methods In this study, 110 male workers participated and underwent a CCTA examination for CAC scoring, which represents coronary artery plaque, and were evaluated for luminal stenosis. All of the subjects were working in the same chemical plant, of whom 70 worked day shifts and 40 worked rotating shifts.
Results In a multivariate logistic regression analysis, including age, smoking status, alcohol consumption, regular exercise, and waist circumference, shift work was associated with a 2.89-fold increase in the odds of developing coronary plaque compared with day work (odds ratio, 2.89; 95% confidence interval [CI], 1.07–7.82). The association between shift work and coronary plaque was strong after adjustment for age, low-density lipoprotein cholesterol, hypertension, and diabetes mellitus (odds ratio, 2.92; 95% CI, 1.02–8.33). In addition, the number of years of shift work employment was associated with coronary plaque. However, no association was found between shift work and coronary artery stenosis.
Conclusion Shift work could induce CAD onset via the atherosclerotic process, and shift work employment duration was associated with an increased risk of atherosclerosis in male workers.
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