$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

The Effect of Aspalatone, a New Antithrombotic Agent, on the Specific Activity of Antioxidant Enzyme in the Rat Blood 원문보기

Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea, v.19 no.5, 1996년, pp.348 - 352  

Kim, Chin (Bukwang Pharmaceutical Ind., Co.) ,  Koo, Chang-Hui (Bukwang Pharmaceutical Ind., Co.) ,  Choi, Dong-Young (College of Pharmacy, Kangwon National University) ,  Cho, Yong-Joon (College of Pharmacy, Kangwon National University) ,  Choi, Jae-Ho (College of Pharmacy, Kangwon National University) ,  Im, Doo-Hyeon (College of Pharmacy, Kangwon National Univeristy) ,  Jhoo, Wang-Kee (College of Pharmacy, Kangwon National University) ,  Kim, Hyoung-Chun (College of Pharmacy, Kangwon national University)

Abstract AI-Helper 아이콘AI-Helper

The antioxidant efficacy of aspalatone, a new antithrombotic agent, has been recognized in the neurotoxic model and in the cardiotoxic model in proliminary studies. We examined the specific activity of antiosidnat enzyme in the rat blood following administrations of aspirin, maltol, aspirin together...

주제어

참고문헌 (24)

  1. H. Aebi 674 1974 Methods of Enzymatic Analysis Aebi, H., Catalase. In H.U. Bergmeyer (Eds.),Methods of Enzymatic Analysis, vol. 3, Academic Press, New York, pp. 674-684, 1974. 

  2. J. Neurochem. T.S. Brannan 35 1013 1980 10.1111/j.1471-4159.1980.tb07102.x Brannan, T.S., Marker, H.S., Weiss, C. and Kohen, G., Regional distribution of glutathione peroxidase in the adult rat brain.J. Neurochem., 35, 1013-1014 (1980). 

  3. Choi, J. H., Min, D. P., Han, S. H., Nam, S. W., Choi, D. Y., Kim, C., Koo, C. H., Jhoo, W. K. and Kim, H. C. Aspalatone as a scavenger of hydroxyl free radical.The 44th Convention of the Pharmaceutical Society of Korea, 183 (1995). 

  4. Method Enzymol. J. D. Crapo 53 382 1978 10.1016/S0076-6879(78)53044-9 Crapo, J. D., McCord, J. M. and Fridovich, I., Preparation and assay of superoxide dismutase.Method Enzymol., 53, 382-393 (1978). 

  5. Thromb. Res. J. P. Cruz De la 66 277 1992 10.1016/0049-3848(92)90278-I De la Cruz, J. P., Garcia, P. J. and de la Cuesta, F. S., Dipyridamole inhibits platelet aggregation induced by oxygen-derived free radicals.Thromb. Res., 66, 277-285 (1992). 

  6. Thromb. Res. M. Dikshit 70 317 1993 10.1016/0049-3848(93)90104-V Dikshit, M., Seth, P. and Srimal, R. C., Effect of molsidomine and free radical scavengers on the pulmonary thrombolism in mice.Thromb. Res., 70, 317-327 (1993). 

  7. Thromb. Res. C. Doutremepuich 76 225 1994 10.1016/0049-3848(94)90193-7 Doutremepuich, C., Aguejouf, O., Pintigny, Sertillanges, M. and Seze, O. D., Thrombogenic properties of ultra-low-dose of acetylsalicylic acid in a vessel model of laser-induced thrombus formation.Thromb. Res., 76, 225-229 (1994). 

  8. Ann. Intern. Med. M. R. Griffin 109 359 1988 10.7326/0003-4819-109-5-359 Griffin, M. R., Ray, W. A. and Sharffner, W., Nonsteroidal antiinflammatory drug use and death from peptic ulcer in elderly persons.Ann. Intern. Med., 109, 359-363 (1988). 

  9. Korean Biochem. J. B. H. Han 18 337 1985 Han, B. H., Park, M. H. and Han, Y. N., Studies on the antioxidant components of antioxidant componts of Korean ginseng (V): The mechanism of antioxidant activity of maltol and phenolic acid.Korean Biochem. J., 18, 337-340 (1985). 

  10. Arzneim.-Forsch/Drug Res. B. H. Han 44 1122 1994 Han, B. H., Suh, D. Y., Yang, H. O., Park, Y. H., Kang, Y. H. and Kim, Y. C., Synthesis and antiplatelet effect of the new antithrombotic agent aspalatone with low ulcerogenicity.Arzneim.-Forsch/Drug Res., 44, 1122-1126 (1994). 

  11. Thromb. Res. A. Jourdan 79 109 1995 10.1016/0049-3848(95)91519-Q Jourdan, A., Aguejouf, O., Imfault, P., Doutremepuich, F., Inamo, J. and Doutremepuich, C., Experimental thrombosis model induced by free radical. Application to aspirin and other different substances.Thromb. Res., 79, 109-123 (1995). 

  12. Thromb. Res. E. Kakishita 60 489 1990 10.1016/0049-3848(90)90233-3 Kakishita, E., Suehiro, A., Oura, Y. and Nagai, K., Inhibitory effect of vitamin E on spontaneous platelet aggregation in whole blood.Thromb. Res., 60, 489-499 (1990). 

  13. Thromb. Res. A. Kawabata 72 321 1993 10.1016/0049-3848(93)90141-A Kawabata, A. and Hata, T., Possible involvement of oxygen-derived free radicals in abnormal hemostasis induced by start stress (repeated cold stress) in laboratory animals.Thromb. Res., 72, 321-331 (1993). 

  14. Kim, C., Koo, C. H., Nam, S. W., Choi, D. Y., Choi, J. H., Suh, J. H., Im, D. H., Jhoo, W. K. and Kim, H. C., Proconvulsant action of aspirin and anticonvulsant action of aspalatone in the kainic acid model; Involvement of antioxidant mechanism of aspalatone.The 44th Convention of the Pharmaceutical Society of Korea, 180 (1995a). 

  15. Kim, C., Koo, C. H., Nam, S. W., Choi, D. Y., Choi, J. H., Jhoo, W. K. and Kim, H. C., Aspalatone, maltol and vitamin E protected, but not aspirin, doxorubicin-induced toxicity: Aspalatone as an antioxidant.The 44th Convention of the Pharmaceutical Society of Korea, 182 (1995b). 

  16. Arch. Pharm. Res. H. C. Kim 13 121 1990 10.1007/BF02857787 Kim, H. C., Jhoo, W. K., Kim, J. T., Lee, S. T. and Hur, I. H., Protective effect of copper against pancreatic insult on streptozotocin-induced diabetogenic rat.Arch. Pharm. Res., 13, 121-125 (1990). 

  17. Thromb. Res. R. Kumari 69 101 1993 10.1016/0049-3848(93)90007-B Kumari, R., Dikshit, M. and Scrimal, R. C., Free radical scavenging mechanism during pulmonary thromboembolism in rats.Thromb. Res., 69, 101-111 (1993). 

  18. Thromb. Res. A. Muruganandam 67 385 1992 10.1016/0049-3848(92)90268-F Muruganandam, A., Drouillard, C., Thibert, R. J., Draisey, T. F. and Mutus, B., Glutathione metabolic enzyme activities in diabetic platelets as a function of glycemic control.Thromb. Res., 67, 385-397 (1992). 

  19. Thromb. Res. D. D. Prinpe 62 365 1991 10.1016/0049-3848(91)90010-T Prinpe, D. D., Menichelli, A., Matteis, W. D., Giulio, S. D., Giordani, M. and Agro, A. F., Hydrogen peroxide is an intermediate in the platelet activation cascade triggered by collagen, but not by thrombin.Thromb. Res., 62, 365-375 (1991). 

  20. Koryo Insam Hakhoechi J. G. Shin 14 187 1990 Shin, J. G., Park J. W., Pyo, J. K., Kim, M. S. and Chung, M. H., Protective effect of a ginseng component, maltol (2-methyl-3-hydroxy-4-pyrone) against tissue damage induced by oxygen radicals.Koryo Insam Hakhoechi, 14, 187-190 (1990). 

  21. Biochem. Biophys. Res. Com. P. M. Sinet 67 910 1975 10.1016/0006-291X(75)90763-9 Sinet, P. M., Michelson, A. M. and Jerome, H., Increase in glutathione peroxidase activity in erythrocyte from trisomy 21 subjects.Biochem. Biophys. Res. Com., 67, 910-915 (1975). 

  22. Thromb. Res. J. J. Sixma 67 305 1992 10.1016/0049-3848(92)90005-U Sixma, J. J. and Groot, P. G. D., The ideal antithrombotic drug.Thromb. Res., 67, 305-311 (1992). 

  23. Thromb. Res. H. G. Spanos 72 175 1993 10.1016/0049-3848(93)90184-P Spanos, H. G., Aspirin fails to inhibit platelet aggregation in sheep.Thromb. Res., 72, 175-182 (1993). 

  24. Arch. Pharm. Res. D. Y. Suh 19 112 1996 10.1007/BF02976844 Suh, D. Y., Han, Y. N. and Han, B. H., Maltol, an antioxidant component of Korean red ginseng, shows little prooxidant activity.Arch. Pharm. Res., 19, 112-115 (1996). 

저자의 다른 논문 :

관련 콘텐츠

오픈액세스(OA) 유형

FREE

Free Access. 출판사/학술단체 등이 허락한 무료 공개 사이트를 통해 자유로운 이용이 가능한 논문

섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로