$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

Abstract

Bacillary is the most common form of H. pylori observed during human infection. However, it is known that the morphology change of H. pylori from bacillary to coccoid can be occurred with a response to the environmental stresses such as the nutrient depletion, accumulation of toxic metabolites, pH alteration, and exposure to antimicrobial agents. The coccoid form of H. pylori, which is viable but non-culturable in vitro, seems to be the major cause of antibiotic resistancy and high reinfectability of H. pylori. In this regard, we studied the environmental factors that can induce the morphological change in vitro of H. pylori, and the change of fatty acid composition of plasma membrane. The morphological change from bacillary to coccoid could be observed with the depletion of nutrients, pH variation and reactive oxygen species added in the culture media. This morphologic conversion was paralleled by a dramatic decrease in unsaturated fatty acids and an increase in saturated fattv acids of plasma membrane. The change in composition of membrane fatty acid seems to be a kind of protection mechanism of H. pylori against these environmental stresses.

저자의 다른 논문

참고문헌 (37)

  1. Unidentified curved bacilli on gastric epithelium in active chronic gastritis , Warren, J. R.;B. Marshall , Lancet / v.ⅰ,pp.1273-1275, 1983
  2. Hyphotesis on the pathogenesis and natural histoy of Helicobacter pylori-induced inflammation , Martin J. Blaser , Gastroenterology / v.102,pp.720-727, 1992
  3. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation , Martin J. Blaser , J. Infect. Dis. / v.161,pp.626-633, 1990
  4. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation , Martin J. Blaser , Gastroenterology / v.93,pp.371-383, 1990
  5. Relation of Campylobacter pyloridis to gastritis and peptic ulcer , Buck, G. E.;K. A. Parshall;C. P. Davis , J. Infect. Dis. / v.153,pp.664-669, 1986
  6. Campylobacter-like organisms in chronic gastritis, peptic ulcer and gastric carcinoma , Jiang, S. J.;M. K. Chan , Scand. J. Gastroenterol. / v.22,pp.553-558, 1987
  7. Changes in Helicobacter pylori ultrastructure and antigens during conversion from the bacillary to the coccoid form , Mohammed, B.;B. Philippe;Q. Nathalie , Infect. Immun. / v.64,pp.2331-2335, 1996
  8. Characterization of the morphologic conversion of Helicobacter pylori from bacillary to coccoid forms , Catrenich, C. E.;K. M. Makin , Scand. J. Gastroentrol. / v.26,pp.58-64, 1991
  9. Coccoid forms of Helicobacter pylori in the human stomach , Chan, W. Y.;P. K. Hui;K. M. Leung;C. John;C. S. Ng. , Am. J. Clin. Pathol. / v.102,pp.503-507, 1994
  10. Helicobacter pylori: a fickle germ , Cellini, L.;N. Allocati , Microbiol. Immunol. / v.38,pp.25-30, 1994
  11. Morphological transformation of Helicobacter pylori during prolonged incubation: Association with decreased acid resistance , Moshkowitz, M.;A. Gorea;N. Arber;F Konikoff;S. Berger;T. Gilat , J. Clin. Pathol. / v.47,pp.172-174, 1994
  12. Survival of Helicobacter phlori in water and saline , West, A. P.;M. R. Millar , J. Clin. Patho. / v.43,pp.609, 1990
  13. The genesis of coccal form of Helicobacter pylori , Jones, A. P.;A. Currey;Malfertheiner P.(ed.);Dischuneit H.(ed.) , Helicobacter pylori, gastritis and peptic ulcer / v.,pp.29-37, 1990
  14. Biology of disease: Free radicals and tissue injury , Bruce A. Freeman;James D. Crapo , Laboratory Investigation / v.47,pp.412-426, 1982
  15. The coccoid forms Helicobacter pylori. Criteria for their viability , Bode, G.;F. Mauch;P. Malertheiner , Epidemiol. Infect. / v.111,pp.483-490, 1993
  16. Immunological activities of Helicobacter pylori porins , Turfano, M. A.;F. Rossno , Infect. Immun. / v.62,pp.1392-1399, 1994
  17. Helicobacter pylori increases proliferation of gastric epithelial cells , Fan, X. G. , Gut. / v.38,pp.19-22, 1996
  18. The role of acid inhibition in the treatment of Helicobacter pylori infection , Axon, A.T.R. , Scand. J. Gastroenterol. / v.29,pp.16-23, 1994
  19. Coccoid Helicobacter pylori not in vitro reverts in mice , Cellini, L.;N. Allocati;D. Angelucci;T. Lezzi;E. D. Campil , Microbiol. Immunol. / v.38,pp.843-850, 1994
  20. Morphologic conversion of Helicobacter pylori from bacillary to coccoid form , Sorberg, M.;M. Nilsson;H. Hanberger , Eur. J. Microbiol. Infect. Dis. / v.15,pp.216-219, 1996
  21. Dimorphism of Campylobacter pylori , Mai, U.;G. Geis;H. Leying;F. Megraud(ed.);H. Lamouliatte(ed.) , Gastroducdenal pathology and Campylobacter pylori / v.,pp.29-33, 1989
  22. Survival of Helicobacter pylori in the environment (Abstract Ⅰ 101) , Shamat, M.;M. Mai , Annu. Meet. Am. Soc. Microbiol / v.,pp., 1990
  23. Electron microscopy of the coccoid form of Campylobacter jejuni , Buck, G. E.;K. A. Parshall;C.P. Davis , J. Clin. Microbiol. / v.18,pp.420-421, 1983
  24. A comparative study of the rod and coccoid forms if Campylobacter jejuni ATCC 29428 , Moran, A. P.;M. E. Upton , J. Appl. Bacteriol. / v.60,pp.103-110, 1986
  25. Christie, W. W. , Lipid analysis(2nd edition) / v.,pp.1-6, 1990
  26. The effects of unsaturated fatty acids on Helicobacter pylori invitro , Khulusi, S.;H. A. Ahmed;P. Patel;M. A. Mendel;T. C. Northfield , J. Med. Microbiol. / v.42,pp.276-282, 1995
  27. Fatty acid composition of Bifidobacterium and Lactobacillus strains , Veerkamp, J. H. , J. Bacteriol. / v.108,pp.860-867, 1971
  28. Factors affectiong growth and antibiotic susceptibility of Helicobacter pylori: effect of pH and urea on the survival of a wild-type strain and a urease-deficient mutant , Sjostrom, J. E.;H. Larsson , J. Med. Microbiol. / v.44,pp.425-433, 1996
  29. Microbiological aspects of Helicobacter pylori , Goodwin, C. S.;J. A. Armstrong , Eur. J. Clin. Microbiol. Infect. Dis. / v.9,pp.1-13, 1990
  30. The bacteria behind ulcers , Martin J. Blaser , Scientific American / v.,pp.104-107, 1996
  31. Helicobacter pylori and gastric acid: Biological and therapeutic implication , Catherine C. Mcgowan;Timothy L. Cover;Martin J. Blaser , Gastroenterology / v.110,pp.926-938, 1996
  32. Does omeprazole improve antimicrobial therapy directed towards gastric Campylobacter pylori in patients with antral gastritis? , Unge, P.;A. Gad , Scand. j. Gastroenterol. / v.24,pp.49-54, 1989
  33. Omeparazole, Helicobacterpylori, gastritis and duodenal ulcer , Biasco, G.;M. Migholi , Lancet. / v.1,pp.1403, 1989
  34. Interaction of Helicobacter pylori and its fatty acids parietal cells and gastric $H^+/k^+$-ATPase , Beil, W.;C. Birkholz;S. Wagner , Gut. / v.35,pp.1176-1180, 1994
  35. Review article: Oxygen toxicity, oxygen radicals, transition metals and disease , Barry, H.;M. C. John , Biochem. J. / v.219,pp.1-14, 1984
  36. Redox cycling of iron and lipid peroxidation , Minito, G.;S. D. Aust. , Lipid. / v.27,pp.219-226, 1993
  37. A simple flurometric assay for lipid-peroxide in blood plasma , Yagi, K. , Biochem. Med. / v.15,pp.212-216, 1976

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음

원문보기

원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일