A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-...
A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-salicylamido-2-hydroxypropyl-amino derivatives were prepared. Several of these compounds were screened for antiinflammatory, analgesic, antipyretic and ulcerogenic activities.
A new series of pyridazine, pyrazoles, pyrazolidine-3,5-dione, Semicarbazide, thiosemicarbazides, hydantoin, thiohydantoins, 1,2,4-triazoles, S-triazolo[3,4-b]-1,3,4-thiadiazoles incorporated indirectly into salicylamide moiety at position 2 were synthesized. Also the synthesis of novel series of 3-salicylamido-2-hydroxypropyl-amino derivatives were prepared. Several of these compounds were screened for antiinflammatory, analgesic, antipyretic and ulcerogenic activities.
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제안 방법
, 1982). Based on these findings the purpose of the present work is to synthesize a variety of some new heterocycles, namely pyridazine, pyrazoles, pyrazolidinedione, triazole, S-tri-azok)[3, 4-b]-1, 3, 4-thiadiazdes, imidazolidin-4, 5-diones and other related structure incorporated indirectly into the salicylamide moiety at its position 2 hoping that the res니Itant compounds might exhibit a promising antiinflammatory and analgesic activities.
데이터처리
Statistical analysis of the data was comp니ted via the st니dent's t-test. A 0.
후속연구
During the biological evahjation, the animals tolerated the tested compounds quit well and no mortalities have been recorded among them such preliminary results enco니rage further studies.
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