화재에 의한 독성가스의 노출은 인간에게 있어서 화재시 생명에 아주 위험한 요소일 것이다. 다양한 화재에 의한 독성가스의 노출 중 본 논문에서는 경기도 안산시 재개발지구에서 한 연립주택을 이용하여 실재화재와 같은 조건으로 화재 시험을 하였다. 화재시 발생하는 가스 CO, $CO_2$, $O_2$, $SO_2$, NO 및 $NO_2$등을 측정하였으며, 발생하는 가스를 실험동물인 백서(S.D.)에 노출시켜 2분 간격으로 혈액을 체취 하였다. 독성 평가를 위하여 백서의 혈액과 혈청 중 Glucose, AST(GOT), ALT(GPT), CBC Count 및 CO(carboxy)-Hb를 분석하였다. 폭로되는 CO의 농도와 백서의 혈액중 CO-Hb 농도사이에 양-반응 관계(dose-response relationship)를 보였다.
화재에 의한 독성가스의 노출은 인간에게 있어서 화재시 생명에 아주 위험한 요소일 것이다. 다양한 화재에 의한 독성가스의 노출 중 본 논문에서는 경기도 안산시 재개발지구에서 한 연립주택을 이용하여 실재화재와 같은 조건으로 화재 시험을 하였다. 화재시 발생하는 가스 CO, $CO_2$, $O_2$, $SO_2$, NO 및 $NO_2$등을 측정하였으며, 발생하는 가스를 실험동물인 백서(S.D.)에 노출시켜 2분 간격으로 혈액을 체취 하였다. 독성 평가를 위하여 백서의 혈액과 혈청 중 Glucose, AST(GOT), ALT(GPT), CBC Count 및 CO(carboxy)-Hb를 분석하였다. 폭로되는 CO의 농도와 백서의 혈액중 CO-Hb 농도사이에 양-반응 관계(dose-response relationship)를 보였다.
It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confront-ing people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which ...
It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confront-ing people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which include CO, $CO_2$, $O_2$, $SO_2$, NO and $NO_2$, were measured by a gas analyzer. A group of lab rats were exposed to the toxic gases released from fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST(GOT), ALT(GPT), CBC Count and CO(carboxy)-Hb in the blood samples. Shown from the analysis is the does-response relationship between the CO concentration that rats were exposed to and the CO-Hb concentration in rat blood.
It has long been recognized that exposure to fire-induced toxic gases is a fatal hazard confront-ing people in fires. In this study, an indoor fire experiment was conducted in an unoccupied residential building located in An-san city, Kyoung-gi province, and the composition of effluent gases, which include CO, $CO_2$, $O_2$, $SO_2$, NO and $NO_2$, were measured by a gas analyzer. A group of lab rats were exposed to the toxic gases released from fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST(GOT), ALT(GPT), CBC Count and CO(carboxy)-Hb in the blood samples. Shown from the analysis is the does-response relationship between the CO concentration that rats were exposed to and the CO-Hb concentration in rat blood.
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가설 설정
2. The gases inducted to chamber 1 had greater influence on the glucose concentrations in serum of rats than those in chamber 2. Also, glucose concentrations increased sharply after 10 minutes elapsed.
3. Chamber 1 had greater influence on the concentration of CO-Hb in blood than chamber 2 did. 4 minutes after the steep rise of CO concentration in test chamber; a rise of CO-Hb concentrations in rat blood appeared resultingly This shows the dose-response relationship between CO concentration and CO-Hb concentration.
제안 방법
Carbon monoxide (CO), released in a large amount from wood and other carbon fires, is specially one of the fetal toxic gases. In this study an indoor fire experiment was conducted in an unoccupied residential building located in An-san city Ifyoung-ji province, and the composition of effluent gases, which include CO, CQ, 02, SO2, NO and NC2, were measured by a gas analyzer A group of lab rats (Sprague dawley) were exposed to the toxic gases released from the fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST (GOT), ALT(GPT), CBC Count and CO(carboxy)- Hb in blood samples.
In this study an indoor fire experiment was conducted in an unoccupied residential building located in An-san city Ifyoung-ji province, and the composition of effluent gases, which include CO, CQ, 02, SO2, NO and NC2, were measured by a gas analyzer A group of lab rats (Sprague dawley) were exposed to the toxic gases released from the fire, and the blood samples of the rats were gathered every 2 minutes. A toxicity evaluation was conducted by analyzing the concentrations of Glucose, AST (GOT), ALT(GPT), CBC Count and CO(carboxy)- Hb in blood samples.
대상 데이터
1 shows the abandoned residential building, where the experiment of exposing rats to the fire-induced gases was performed. The lab rats used in the experiment are Sprague Dawley (age 7 weeks, male, 215 ± 15 g). The rats were exposed to the gases in two chambers(l m x 1.
The lab rats used in the experiment are Sprague Dawley (age 7 weeks, male, 215 ± 15 g). The rats were exposed to the gases in two chambers(l m x 1.2 m x 1.5 m), which were connected to the residential building by an induction pipe (Fig. 2). The pipes were suspended in the living room(4 m x 7 m x 3 m) and child room (3 m x 5 m x 3 m) at a height of 1.
참고문헌 (5)
Kim, I. S., 'Study of Toxic Gases From Flame Interior Materials of Pleasure Place', Graduate School of Environmental, Hanyang University,(1998)
Yi, K. N. and Kwon, O. H., 'Clinical Pathology File', Third Edition, Eui-Hak Publishing(2000)
Curtis D. Klaassen, Mary O. Amdur and John Doull, 'Casarett and doull's Toxicaity- the Basic Science of Poisons', Macmillan Publishing Company, Third Edition, pp.801-824(1986)
T. Morikawa and Yanai, T Nishina, 'Toxicaity Evaluation of Fire Effluent Gases from Experimental Fires in a Building', Journal of Fire Sciences, Vol.5, pp248-271(1987)
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