$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"

과학기술 지식인프라 ScienceON

상세검색 다국어 입력
도움말도움말
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

MyON담기
내보내기

Comparing the Performance of One-column Process and Four-zone Simulated Moving Bed by Computer Simulation

Biotechnology and bioprocess engineering v.9 no.5 , 2004년, pp.362 - 368  
Kim Young Sik (Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University ) ;  Lee Chong Ho ( Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University ) ;  Wankat Phillip C. ( School of Chemical Engineering, Purdue University ) ;  Koon Yoon Mo ( Department of Biological Engineering, ERC for Advanced Bioseparation Technology, Inha University)
Abstract

A new one-column chromatography process, analogous to a four-zone simulated moving bed (SMB), was presented. The basic principle of the process was identical to that of a four-zone SMB. The process consisted of one chromatographic column and four tanks, instead of the four columns in the four-zone SMB (1-1-1-1), and has been used for the separation of two amino acids, phenylalanine and tryptophan, using an ion exchange resin. The operating parameters for the one-column process and four-zone SMB were obtained from equilibrium theory. Computer simulations were used to compare the performances of the new one column process to that of the general four-zone SMB, using Aspen $Chromatography^{TM}$ v 11.1. The differences between the one-column and SMB processes in terms of the purities and yields of phenylalanine and tryptophan were less than 4 and about $6\%$, respectively. The lower purities of the one-column process were due to the loss of the developed concentration profiles in the column when the liquid was stored in tanks. The one-column process gave great flexibility, and would be useful for reconstructing an existing conventional chromatography process to one of a SMB.

주제어

#Simulated moving bed   #one-column process   #computer simulation   #amino acid  

참고문헌 (19)

  1. Broughton, D. B., R. W. Neuzil, J. M. Pharis, and C. S. Brearley (1970) Parex process for recovering paraxylene. Chem. Eng. Prog. 66: 70-82 
  2. Ludemann-Homburger, O., R. M. Nicoud, and M. Bailly (2000) VARICOL process: A new multicolumn continuous chromatographic process. Sep. Sci. Technol. 35: 1829-1862 
  3. Ma, Z. and N.-H. L. Wang (1997) Standing wave analysis of SMB chromatography: Linear systems. AICHE J. 43: 2488-2508 
  4. Zang, Y. and P. C. Wankat (2002) 5MB operation strategy-partial feed. Ind. Eng. Chem. Res. 41: 2504-2511 
  5. Storti, G., M. Mazzotti, M. Morbidelli, and S. Carra (2000) Robust design of binary counter-current adsorption separation processes. AICHE J. 46: 1384-1399 
  6. Xie, Y, D. Wu, Z. Ma, and N.-H. L. Wang (2000) Extended standng wave design method for simulated moving bed chromatography: linear systems. Ind. Eng. Chem. Res. 39: 1993-2005 
  7. Rodrigues, A. E., J. M. Loureiro, and L. S. Pais (1997) Separation of 1,1' -bi-2-naphthol enantiomers by continuous chromatography in simulated moving bed. Chem. Eng. Sci. 52: 25-35 
  8. Yang, Y. J., S. H. Hwang, S. M. Lee, Y. J. Kim, and Y. M. Koo (2002) Continuous cultivation of lactobacillus rhamnosus with cell recycling using an acoustic cell settler. Biotechnol. Bioprocess Eng. 7: 357-361 
  9. Row, K. H., C. H. Lee, and J. H. Kang (2002) Parameter estimation of perillyl alcohol in RP-HPLC by moment analysis. Biotechnol. Bioprocess Eng. 7: 11-16 
  10. Wankat, P. C. (1994) Moving Bed and Sirnulated Moving Bed Sorption Separation: Rate-controlled Separations. Glasgow, London, UK 
  11. Houwing, J., S. H. van Hateren, H. A. S. Billiet, and L. A. M. van der Wielen (2002) Effect of salt gradients on the separation of dilute mixtures of proteins by ion-exchange in simulated moving beds. J. Chrornatogr. A. 952: 85-98 
  12. Wu, D., Y. Xie, Z. Ma, and N.-H. L. Wang (1998) Design of SMB chromatography for amino acid separations. Ind. Eng. Chem. Res. 37: 4023-4035 
  13. Ma, Z. and N.-H. L. Wang (1998) Anine-Zone simulating moving bed for the recovery of glucose and xylose from biomass hydrolyzate. Ind. Eng. Chem. Res. 37: 3699-3709 
  14. Migliorini, C., M. Wendlinger, M. Mazzotti, and M. Morbidelli (2001) Temperature gradient operation of a simulated moving bed unit. Ind. Eng. Chem. Res. 40: 2606-2617 
  15. Ching, C. B., K. H. Chu, K. Hidajat, and D. M. Ruthven (1993) Experimental study of a simulated counter-current adsorption system: VII. Effects of non-linear and interacting isotherms. Chem. Eng. Sci. 48: 1343-1445 
  16. Ching, C. B., K. H. Chu, K. Hidajat, and M. S. Uddin (1992) Comparative study of flow schemes for a simulated countercurrent adsorption separation process. AIChE J. 38: 1744-1750 
  17. Navarro, A., H. Caruel, L. Rigal, and P. Phemius (1997) Continuous chromatographic separation process: Simulated moving bed allowing simultaneous withdrawal of three fractions. Sep. Purif Technol. 20: 39-50 
  18. Broughton, D. B. (1968) Molex case history of a process. Chem. Eng. Prog. 64: 60-72 
  19. Mazzotti, M., G. Storti, and M. Morbidelli (1997) Operation of simulated moving bed units for nonlinear chromatographic separations. J. Chrornatogr. A. 769: 3-24 

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음

원문보기

원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일