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NTIS 바로가기약학회지 = Yakhak hoeji, v.49 no.3, 2005년, pp.205 - 211
이상규 (시카고 대학교 의학과)
The 3' UTR (3' untranslated region) plays important roles in controlling gene expression through regulating 3' polyadenylation, mRNA export, subcellular localization, translational efficiency, and mRNA stability. Changes in the 3' UTR sequence in an expressed transcript can result in functional chan...
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Sonenberg, N. : mRNA translation: influence of the 5' and 3' untranslated regions. Curr. Opin. Genet. Dev. 4, 310 (1994)
Decker, C. J. and Parker, R. : Diversity of cytoplasmic functions for the 3' untranslated region of eukaryotic transcripts. Curr. Opin. Cell Biol. 7, 386 (1995)
Wickens, M., Anderson, P. and Jackson, R. J. : Life and death in the cytoplasm: messages from the 3' end. Curr. Opin. Genet. Dev. 7, 220 (1997)
Gallie, D. R. : A tale of two termini: a functional interaction between the termini of an mRNA is a prerequisite for efficient translation initiation. Gene. 216, 1 (1998)
Varani, G. : Delivering messages from the 3' end. Proc. Natl. Acad Sci. USA 98, 4288 (2001)
Groenen, P. J., Wansink, D. G., Coerwinkel, M., van den Broek, W., Jansen, G. and Wieringa, B. : Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct properties. Hum. Mol. Genet. 9, 605 (2000)
Davis, B. M., McCurrach, M. E., Taneja, K. L., Singer, R. H. and Housman, D. E. : Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts. Proc. Natl. Acad. Sci. USA 94, 7388 (1997)
Rimokh, R., Berger, F., Bastard, C., Klein, B., French, M., Archimbaud, E., Rouault, J. P., Santa Lucia, B., Duret, L., Vuillaume, M. and et al. : Rearrangement of CCND1 (BCL1/PRAD1) 3' untranslated region in mantle-cell lymphomas and t(11q13)-associated leukemias. Blood. 83, 3689 (1994)
Russell, J. E. and Liebhaber, S. A. : The stability of human beta-globin mRNA is dependent on structural determinants positioned within its 3' untranslated region. Blood. 87, 5314 (1996)
Conne, B., Stutz, A. and Vassalli, J. D. : The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology? Nat. Med. 6, 637 (2000)
Velculescu, V. E., Zhang, L., Vogelstein, B. and Kinzler, K. W. : Serial analysis of gene expression. Science 270, 484 (1995)
Zhou, G., Chen, J., Lee, S., Clark, T., Rowley, J. D. and Wang, S. M. : The pattern of gene expression in human CD34(+) stem/progenitor cells. Proc. Natl. Acad Sci. USA 98, 13966 (2001)
Lee, S., Zhou, G., Clark, T., Chen, J., Rowley, J. D. and Wang, S. M. : The pattern of gene expression in human CD15+ myeloid progenitor cells. Proc. Natl. Acad Sci. USA 98, 3340 (2001)
Schuler, G. D., Boguski, M. S., Stewart, E. A., Stein, L. D., Gyapay, G., Rice, K, White, R. E., Rodriguez-Tome, P., Aggarwal, A., Bajorek, E., Bentolila, S., Birren, B. B., Butler, A., Castle, A. B., Chiannilkulchai, N., Chu, A., Clee, C., Cowles, S., Day, P. J., Dibling, T., Drouot, N., Dunham, I., Duprat, S., East, C., Hudson, T. J. and et al. : A gene map of the human genome. Science 274, 540 (1996)
Siomi, M. C., Siomi, H., Sauer, W. H., Srinivasan, S., Nussbaum, R. L. and Dreyfuss, G. : FXRl, an autosomal homolog of the fragile X mental retardation gene. EMBO J. 14, 2401 (1995)
Inoue, S. B., Siomi, M. C. and Siomi, H. : Molecular mechanisms of fragile X syndrome. J. Med. Invest. 47, 101 (2000)
Ralph, S. J., Thomas, M. L., Morton, C. C. and Trowbridge, I. S. : Structural variants of human T200 glycoprotein (leukocytecommon antigen). EMBO J. 6, 1251 (1987)
Trowbridge, I. S. : CD45. A prototype for transmembrane protein tyrosine phosphatases. J. Biol. Chem. 266, 23517 (1991)
Lynch, K W. and Weiss, A. : A model system for activationinduced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Mol. Cell Biol. 20, 70 (2000)
Goodall, G. J., Dominguez, F. and Horecker, B. L. : Molecular cloning of cDNA for human prothymosin alpha. Proc. Natl. Acad Sci. USA 83, 8926 (1986)
Driessen, C., Bryant, R. A., Lennon-Dumenil, A. M., Villadangos, J. A., Bryant, P. W., Shi, G. P., Chapman, H. A. and Ploegh, H. L. : Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells. J. Cell Biol. 147, 775 (1999)
Shi, G. P., Villadangos, J. A., Dranoff, G., Small, C., Gu, L., Haley, K. J., Riese, R., Ploegh, H. L. and Chapman, H. A. : Cathepsin S required for normal MHC class II peptide loading and germinal center development. Immunity 10, 197 (1999)
Peng, S. S., Chen, C. Y. and Shyu, A. B. : Functional characterization of a non-AUUUA AU-rich element from the cjun proto-oncogene mRNA: evidence for a novel class of AUrich elements. Mol. Cell Biol. 16, 1490 (1996)
Zaidi, S. H. and Malter, J. S. : Amyloid precursor protein mRNA stability is controlled by a 29-base element in the 3'-untranslated region. J. Biol. Chem. 269, 24007 (1994)
Zaidi, S. H. and Malter, J. S. : Nucleolin and heterogeneous nuclear ribonucleoprotein C proteins specifically interact with the 3'-untranslated region of amyloid protein precursor mRNA. J. Biol. Chem. 270, 17292 (1995)
Tanguay, R. L. and Gallie, D. R. : Translational efficiency is regulated by the length of the 3' untranslated region. Mol. Cell Biol. 16, 146 (1996)
Lopez, A. J. : Alternative splicing of pre-mRNA: developmental consequences and mechanisms of regulation. Annu. Rev. Genet. 32, 279 (1998)
Smith, C. W. and Valcarcel, J. : Alternative pre-mRNA splicing: the logic of combinatorial control. Trends Biochem. Sci. 25, 381 (2000)
Mironov, A. A., Fickett, J. W. and Gelfand, M. S. : Frequent alternative splicing of human genes. Genome Res. 9, 1288 (1999)
Brett, D., Hanke, J., Lehmann, G., Haase, S., Delbruck, S., Krueger, S., Reich, J. and Bork, P. : EST comparison indicates 38% of human mRNAs contain possible alternative splice forms. FEBS Lett. 474, 83 (2000)
Beaudoing, E., Freier, S., Wyatt, J. R, Claverie, J. M. and Gautheret, D. : Patterns of variant polyadenylation signal usage in human genes. Genome Res. 10, 1001 (2000)
Mignone, F., Gissi, C., Liuni, S. and Pesole, G. : Untranslated regions of mRNAs. Genome Biol. 3, REVIEWS0004 (2002)
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