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논문 상세정보

자외선 B 조사 hairless 마우스에서 일광화상세포 발생 억제에 대한 녹차의 효과

The effect of green tea on ultraviolet B-induced sunburn cell production in the skin of hairless mouse

Abstract

In this study we assessed the influences of ultraviolet (UV) light B radiation on epidermal cells by apoptotic sunburn cell (SBC) and the effect of green tea treatment on the inhibition of SBC formation in SKH1-hr mouse. The extent of changes following $200mJ/cm^2$ (0.5 mW/sec) was studied at 0, 3, 6, 12, 18, 24, 30 or 36 hours after exposure. SBCs were recognized by 3 hours after irradiation. There was tendency to increase from 3 hours to 24 hours and decrease from then to 36 hours after irradiation. The mice that received 0, 25, 50, 100, 200, 400 or $800mJ/cm^2$ of UVB were examined 24 hours after irradiation. The SBCs were induced as the radiation dose increases from 0 to $200mJ/cm^2$. A further increase of radiation dose has little further effect. The frequency of UVB ($200mJ/cm^2$)-induced SBC formation was reduced by intraperitoneal injection of green tea extract (p<0.01).

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이 논문을 인용한 문헌 (1)

  1. Lee, Hyun-Hwa ; Song, Seon-Young 2010. "A Study of Effectiveness of Lithospermum erythrorhizon Extracts on the Skin by UVB-Irradiation C57BL/6 Mouse" 한국현미경학회지 = Korean journal of microscopy, 40(3): 139~145 

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