$\require{mediawiki-texvc}$
  • 검색어에 아래의 연산자를 사용하시면 더 정확한 검색결과를 얻을 수 있습니다.
  • 검색연산자
검색연산자 기능 검색시 예
() 우선순위가 가장 높은 연산자 예1) (나노 (기계 | machine))
공백 두 개의 검색어(식)을 모두 포함하고 있는 문서 검색 예1) (나노 기계)
예2) 나노 장영실
| 두 개의 검색어(식) 중 하나 이상 포함하고 있는 문서 검색 예1) (줄기세포 | 면역)
예2) 줄기세포 | 장영실
! NOT 이후에 있는 검색어가 포함된 문서는 제외 예1) (황금 !백금)
예2) !image
* 검색어의 *란에 0개 이상의 임의의 문자가 포함된 문서 검색 예) semi*
"" 따옴표 내의 구문과 완전히 일치하는 문서만 검색 예) "Transform and Quantization"
쳇봇 이모티콘
안녕하세요!
ScienceON 챗봇입니다.
궁금한 것은 저에게 물어봐주세요.

논문 상세정보

고혈압 환자에 도움을 줄 수 있는 한방 다류 개발

Development of Functional Tea Products for Hypertension Patients with the Mixed Medicinal Herbal Extracts

초록

본 연구는 두충을 주 원료로 고안된 한방 혼합 다류가 고혈압 질환자의 혈압, 혈청지질 및 혈액학적 변화에 미치는 영향을 평가하기 위하여 수행하였다. 한방 혼합 다류를 시험 4주간 복용한 그룹과 시험 전 그룹을 비교한 결과, 수축기 혈압은 167.14 mmHg에서 134.86 mmHg로, 이완기 혈압은 100.00 mmHg에서 87.10 mmHg로 뚜렷하게 저하되었다. 혈청지질 중 총콜레스테롤(TC), 고밀도-콜레스테롤(HDL-C), 저밀도-콜레스테롤(LDL-C)의 농도 및 동맥경화지수(AI)는 유의적인 차이가 없었다. 반면, 한방 혼합 다류를 복용 시 중성지방(TG) 농도가 237.10 mg/dL에서 145.00 mg/dL로 강하게 감소되었다. 시험 4주 후와 시험개시 전의 혈액학적 지표(적혈구, 백혈구, 헤마토크리트, 헤모글로빈, 혈소판 및 호모시스테인)를 비교한 경우, 유의적 변화는 관찰되지 않는 반면 평균 적혈구 혈색소 농도(MCHC)는 유의적으로 2.70% 증가되었다. 이상의 결과로 부터 두충을 주 원료로 고안된 한방 혼합 다류는 중성지방 농도를 감소시킴으로써 혈압을 저하시키는 것으로 추정하며, 평균 적혈 수혈 색소 농도를 증가시킴을 확인하였다.

Abstract

This study was carried out to investigate the effects of Eucommia ulmoides Oliver (Du-Zhong) as a main ingredient in a mixture of various medicinal herbal extracts on blood pressure, serum lipid concentrations, and hematological variables in hypertensive patients. After 4 weeks on drinking the mixed medicinal herbal teas, systolic blood pressure remarkably decreased from 167.14 to 134.86 mmHg and diastolic blood pressure decreased from 100.00 to 87.10 mmHg. In terms of serum lipid profiles, there were no differences in total-cholesterol, HDL-cholesterol, LDL-cholesterol level, and atherogenic index, However, the level of triglycerol was significantly reduced from 237.1 before the experiment to 145.00 mg/dL after 4 weeks on drinking the mixed medicinal herbal teas. Serum triglyceride were remarkably reduced from 237.1 to 145.00 mg/dL in the hypertensive patients who had taken the combined medicinal herbal extracts. Compared with data obtained from the patients before the experiment, there were no differences in hematological variables (RBC, WBC, hematocrit, hemoglobin, platlets and homocysteine) after the 4 weeks experiments, but mean corpuscular hemoglobin concentration was significantly increased by 2.70% (p<0.05) in the blood samples. Based on these findings, it can be presumed that the examined mixed medicinal herbal tea may be effective in lowering blood pressure and in increasing mean corpuscular hemoglobin concentration due to reduced serum triglyceride levels in hypertension patients.

저자의 다른 논문

참고문헌 (28)

  1. Choi HI, Lee SI, Ahn DK, Kim HC (1997) A study on the antihypertensive effect of Epimedii herba. J Hebology 12: 35-44. 
  2. Choi HJ, Zhang YB, An BJ, Choi C (2002) Identification of biologically active compounds from Panax ginseng C.A. Meyer extracts. Korean J Food Sci 34: 493-497. 
  3. Hwang JB, Yang MO, Shin HK (1997) Survey for approximate composition and mineral content of medicinal herbs. Korean J Food Sci Technol 29: 671-679. 
  4. Hwang WI (1992) A study on the growth inhibition of human colon cancer by Eucommia leaf extract. Korean J Food Nutr 5: 13-21. 
  5. Hong HD, Shim EJ, Kim KI, Choi SY, Han CK (2007) Effect of Gastrodiae elata Blume components on systolic blood pressure and serum lipid concentration in spontaneously. J Korean Soc Food Sci Nutr 36: 174-179. 
  6. Kim HY (2000) Hypocholesterolemic and hypotensive activities of Eucommina ulmoides Oliver. Food Industry Nutr 5: 27-28. 
  7. Nakazawa Y, Odagiri N, Imai R, Yoshii T, Tagashira E, Nakata C, Nakamura T, Asaumi M, Onizuka S, Yahara S, Nohara T (1997) Effect of Eucommia leaf (Eucommia ulmoides Oliver leaf; Du-Zhong yge) extract on blood pressure (I). J Nat Med 51: 392-398. 
  8. Lee SE, Bang JG, Seong NS (2004) Inhibitory activity on angiotensin converting enzyme and antioxidant activity of Hovenia dubs Thumb. Cortex extract. Korean J Medicinal Corp Sci 12: 79-84. 
  9. Oh HS, Kim HC, Lee SI, Ahn DK (1995) Effects of Eucommiae Cortex and folium on the ovariectomized rat as the model of postmenopaual osteoporosis. J Herbology 10: 59-68. 
  10. Hong ND, Rho YS, Kim JW, Won DH, Kim NJ, Cho BS (1988) Studies on the general pharmacological activities of Eucommia ulmoices Oliver. Kor J Pharmaconn 19: 102-110. 
  11. Jang HJ, Ra DY, Kim OC, Park JY (1990) Volatile components of Du-Chung barks. J Korean Agric Chem Soc 33: 116-119. 
  12. Lee SE, Seong NS, Bang JG, Kang SW, Lee SU, Jeong TY (2003) Inhibitory effect against angiotensin-converting enzyme and antioxidant activity of Panax ginseng C.A. Meyer extracts. Korean J Medicinal Corp Sci 11: 236-245. 
  13. Nakamura T, Nakazawa Y, Onizuka S, Satoh S, Chiba A, Sckihashi K, Miura A, Yasugahara N, Sasaki Y (1997) Antimutagenicity of Tochu tea: 1. The clastogen-suppressing effect of Tochu tea in CHO cells and mice. Mutation Res 388: 7-20. 
  14. Lim SH, Baik IK, Lee HS, Kee YJ, Chung NS, JHlo SY, Kim SS (1995) Effects of the life style in patients with coronary artery disease on the serum lipid concentrations and atherosclerotic coronary lesion. Korean J Lipidology 5: 71-83. 
  15. Ahn SW, Kim YG, Kim MH, Lee HY, Seong NS (1999) Comparison of biological activities on Rehmannia radix and R. radix Preparata produced in Korea. Korean J Medicinal Corp Sci 7: 257-262. 
  16. Whang WK, Choi SB, Kim IH (1996) Physiological activities of mixed extracts of Acantopanics senticosi Radicis Cortex and Eucommiae Cortex. Kor J Pharmacogn 27: 64-75. 
  17. Hong ND, Rho YS, Won DH, Kim NJ, Cho BS (1986) Studies on the anti-diabetic activity of Eucommia ulmoides Oliver. The Abstracts of 17th Annual Convention of the Korean Society of Pharmacognosy. pp 87. 
  18. Lee IK, Kim JG (2000) Effects of extract of Eucommia ulmoides Oliver on the reduction of lead and cadmium in organs of rats. J Korean Public Health Assoc 26: 22-28. 
  19. Lee YC, Synn HA, Lee KY, Park YH, Lee CS (1992) A study on concentrations of serum lipids and food & daily habit of healthy Korean adults. Korean J Lipidology 2: 41-51. 
  20. Kim NJ (1995) Pharmacological activity of Eucommia ulmoides. Kor J Pharmacogen 26: 192-198. 
  21. Sasaki Y, Satoh S, Chiba A, Murakami M, Sekihashi K, Tanaka M, Moribayashi N, Kudou C, Ham Y, Nakazawa Y, Nakamura T, Onizuka 0 (1996) Antimutagenicity of Tochu tea: 2. Suppressing effect of Tochu tea. Mutation Res 387: 203-214. 
  22. Cushman DW, Cheung HS (1971) Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung. Biochem Pharmacol 20: 1637-1648. 
  23. Choe SI, Lee YM, Heo Tl (2003) Screening of hyaluronidase inhibitory and free radical scavenging activity in vitro of traditional herbal medicine extracts. Korean J Biotechnol Bioeng 18: 282-288. 
  24. Kim HC (2006) In the pharmacology of oriental internal medicine. Jimmundang press, Seoul, Korea, pp 364-447. 
  25. Metori K, Furutsu M, Takahashi S (1997) The prevention effect of ginseng with Du-Zhong leaf extract on plasma and protein metabolism in aging. Biol Pharm Bull 20: 237-242. 
  26. Chung MH, Park CW (1975) Influence of Eucommial Cortex of Korea on blood pressure response of rabbits. Kor J Pharmacog 6: 39-42. 
  27. Kim JH, Whang SG (1997) Effects of mugwort, dried orange peel and Duchung on lipid metabolism in hyperlipidemia rats. Kor J Nutr 30: 895-903. 
  28. Baek NI, Ahn EM, Hahn JT, Lee DW, Sohn HO, Kwon BM (1999) Isolation of monoamine oxidase B inhibitory compound from the leaves of Eucommia ulmoides Oliver. J Korean Soc Agric Chem Biotechnol 42: 166-198. 

이 논문을 인용한 문헌 (0)

  1. 이 논문을 인용한 문헌 없음

원문보기

원문 PDF 다운로드

  • ScienceON :

원문 URL 링크

원문 PDF 파일 및 링크정보가 존재하지 않을 경우 KISTI DDS 시스템에서 제공하는 원문복사서비스를 사용할 수 있습니다. (원문복사서비스 안내 바로 가기)

상세조회 0건 원문조회 0건

DOI 인용 스타일