[논문]네일샵 종사자들의 공기 중 화학물질에 대한 직업적인 노출과 생물학적인 모니터링

양지희; 한돈희

네일샵 종사자들의 공기 중 화학물질에 대한 직업적인 노출과 생물학적인 모니터링
Occupational Exposure of Nail Technicians to Airborne Chemicals and Biological Monitoring 원문보기

한국산업위생학회지 = Journal of Korean Society of Occupational and environmental hygiene, v.20 no.1, 2010년, pp.53 - 62

양지희 (을지대학교 피부건강관리과) , 한돈희 (인제대학교 보건안전공학과)

초록
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일샵 종사자들의 1) 공기 중 화학물질에 대한 노출정도를 파악하고 2) 공기 중 미량으로 존재하는 아세톤 및 톨루엔과 요 중 아세톤 및 마뇨산과의 연관성을 분석하여 후자들이 아직도 생물학적인 지표로 유용한지를 알아보고자 본 연구를 실시하였다. 경인 지역소재 9개의 네일숍에 근무하는 20명의 종사자들을 노출군으로 선정하였으며 이 작업과 무관한 일반 여성 20명을 대조군 선정하였다. 작업장 공기는 한 네일숍에 3개씩 총 27개의 시료를 가능한 한 작업자의 호흡영역에서 가장 가까운 곳에서 지역시료로 채취하였다. 공기 중 유기증기 13개 물질, 포름알데히드, 요 중 아세톤, 요 중 마뇨산을 가스크로마토그래프, 자외선분광광도계 그리고 GC/MS를 이용하여 분석하였다. 유기증기 13개 물질 중 아세톤과 톨루엔은 모든 네일샵에서 검출되었다. 각 네일샵 공기 중 유기증기의 노출정도를 기하평균(GM)과 복합물질간 상가작용을 이용하여 평가를 하였을 때 노동부 노출기준의 10%, ACGIH의 13% 수준에 불과하여 네일샵 종사자들의 유기증기에 대한 직업적인 노출정도는 매우 낮은 것으로 판단되었다. 요 중 아세톤과 마뇨산은 공기 중 아세톤과 툴루엔과 약한 상관성을 보였다(아세톤의 상관 계수 r=0.49, 톨루엔의 상관계수 r=0.45). 그러나 요 중 아세톤의 농도가 노출군과 대조군 간에 통계적으로 유의하지 않았으며 마뇨산은 대조군에 비해 노출군에서 약간 높은 것으로 나타났다. 따라서 저자들은 공기 중 아세톤과 톨루엔의 농도가 낮은 작업장에서 요 중 아세톤과 마뇨산을 생물학적 지표로 삼는 것은 적절하지 못한 것으로 결론지었다.

주제어

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제안 방법

All data obtained were subjected to statistical analyses with the Statistical Analysis System (SAS Institute, Inc., North Carolina, USA) computer program, including simple descriptive analysis and correlation analysis between technicians (exposed group) and control group.

대상 데이터

A total number of 13 airborne solvents were measured in the study, but each concentration of solvent was far below both Korean OELs and ACGIH TLVs. When evaluated with the addictive effects using GM value of each solvent, overall airborne solvents exposed were no more than 10% of Korean OELs, 13% of ACGIH TLVs.
As Table 1 shown, a total number of 9 salons were selected in Seoul (7 salons) and Incheon (2 salons) in which most of nail salons were located in Korea. No attempt was made to select a random sample.
Two to twelve nail technicians work at each salon. The floor area of salons surveyed in this study ranged in size from 20.1 m2 to 165.6 m2. Seven salons were single room with a general room ventilator attached by a propeller fan and two salons were open spaces in mart which did not need a ventilator.
No attempt was made to select a random sample. Two to twelve nail technicians work at each salon. The floor area of salons surveyed in this study ranged in size from 20.

이론/모형

The method for determining urinary creatinine was derived from a previously reported method (Clark and Thompson, 1949) and was used to correct the urinary metabolite concentration for urinary dilution by expressing the results as the amount of metabolite excreted per gram of creatinine. For urinary acetone 2 mL of urine was mixed with 5 μL of internal standard (1,2-dichloroethane), and analyzed by the same system which was used to determine hippuric acid.

성능/효과

Another study suggested that urinary hippuric acid should be no longer considered the method of choice for the biological monitoring of exposure to toluene because of the large interindividual variation in the background level (L?f et al, 1993). In this study, very weak correlation (r: 0.45) between airborne toluene and urinary hippuric acid excretion was found. As Table 6 shown, the excretion of hippuric acid for exposed group was only slightly above the background level for control group, even if significant difference was found, which was similar to the result of the previous study (Tardif et al, 1998).
45 ppm. The reason that GSDs of cyclohexanone, o-Xylene, MIBK and TCE ranged from 1.04 to 1.80, being relatively low, was due to the small number of samples detected. If the contaminants were detected in as many as samples of the other contaminants, the variations of those would be very wide spectrum as those of the others.
90. This study revealed that correlation between acetone exposure level and urinary acetone was found even if very weak (r: 0.49). Weak correlation may be caused by limited number of samples (N: 20).

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저자의 다른 논문 :

표제어: PCR

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