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NTIS 바로가기소아감염 = Korean journal of pediatric infectious diseases, v.19 no.2, 2012년, pp.43 - 54
Group B streptococcus (GBS) is the leading cause of neonatal sepsis and meningitis in developed countries. This article reviews the neonatal invasive GBS disease, maternal GBS colonization, and prevention strategies in the context of recent epidemiological changes in Korea. Although Korean neonates ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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B군 사슬알균은 신생아와 임산부에게 어떤 영향을 미치는가? | B군 사슬알균(Group B Streptococcus, GBS)은 생식기나 하부소화관에 무증상으로 집락화(asymptomatic colonization)될 수 있으나, 신생아와 3개월 미만의 영아에서 패혈증과 수막염의 주요 원인균이며 임신부에서 융모양막염, 산욕기 패혈증, 요로 감염, 그리고 제왕절개 수술이나 회음절개술 후의 상처 감염을 일으킬 수 있다1) . 또한 임신 후반기에 생식기와 직장에 중증 집락형성(heavy colonization)된 경우 신생아의 조발형 GBS 감염(earlyonset disease)의 빈도가 증가한다고 알려져 있다2, 3) . 어린 영아와 임신부 외에도 노인, 면역저하자, 혹은 기저질환이 있는 성인에서 침습성 세균 감염의 원인균이 된다2). | |
신생아에서 GBS 감염은 어떻게 분류되는가? | 신생아에서 GBS 감염은 생후 6일 이내에 발병하는 조발형(early-onset disease)과 생후 7-90일 사이에 발병하는 지발형(late-onset disease)으로 나뉜다(Table 1) 2) . 조발형은 대개 출생 직후 혹은 24시간 내에 발병하며 경과가 급속히 진행하는 것이 특징이고 주로 폐렴이나 패혈증으로 나타난다. | |
GBS 감염 중 조발형의 특징은 무엇인가? | 신생아에서 GBS 감염은 생후 6일 이내에 발병하는 조발형(early-onset disease)과 생후 7-90일 사이에 발병하는 지발형(late-onset disease)으로 나뉜다(Table 1) 2) . 조발형은 대개 출생 직후 혹은 24시간 내에 발병하며 경과가 급속히 진행하는 것이 특징이고 주로 폐렴이나 패혈증으로 나타난다. 조발형 질환에서 치명률은 미국의 경우 1970년대에 50%였으나 근래에는 4-9% 정도로 보고되고 있다9-11) . |
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