[논문]Prevalence and Correlation of Oral Lesions among Tobacco Smokers, Tobacco Chewers, Areca Nut and Alcohol Users

Sujatha, D.; Hebbar, Pragati B.; Pai, Anuradha

doi:10.7314/apjcp.2012.13.4.1633

Prevalence and Correlation of Oral Lesions among Tobacco Smokers, Tobacco Chewers, Areca Nut and Alcohol Users 원문보기

Asian Pacific journal of cancer prevention : APJCP, v.13 no.4, 2012년, pp.1633 - 1637

Sujatha, D. (Department of Oral Medicine and Radiology, The Oxford Dental College and Hospital) , Hebbar, Pragati B. (Department of Oral Medicine and Radiology, The Oxford Dental College and Hospital) , Pai, Anuradha (Department of Oral Medicine and Radiology, The Oxford Dental College and Hospital)

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Introduction: The incidence of oral premalignant and malignant lesions is on the rise due to an increased number of people taking in tobacco and alcohol related habits. Material and Methods: 1028 patients with tobacco, alcohol and areca nut habits attending our Department of Oral Medicine and Radiology formed the study sample. An interviewer based questionnaire was used to record the habit details. All the patients were then examined clinically for the presence of lesions. Chi square and Fisher exact tests were used to assess the statistical significance of the study parameters. Results: Males had a higher prevalence and comprised 87.9% of the sample. The commonest habit in this study sample was smoking (39.2%) followed by smokeless tobacco use (28.1%). Out of the 1028 patients with habits 40% had no clinically detectable changes in their mucosa. Of the mucosal changes leukoplakia (14%) was the commonest. Conclusions: This study provided information about the habit trends in the patients visiting this institution. The study may serve as a useful tool in educating the patients about the deleterious effects of oral tobacco, alcohol and betel exposure.

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제안 방법

Along with patient’s demographic details, information regarding the type of habit, duration, frequency, site of placement, period of contact with the mucosa and history of discontinuation of habit were recorded using the standardized interviewer based questionnaire.
The limitations of this study include potential information bias as self reporting by the patient was used to collect the information hence underreporting of habits could have taken place. Another possible flaw could be detection bias as the researcher was aware of the habit history of the patient prior to oral examination. In future research the examiner can be blinded to the habit details and should examine the oral cavity first to prevent such bias.
Establishing doseresponse relationships is important because such information provides evidence to educate users about the deleterious effects of such habits and to reduce the quantity or completely stop such habits. The purpose of the present study was to know the prevalence of tobacco, areca nut, betel quid and alcohol associated lesions only among patients with these habits and to correlate the dose response relationship of oral habits with potentially malignant oral lesions among this subset of the population.

성능/효과

Of the 226 patients with a combination of two habits only 31% (n=70) had no detectable changes and the commonest lesions in the decreasing order of frequency were leukoplakia 17.7%, leukedema 12.4%, smoker’s melanosis 10.2%, OSMF at 8.8% and 6.2% cases of smoker’s palate and tobacco induced keratosis.
Of the remaining patients leukoplakia was the highest 14% (n=144), followed by smoker’s melanosis 11.8% (n=121) and OSMF 8.2% (n=84).

후속연구

Further studies including comparisons of demographic data as well as dose response relationship with oral lesions with larger sample size and in the general population need to be performed. Studies observing the effects of cessation of oral habits are sparse (Martin et al.

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Prevalence and Correlation of Oral Lesions among Tobacco Smokers, Tobacco Chewers, Areca Nut and Alcohol Users 원문보기

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Prevalence and Correlation of Oral Lesions among Tobacco Smokers, Tobacco Chewers, Areca Nut and Alcohol Users 원문보기

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