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Nontuberculous Mycobacterial Lung Disease Caused by Mycobacterium terrae in a Patient with Bronchiectasis 원문보기

Tuberculosis and respiratory diseases : TRD = 결핵 및 호흡기 질환, v.72 no.2, 2012년, pp.173 - 176  

Koh, Won-Jung (Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ,  Choi, Go-Eun (Department of Microbiology and Research Institute for Medical Sciences, Infection Signaling Network Research Center, Chungnam National University College of Medicine) ,  Lee, Nam-Yong (Department of Laboratory Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine) ,  Shin, Sung-Jae (Department of Microbiology and Research Institute for Medical Sciences, Infection Signaling Network Research Center, Chungnam National University College of Medicine)

Abstract AI-Helper 아이콘AI-Helper

We report a rare case of lung disease caused by Mycobacterium terrae in a previously healthy woman. A 45-year-old woman was referred to our hospital due to a chronic cough with sputum. A computed tomography scan of the chest revealed bronchiolitis in conjuction with bronchiectasis in both lungs. Non...

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제안 방법

  • The patient was treated with oral clarithromycin (1,000 mg/day), rifampin (600 mg/day), and ethambutol (800 mg/day) for 18 months. The treatment outcome was favorable; the patient's symptoms resolved completely, radiographic findings improved (Figure 1B), and negative conversion of sputum cultures was achieved and maintained after 12 months of antibiotic therapy (Figure 1B).

대상 데이터

  • 32 U/mL, normal range, 0∼37 U/mL). Her height was 161 cm and body weight was 51 kg. A human immunodeficiency virus (HIV) antibody test was negative.
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참고문헌 (17)

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  2. Smith DS, Lindholm-Levy P, Huitt GA, Heifets LB, Cook JL. Mycobacterium terrae: case reports, literature review, and in vitro antibiotic susceptibility testing. Clin Infect Dis 2000;30:444-53. 

  3. Chen HW, Lai CC, Tan CK. Arthritis caused by Mycobacterium terrae in a patient with rheumatoid arthritis. Int J Infect Dis 2009;13:e145-7. 

  4. Telenti A, Marchesi F, Balz M, Bally F, Bottger EC, Bodmer T. Rapid identification of mycobacteria to the species level by polymerase chain reaction and restriction enzyme analysis. J Clin Microbiol 1993;31: 75-8. 

  5. Lee H, Park HJ, Cho SN, Bai GH, Kim SJ. Species identification of mycobacteria by PCR-restriction fragment length polymorphism of the rpoB gene. J Clin Microbiol 2000;38:2966-71. 

  6. Alban SM, Sella SR, Miranda RN, Mira MT, Soccol VT. PCR-restriction fragment length polymorphism analysis as a tool for Mycobacterium species identification in lepromas for lepromin production. Lepr Rev 2009;80: 29-42. 

  7. Clinical and Laboratory Standards Institute (CLSI). Susceptibility testing of mycobacteria, nocardiae, and other aerobic actinomycetes; approved standard. Document no, M24-A. Wayne, PA: CLSI; 2003. 

  8. Wayne LG, Sramek HA. Agents of newly recognized or infrequently encountered mycobacterial diseases. Clin Microbiol Rev 1992;5:1-25. 

  9. Koh WJ, Kwon OJ, Jeon K, Kim TS, Lee KS, Park YK, et al. Clinical significance of nontuberculous mycobacteria isolated from respiratory specimens in Korea. Chest 2006;129:341-8. 

  10. Kuze F, Mitsuoka A, Chiba W, Shimizu Y, Ito M, Teramatsu T, et al. Chronic pulmonary infection caused by Mycobacterium terrae complex: a resected case. Am Rev Respir Dis 1983;128:561-5. 

  11. Krisher KK, Kallay MC, Nolte FS. Primary pulmonary infection caused by Mycobacterium terrae complex. Diagn Microbiol Infect Dis 1988;11:171-5. 

  12. Tonner JA, Hammond MD. Pulmonary disease caused by Mycobacterium terrae complex. South Med J 1989; 2:1279-82. 

  13. Lee CK, Gi HM, Cho Y, Kim YK, Lee KN, Song KJ, et al. The genomic heterogeneity among Mycobacterium terrae complex displayed by sequencing of 16S rRNA and hsp 65 genes. Microbiol Immunol 2004;48:83-90. 

  14. Koh WJ, Lee KS, Kwon OJ, Jeong YJ, Kwak SH, Kim TS. Bilateral bronchiectasis and bronchiolitis at thinection CT: diagnostic implications in nontuberculous mycobacterial pulmonary infection. Radiology 2005; 35:282-8. 

  15. Jeon K, Kwon OJ, Lee NY, Kim BJ, Kook YH, Lee SH, et al. Antibiotic treatment of Mycobacterium abscessus lung disease: a retrospective analysis of 65 patients. Am J Respir Crit Care Med 2009;180:896-902. 

  16. Koh WJ, Jeon K, Lee NY, Kim BJ, Kook YH, Lee SH, et al. Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus. Am J Respir Crit Care Med 2011;183:405-10. 

  17. Kim RD, Greenberg DE, Ehrmantraut ME, Guide SV, Ding L, Shea Y, et al. Pulmonary nontuberculous mycobacterial disease: prospective study of a distinct preexisting syndrome. Am J Respir Crit Care Med 2008; 78:1066-74. 

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