[논문]Fetal Loss Rate after Mid-trimester Amniocentesis

Han, You-Jung; Kim, Yun-Young; Lee, Si-Won; Kim, Min-Hyoung; Chung, Jin-Hoon; Ahn, Hyun-Kyong; Han, Jung-Yeol; Kim, Moon-Young; Yang, Jae-Hyug; Choi, Kyu-Hong; Park, So-Yeon; Ryu, Hyun-Mee

doi:10.5734/jgm.2012.9.1.22

Fetal Loss Rate after Mid-trimester Amniocentesis 원문보기

Journal of genetic medicine, v.9 no.1, 2012년, pp.22 - 24

Han, You-Jung (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Kim, Yun-Young (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Lee, Si-Won (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Kim, Min-Hyoung (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Chung, Jin-Hoon (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Ahn, Hyun-Kyong (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Han, Jung-Yeol (Department of Obstetrics and Gynecology, Cheil General Hospital and Women's Healthcare Center, Kwandong University College of Medicine) , Kim, Moon-Young (Department of Obstetrics and Gynecology,) , Yang, Jae-Hyug , Choi, Kyu-Hong , Park, So-Yeon , Ryu, Hyun-Mee

Abstract ▼ AI-Helper

Purpose: The aim of this study was to asses the fetal loss rate after mid-trimester amniocentesis. Materials and Methods: This was a retrospective cohort study including singleton pregnant women who underwent mid-trimester amniocentesis at Cheil General Hospital from January 2008 through December 2010. The procedure-related fetal loss was defined as miscarriage within 2 weeks after amniocentesis. We evaluated the fetal loss rate within 2 weeks after amniocentesis and fetal loss rate before 24 gestational weeks. Results: During the study period, a total of 4,356 singleton pregnant women underwent mid-trimester amniocentesis. A total of Five hundred ninety six women were excluded owing to follow up loss and termination of pregnancy due to abnormal karyotype or major anomaly. At our institute, the fetal loss rate within 2 weeks was 0.1% and before 24 gestational weeks was 0.3% after amniocentesis. Conclusion: The fetal loss rate after mid-trimester amniocentesis in our study is lower than previously reported rate. We suggest that amniocentesis is a safe procedure.

주제어

AI 본문요약
AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

문제 정의

The aim of this study was to asses the fetal loss rate after mid-trimester amniocentesis at our institution.

제안 방법

Pregnancy outcomes were classified as fetal loss within 2 weeks or 2-4 weeks after amniocentesis, before 24 gestational weeks, intrauterine fetal death more than 24 gestational weeks, and live born. The procedure-related fetal loss was defined as miscarriage within 2 weeks after amniocentesis and these cases were analyzed.

대상 데이터

We excluded 596 women who were lost to follow up or terminated their pregnancy due to abnormal karyotype or major anomaly. Finally a total of 3,760 patients were included in this study.

성능/효과

Pregnancy outcomes were classified as fetal loss within 2 weeks or 2-4 weeks after amniocentesis, before 24 gestational weeks, intrauterine fetal death more than 24 gestational weeks, and live born. The procedure-related fetal loss was defined as miscarriage within 2 weeks after amniocentesis and these cases were analyzed.

참고문헌 (10)

Nanal R, Kyle P, Soothill PW. A classification of pregnancy losses after invasive prenatal diagnostic procedures: an approach to allow comparison of units with a different case mix. Prenat Diagn 2003;23:488-92.

상세보기
American College of Obstetricians and Gynecologists. ACOG Practice Bulletin No. 88, December 2007. Invasive prenatal testing for aneuploidy. Obstet Gynecol 2007;110:1459-67.

상세보기
Mazza V, Pati M, Bertucci E, Re C, Ranzi A, Percesepe A, et al. Age-specific risk of fetal loss post second trimester amniocentesis: analysis of 5,043 cases. Prenat Diagn 2007;27:180-3.

상세보기
Eddleman KA, Malone FD, Sullivan L, Dukes K, Berkowitz RL, Kharbutli Y, et al. Pregnancy loss rates after midtrimester amniocentesis. Obstet Gynecol 2006;108:1067-72.

상세보기
Tabor A, Philip J, Madsen M, Bang J, Obel EB, Norgaard-Pedersen B. Randomised controlled trial of genetic amniocentesis in 4606 low-risk women. Lancet 1986;1:1287-93.
Mujezinovic F, Alfirevic Z. Procedure-related complications of amniocentesis and chorionic villus sampling. Obstet Gynecol 2007;110:687-94.

상세보기
Tabor A, Vestergaard CH, Lidegaard O. Fetal loss rate after chorionic villus sampling and amniocentesis: an 11-year national registry study. Ultrasound Obstet Gynecol 2009;34:19-24.
Kwon HK, Cho JS, Park YW, Kim SK, Yang YH. Clinical analysis of midtrimester amniocentesis. Korean J Obstet Gynecol 2001;44:674-8.
Philip J, Bang J. Outcome of pregnancy after amniocenfesis for chromosome analysis. Br Med J 1978;2:1183-4.

상세보기
O'Brien WF. Midtrimester genetic amniocentesis : a review of the fetal risks. J Reprod Med 1984;29:59-63.

상세보기

LOADING...

내보내기 구분	파일저장 인쇄 메일전송
구성항목	기본정보 상세정보 관리번호, 논문명, 저널/프로시딩명, 저자 , 발행년, 권, 호, 시작페이지, 끝페이지, 발행기관 관리번호, 논문명, 대등논문명, 저자 , 저널/프로시딩명, 발행기관, 발행년, 발행언어, 권, 호, 시작페이지, 끝페이지, ISBN, ISSN, 주제분야, 키워드, 초록(한글), 초록(영문), 저자(소속기관)
저장형식	Text(ASCII format) Excel format RefWorks Direct Export RIS format (for Reference Manager, ProCite, EndNote), Scholar's Aids, Mendeley
메일정보	받는사람 (필수) @ 보내는사람 (선택) @ 제목 내용 KISTI 검색결과 이메일 서비스
안내	총 건의 자료가 검색되었습니다. 다운받으실 자료의 인덱스를 입력하세요. (1-10,000) 검색결과의 순서대로 최대 10,000건 까지 다운로드가 가능합니다. 데이타가 많을 경우 속도가 느려질 수 있습니다.(최대 2~3분 소요) 다운로드 파일은 UTF-8 형태로 저장됩니다. 파일의 내용이 제대로 보이지 않을실 때는 웹브라우저 상단의 보기 -> 인코딩 -> 자동선택 여부를 확인하십시오. ~ Text(ASCII format) Excel format

연합인증