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NTIS 바로가기韓國韓醫學硏究院論文集 = Korean journal of oriental medicine, v.18 no.2 = no.35, 2012년, pp.151 - 157
전우현 (대구한의대학교 한의과대학) , 정인권 (대구한의대학교 한의과대학) , 강수진 (대구한의대학교 방제과학 글로벌 연구센터) , 구세광 (대구한의대학교 한의과대학) , 이영준 (대구한의대학교 한의과대학)
In this research, the genotoxic effect of Bupleuri Radix (BR), the dried roots of Bupleurum falcatum Linne has been traditionally used as anti-inflammatory agent, was evaluated using the mouse micronucleus test. BR aqueous extract (yield = 16.52%) was administered once a day for 2 continuous days by...
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Lee JE, Kim HJ, Choi EK, Chai HY, Yun YW, Kim DJ, Nam SY, Lee BJ, Ahn BW, Kang HG, Kim YB. Four-week repeated-dose toxicity study on Pinellia Extract. Korean J Lab Anim Sci. 2003;19:127-141.
Renner HW. In vivo effects of single or combined dietary antimutagens on mutagen-induced chromosomal aberrations. Mutat Res. 1990;244(2):185-188.
Korea Food and Drug Administration. Testing Guidelines for Safety Evaluation of Drugs, 2009-116 (2009).
Kalantari H, Larki A, Latifi SM. The genotoxicity study of garlic and pasipy herbal drops by peripheral blood micronucleus test. Acta Physiol Hung. 2007;94(3):261-266.
Lee B, Shim I, Lee H, Hahm DH. Effect of Bupleurum falcatum on the stress-induced impairment of spatial working memory in rats. Biol Pharm Bull. 2009;32(8):1392-1398.
Cho BS, Kim SD, Park JK, Chung JH, Hong MS, Lee BC, Ihm CG. Effects of Bupleurum falcatum and its combination with an angiotensin II receptor blocker on cytokine and chemokine expression in human mesangial cells. Phytother Res. 2010;24(3):339-343.
Yamamoto M, Kumagai A, Yamamura Y. Structure and actions of saikosaponins isolated from Bupleurum falcatum L. I. Anti-inflammatory action of saikosaponins. Arzneimittel-Forschung. 1975;25(7):1021-1023.
Yamamoto M, Kumagai A, Yamamura Y. Structure and action of saikosaponins isolated from Bupleurum falcatum L. II. Metabolic actions of saikosaponins, especially a plasma cholesterol-lowering action. Arzneimittel-Forschung. 1975;25(8):1240-1243.
Abe H, Sakaguchi M, Yamada M, Arichi S, Odashima S. Pharmacological actions of saikosaponins isolated from Bupleurum falcatum. 1. Effects of saikosaponins on liver function. Planta medica. 1980;40(4):366-372.
Lin CC, Chiu HF, Yen MH, Wu CC, Chen MF. The pharmacological and pathological studies on Taiwan folk medicine (III): The effects of bupleurum kaoi and cultivated bupleurum falcatum var. komarowi. The American journal of Chinese medicine. 1990;18(3-4):105-112.
Hattori T, Ito M, Suzuki Y. [Studies on antinephritic effects of plant components in rats (1). Effects of saikosaponins original-type anti-GBM nephritis in rats and its mechanisms]. Nihon yakurigaku zasshi Folia pharmacologica Japonica. 1991;97(1):13-21.
Sakurai MH, Matsumoto T, Kiyohara H, Yamada H. B-cell proliferation activity of pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. and its structural requirement. Immunology. 1999; 97(3):540-547.
Guo Y, Matsumoto T, Kikuchi Y, Ikejima T, Wang B, Yamada H. Effects of a pectic polysaccharide from a medicinal herb, the roots of Bupleurum falcatum L. on interleukin 6 production of murine B cells and B cell lines. Immunopharmacology. 2000;49(3):307-316.
Matsumoto T, Sun XB, Hanawa T, Kodaira H, Ishii K, Yamada H. Effect of the antiulcer polysaccharide fraction from Bupleurum falcatum L. on the healing of gastric ulcer induced by acetic acid in rats. Phytother Res. 2002;16(1):91-93.
Chang WC, Hsu FL. Inhibition of platelet activation and endothelial cell injury by flavan-3-ol and saikosaponin compounds. Prostaglandins, leukotrienes, and essential fatty acids. 1991;44(1):51-56.
Nose M, Amagaya S, Ogihara Y. Corticosterone secretion-inducing activity of saikosaponin metabolites formed in the alimentary tract. Chemical & pharmaceutical bulletin. 1989;37(10): 2736-2740.
Abe H, Sakaguchi M, Odashima S, Arichi S. Protective effect of saikosaponin-d isolated from Bupleurum falcatum L. on CCl4-induced liver injury in the rat. Naunyn-Schmiedeberg's archives of pharmacology. 1982;320(3):266-271.
Niikawa M, Sakai Y, Ose Y, Sato T, Nagase H, Kito H, Sato M, Mizuno M. Enhancement of the mutagenicity of Trp-P-1, Trp-P-2 and benzo[a]pyrene by bupleuri radix extract. Chemical & pharmaceutical bulletin. 1990;38(7): 2035-2039.
Organization for Economic Co-Operation and Development (Ed.) 474.(1997) OECD Guideline for the Testing of Chemicals, No. 474: Mammalian Erythrocyte Micronucleus Test.
Irwin S. Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse. Psychopharmacologia. 1968;13(3): 222-257.
Dourish CT. Effects of drugs on spontaneous motor activity. Greenshaw AJ, Dourish CT, editors. Clifton: Humana Press; 1987. 325-334 p.
Schmid W. The micronucleus test. Mutat Res. 1975;31(1):9-15.
Heddle JA, Stuart E, Salamone MF. The bone marrow micronucleus test. In: Kilbey BJ, Legator M, Nichols W, Ramel C, editors. Handbook of mutagenicity test procedures. Amsterdam: Elsevier; 1984. p. 441-457.
Levene A. Pathological factors influencing excision of tumours in the head and neck. Part I. Clinical otolaryngology and allied sciences. 1981;6(2):145-151.
Ludbrook J. Update: microcomputer statistics packages. A personal view. Clinical and experimental pharmacology & physiology. 1997;24(3-4):294-296.
Matter B, Schmid W. Trenimon-induced chromosomal damage in bone-marrow cells of six mammalian species, evaluated by the micronucleus test. Mutat Res. 1971;12(4): 417-425.
Heddle JA. A rapid in vivo test for chromosomal damage. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 1973;18(2):187-190.
von Ledebur M, Schmid W. The micronucleus test. Methodological aspects. Mutat Res. 1973;19(1):109-117.
Heddle JA, Hite M, Kirkhart B, Mavournin K, MacGregor JT, Newell GW, Salamone MF. The induction of micronuclei as a measure of genotoxicity: a report of the US Environmental Protection Agency Gene-Tox Program. Mutation Research/Reviews in Genetic Toxicology. 1983;123(1):61-118.
Ashby J. Is there a continuing role for the intraperitoneal injection route of exposure in short-term rodent genotoxicity assays? Mutation research. 1985;156(3):239.
Grochow L, Perry M. Covalent DNA-binding drugs. In: Perry M, editor. The Chemotherapy Source Book. Baltimore: Williams & Wilkins; 1997. p. 293-316.
Miyauchi A, Hiramine C, Tanaka S, Hojo K. Differential effects of a single dose of cyclophosphamide on T cell subsets of the thymus and spleen in mice: flow cytofluorometry analysis. The Tohoku journal of experimental medicine. 1990;162(2):147-167.
El-Bayoumy K. The protective role of selenium on genetic damage and on cancer. Mutat Res. 2001;475(1-2):123-139.
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