Lee, Jun Wook
(Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine)
,
Kim, Young Joon
(Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine)
,
Kim, Hoon
(Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine)
,
Nam, Sang Hyun
(Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine)
,
Shin, Bo Moon
(Department of Laboratory Medicine, Sanggye Paik Hospital, Inje University College of Medicine)
,
Choi, Young Woong
(Department of Plastic and Reconstructive Surgery, Sanggye Paik Hospital, Inje University College of Medicine)
Background Pathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture. Methods This was ...
Background Pathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture. Methods This was a prospective, double-blind, randomized study about the rate of nasal carriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software. Results Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci (CNS) were the most cultured bacteria in 127 (66.84%) of the 190 total patients after excluding 10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci (MRCNS) were found in 48 (25.26%). Staphylococcus aureus was the second most identified pathogen, found in 36 (18.95%), followed by 7 cases (3.68%) of methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate of MRSA in the females was higher than that in the males (RR=4.70; 95% CI, 1.09-20.18), but other demographic factors had no effect on the prevalence rate of MRSA and MRCNS. Conclusions The prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications. Additional research is needed on the potential connections between clinical factors and microbiological data.
Background Pathogens in the nasal cavity during nasal surgery could lead to a systemic infectious condition, such as bacteremia, nosocomial infection, or toxic shock syndrome. However, there is no research about the prevalence of nasal carriage in patients with nasal bone fracture. Methods This was a prospective, double-blind, randomized study about the rate of nasal carriage in 200 patients with nasal bone fracture in Korea. Nasal secretions were taken from both the middle nasal meatus and colonized. All analyses were carried out using SPSS software. Results Pathogens were identified in 178 of the 200 cases. Coagulase-negative staphylococci (CNS) were the most cultured bacteria in 127 (66.84%) of the 190 total patients after excluding 10 cases of contaminated samples, and methicillin-resistant coagulase-negative staphylococci (MRCNS) were found in 48 (25.26%). Staphylococcus aureus was the second most identified pathogen, found in 36 (18.95%), followed by 7 cases (3.68%) of methicillin-resistant Staphylococcus aureus (MRSA). The prevalence rate of MRSA in the females was higher than that in the males (RR=4.70; 95% CI, 1.09-20.18), but other demographic factors had no effect on the prevalence rate of MRSA and MRCNS. Conclusions The prevalence rate of these pathogens in patients with nasal bone fracture in Korea was similar to other reports. However, few studies have addressed the prevalence rate of CNS and MRCNS in accordance with risk factors or the change in prevalence according to specific prophylaxis against infectious complications. Additional research is needed on the potential connections between clinical factors and microbiological data.
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대상 데이터
A prospective study was conducted on 200 patients at our department in Korea from July 1, 2010 to March 31, 2011. There were no exclusion criteria except cases in which patients could not be operated on under general anesthesia.
Pathogens were identified in the nasal cavities of 178 of the 200 patients (Table 1). 10 samples were contaminated, and those were excluded from the total number of patients.
이론/모형
The unpaired Student’s t-test was used to analyze continuous data, and either the 2-tailed chi-squared test (χ2 test) or Fisher’s exact test was used to analyze categorical data, where appropriate, with 2-tailed relative risk (RR).
성능/효과
aureus isolates. By univariate analysis, colonization of MRSA in the females was 14.28% higher than that in the males (RR = 4.70; 95% CI, 1.09-20.18), and the prevalence rate of MRSA was 7.49% more in the females than in the males (P = 0.023). MRSA was more prevalent in the severely fractured group and epistaxis group (1.
CNS were evaluated as a pathogen in this study [9]. CNS were the most cultured bacteria, found in 127 (66.84%) of the 190 total patients after the 10 contaminated cases had been excluded, and MRCNS was found in 48 (25.26%). S.
68%). In 14 subjects (7.37%), various Gram-negative rods were identified, among them Enterobacter aerogenes, Raoultella planticola, the Proteus vulgaris group, Haemophilus influenza, Serratia marcescens, and Streptococcus mitis. Fungus was found in 1 sample and anaerobes were not found in the study.
In conclusion, the prevalence rate of pathogens such as S. aureus, MRSA, CNS, and MRCNS in patients with nasal bone fracture in Korea was similar to those of other reports. It remains necessary to investigate the correlation between microbiological test data and many clinical factors such as infectious complications and management.
aureus, MRSA, CNS, and MRCNS colonization are shown in Tables 3, 4. The mean and standard deviation of the patient age and duration (day) from trauma to culture were calculated, and a comparison of prevalence by sex was measured by relative risk. S.
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