최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Radiation oncology journal : ROJ, v.31 no.2, 2013년, pp.57 - 65
Ahn, Ki Jung (Department of Radiation Oncology, Inje University College of Medicine) , Lee, Hyung Sik (Department of Radiation Oncology, Dong-A University College of Medicine) , Bai, Se Kyung (Department of Biochemistry, Kangwon National University) , Song, Chang Won (Radiobiology Laboratory, Department of Therapeutic Radiology, University of Minnesota Medical School)
Beta-lapachone (
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
1 Pardee AB Li YZ Li CJ Cancer therapy with beta-lapachone Curr Cancer Drug Targets 2002 2 227 242 12188909
2 Planchon SM Wuerzberger S Frydman B Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response Cancer Res 1995 55 3706 3711 7641180
3 Park HJ Ahn KJ Ahn SD Susceptibility of cancer cells to beta-lapachone is enhanced by ionizing radiation Int J Radiat Oncol Biol Phys 2005 61 212 219 15629614
4 Kim EJ Ji IM Ahn KJ Synergistic effect of ionizing radiation and beta-Lapachone against RKO human colon adenocarcinoma cells Cancer Res Treat 2005 37 183 190 19956501
5 Suzuki M Amano M Choi J Synergistic effects of radiation and beta-lapachone in DU-145 human prostate cancer cells in vitro Radiat Res 2006 165 525 531 16669706
6 Choi EK Terai K Ji IM Upregulation of NAD(P)H:quinine oxidoreductase by radiation potentiates the effect of bioreductive beta-lapachone on cancer cells Neoplasia 2007 9 634 642 17786182
7 Terai K Dong GZ Oh ET Cisplatin enhances the anticancer effect of beta-lapachone by upregulating NQO1 Anticancer Drugs 2009 20 901 909 19738461
8 Park HJ Choi EK Choi J Heat-induced up-regulation of NAD(P)H:quinone oxidoreductase potentiates anticancer effects of beta-lapachone Clin Cancer Res 2005 11 8866 8871 16361576
9 Song CW Chae JJ Choi EK Anti-cancer effect of bio-reductive drug beta-lapachon is enhanced by activating NQO1 with heat shock Int J Hyperthermia 2008 24 161 169 18283592
10 Dong GZ Youn H Park MT Heat shock increases expression of NAD(P)H:quinone oxidoreductase (NQO1), mediator of beta-lapachone cytotoxicity, by increasing NQO1 gene activity and via Hsp70-mediated stabilisation of NQO1 protein Int J Hyperthermia 2009 25 477 487 19657853
11 Hori T Kondo T Lee H Song CW Park HJ Hyperthermia enhances the effect of β-Lapachone to cause γH2AX formations and cell death in human osteosarcoma cells Int J Hyperthermia 2011 27 53 62 21070139
12 Planchon SM Pink JJ Tagliarino C Bornmann WG Varnes ME Boothman DA beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3 Exp Cell Res 2001 267 95 106 11412042
13 Pink JJ Planchon SM Tagliarino C Varnes ME Siegel D Boothman DA NAD(P)H:quinone oxidoreductase activity is the principal determinant of beta-lapachone cytotoxicity J Biol Chem 2000 275 5416 5424 10681517
14 Pink JJ Wuerzberger-Davis S Tagliarino C Activation of a cysteine protease in MCF-7 and T47D breast cancer cells during beta-lapachone-mediated apoptosis Exp Cell Res 2000 255 144 155 10694431
15 Tagliarino C Pink JJ Dubyak GR Nieminen AL Boothman DA Calcium is a key signaling molecule in beta-lapachone-mediated cell death J Biol Chem 2001 276 19150 19159 11279125
16 Wuerzberger SM Pink JJ Planchon SM Byers KL Bornmann WG Boothman DA Induction of apoptosis in MCF-7:WS8 breast cancer cells by beta-lapachone Cancer Res 1998 58 1876 1885 9581828
17 Huang L Pardee AB beta-lapachone induces cell cycle arrest and apoptosis in human colon cancer cells Mol Med 1999 5 711 720 10656873
18 Li Y Sun X LaMont JT Pardee AB Li CJ Selective killing of cancer cells by beta-lapachone: direct checkpoint activation as a strategy against cancer Proc Natl Acad Sci U S A 2003 100 2674 2678 12598645
19 Boothman DA Trask DK Pardee AB Inhibition of potentially lethal DNA damage repair in human tumor cells by beta-lapachone, an activator of topoisomerase I Cancer Res 1989 49 605 612 2535961
20 Hueber A Esser P Heimann K Kociok N Winter S Weller M The topoisomerase I inhibitors, camptothecin and beta-lapachone, induce apoptosis of human retinal pigment epithelial cells Exp Eye Res 1998 67 525 530 9878214
21 Li CJ Averboukh L Pardee AB beta-Lapachone, a novel DNA topoisomerase I inhibitor with a mode of action different from camptothecin J Biol Chem 1993 268 22463 22468 8226754
22 Weller M Winter S Schmidt C Topoisomerase-I inhibitors for human malignant glioma: differential modulation of p53, p21, bax and bcl-2 expression and of CD95-mediated apoptosis by camptothecin and beta-lapachone Int J Cancer 1997 73 707 714 9398050
23 Frydman B Marton LJ Sun JS Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones Cancer Res 1997 57 620 627 9044837
24 Krishnan P Bastow KF Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives alpha-lapachone and beta-lapachone Cancer Chemother Pharmacol 2001 47 187 198 11320661
25 Li CJ Li YZ Pinto AV Pardee AB Potent inhibition of tumor survival in vivo by beta-lapachone plus taxol: combining drugs imposes different artificial checkpoints Proc Natl Acad Sci U S A 1999 96 13369 13374 10557327
26 Begleiter A Fourie J Induction of NQO1 in cancer cells Methods Enzymol 2004 382 320 351 15047110
27 Joseph P Xie T Xu Y Jaiswal AK NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer Oncol Res 1994 6 525 532 7620221
28 Joseph P Jaiswal AK NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase Proc Natl Acad Sci U S A 1994 91 8413 8417 8078896
29 Jaiswal AK Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases Arch Biochem Biophys 2000 375 62 68 10683249
30 Cullen JJ Hinkhouse MM Grady M Dicumarol inhibition of NADPH:quinone oxidoreductase induces growth inhibition of pancreatic cancer via a superoxide-mediated mechanism Cancer Res 2003 63 5513 5520 14500388
31 Monks TJ Hanzlik RP Cohen GM Ross D Graham DG Quinone chemistry and toxicity Toxicol Appl Pharmacol 1992 112 2 16 1733045
32 Riley RJ Workman P DT-diaphorase and cancer chemotherapy Biochem Pharmacol 1992 43 1657 1669 1575764
33 Rauth AM Goldberg Z Misra V DT-diaphorase: possible roles in cancer chemotherapy and carcinogenesis Oncol Res 1997 9 339 349 9406240
34 Ross D Siegel D NAD(P)H:quinone oxidoreductase 1 (NQO1, DT-diaphorase), functions and pharmacogenetics Methods Enzymol 2004 382 115 144 15047100
35 Talalay P Mechanisms of induction of enzymes that protect against chemical carcinogenesis Adv Enzyme Regul 1989 28 237 250 2696344
36 Jaiswal AK Jun and Fos regulation of NAD(P)H: quinone oxidoreductase gene expression Pharmacogenetics 1994 4 1 10 8004128
37 Keyes SR Fracasso PM Heimbrook DC Rockwell S Sligar SG Sartorelli AC Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1 Cancer Res 1984 44 5638 5643 6437671
38 Pan SS Andrews PA Glover CJ Bachur NR Reductive activation of mitomycin C and mitomycin C metabolites catalyzed by NADPH-cytochrome P-450 reductase and xanthine oxidase J Biol Chem 1984 259 959 966 6319393
39 Hodnick WF Sartorelli AC Reductive activation of mitomycin C by NADH:cytochrome b5 reductase Cancer Res 1993 53 4907 4912 8402680
40 Siegel D Franklin WA Ross D Immunohistochemical detection of NAD(P)H:quinone oxidoreductase in human lung and lung tumors Clin Cancer Res 1998 4 2065 2070 9748120
41 Belinsky M Jaiswal AK NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues Cancer Metastasis Rev 1993 12 103 117 8375015
42 Cresteil T Jaiswal AK High levels of expression of the NAD(P)H: quinine oxidoreductase (NQO1) gene in tumor cells compared to normal cells of the same origin Biochem Pharmacol 1991 42 1021 1027 1651729
43 Long DJ 2nd Gaikwad A Multani A Disruption of the NAD(P)H:quinone oxidoreductase 1 (NQO1) gene in mice causes myelogenous hyperplasia Cancer Res 2002 62 3030 3036 12036909
44 Dhakshinamoorthy S Jaiswal AK Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene Oncogene 2001 20 3906 3917 11439354
45 Winski SL Swann E Hargreaves RH Relationship between NAD(P)H:quinone oxidoreductase 1 (NQO1) levels in a series of stably transfected cell lines and susceptibility to antitumor quinones Biochem Pharmacol 2001 61 1509 1516 11377380
46 Docampo R Cruz FS Boveris A Muniz RP Esquivel DM beta-Lapachone enhancement of lipid peroxidation and superoxide anion and hydrogen peroxide formation by sarcoma 180 ascites tumor cells Biochem Pharmacol 1979 28 723 728 222291
47 O'Brien PJ Molecular mechanisms of quinone cytotoxicity Chem Biol Interact 1991 80 1 41 1913977
48 Boveris A Docampo R Turrens JF Stoppani AO Effect of beta-lapachone on superoxide anion and hydrogen peroxide production in Trypanosoma cruzi Biochem J 1978 175 431 439 217340
49 Chau YP Shiah SG Don MJ Kuo ML Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells Free Radic Biol Med 1998 24 660 670 9559879
50 Molina Portela MP Stoppani AO Redox cycling of beta-lapachone and related o-naphthoquinones in the presence of dihydrolipoamide and oxygen Biochem Pharmacol 1996 51 275 283 8573194
※ AI-Helper는 부적절한 답변을 할 수 있습니다.