[논문]우산고로쇠의 향장효과

손상현; 이상원; 신유수; 김형돈; 양승옥; 김승유; 김영옥

doi:10.7783/kjmcs.2013.21.4.262

우산고로쇠의 향장효과
The Effect of Cosmetic on Anti-Wrinkle of Acer mono Sap 원문보기

韓國藥用作物學會誌 = Korean journal of medicinal crop science, v.21 no.4, 2013년, pp.262 - 267

손상현 (농촌진흥청 국립원예특작과학원 인삼특작부) , 이상원 (농촌진흥청 국립원예특작과학원 인삼특작부) , 신유수 (농촌진흥청 국립원예특작과학원 인삼특작부) , 김형돈 (농촌진흥청 국립원예특작과학원 인삼특작부) , 양승옥 (농촌진흥청 국립원예특작과학원 인삼특작부) , 김승유 (농촌진흥청 국립원예특작과학원 인삼특작부) , 김영옥 (농촌진흥청 국립원예특작과학원 인삼특작부)

Abstract ▼ AI-Helper

The purpose of this study was to research for anti-oxidation and anti-wrinkle effects of Acar mono Sap (AM). To cosmetic effect of AM, safety effect (MTT assay), anti-wrinkle effect (elastase, MMP-1 inhibition assay) and anti-oxidant effect (DPPH assay) were measured. When water extract of AM was used for cell viability, it was over 100% at 6% (6 ml/100 ml in phosphate buffer) concentration. AM showed 45.7% elastase inhibition and 23.7% MMP-1 inhibition at 50% (50 ml/100 ml in phosphate buffer) concentration so that it had good anti-wrinkle characteristic. And AM showed 68.9% antioxidation capacity at 50% concentration by using a DPPH assay. Consequently, AM can be used as natural materials or additives for human skin owing to their beneficial biologic functions, including the anti-wrinkle effect, for cosmetic compositions.

주제어

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문제 정의

Thus, this study may be interesting to modern scientists to understand different approaches and processes that may be useful to progress research on promotive, preventive and therapeutic interventions generally on various degenerating conditions and aging. Therefore, the objectives of the present study was to evaluate its biological activities such as their antioxidant, anti-elastase, and anti-inflammatory activities for application to human skin.
AM was found to have the high elastase inhibition activity compared to adenosine which was used as a positive control. This research offered that AM would have potential as an anti-wrinkle agent for use in cosmetic products.

제안 방법

In order to investigate for wrinkle-care cosmetics, we screened free radical scavenging activities, elastase inhibition activities and MMP-1 assays. Other studies have demonstrated that chronic UV-A and UV-B radiation result in a significant increase in elastase-type enzyme activity (Imayama et al.
To study whether AM could induce cell viability, we checked cell viability using a MTT assay.

이론/모형

The procedures of cell viability assay were applied by the method of Mosmann (1983). Hs27 was obtained from the American Type Culture Collection (ATCC, Rockville, MD, USA).

후속연구

However, more systematic scientific studies to establish the safety and efficacy of medicinal herb in both rejuvenation and detoxification procedures are needed. Thus, this study may be interesting to modern scientists to understand different approaches and processes that may be useful to progress research on promotive, preventive and therapeutic interventions generally on various degenerating conditions and aging. Therefore, the objectives of the present study was to evaluate its biological activities such as their antioxidant, anti-elastase, and anti-inflammatory activities for application to human skin.

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우산고로쇠의 향장효과
The Effect of Cosmetic on Anti-Wrinkle of Acer mono Sap 원문보기

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우산고로쇠의 향장효과 The Effect of Cosmetic on Anti-Wrinkle of Acer mono Sap 원문보기

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The Effect of Cosmetic on Anti-Wrinkle of Acer mono Sap 원문보기

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