[논문]A New Paradigm Shift for the Green Synthesis of Antibacterial Silver Nanoparticles Utilizing Plant Extracts

Park, Youmie

doi:10.5487/tr.2014.30.3.169

A New Paradigm Shift for the Green Synthesis of Antibacterial Silver Nanoparticles Utilizing Plant Extracts 원문보기

Toxicological research, v.30 no.3, 2014년, pp.169 - 178

Park, Youmie (College of Pharmacy, Inje University)

Abstract ▼ AI-Helper

This review covers general information regarding the green synthesis of antibacterial silver nanoparticles. Owing to their antibacterial properties, silver nanoparticles are widely used in many areas, especially biomedical applications. In green synthesis practices, the chemical reducing agents are eliminated, and biological entities are utilized to convert silver ions to silver nanoparticles. Among the various biological entities, natural plant extracts have emerged as green reducing agents, providing eco-friendly routes for the preparation of silver nanomaterials. The most obvious merits of green synthesis are the increased biocompatibility of the resulting silver nanoparticles and the ease with which the reaction can be carried out. This review summarizes some of the plant extracts that are used to produce antibacterial silver nanoparticles. Additionally, background information regarding the green synthesis and antibacterial activity of silver nanoparticles is provided. Finally, the toxicological aspects of silver nanoparticles are briefly mentioned.

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가설 설정

Researchers have reported that four factors—pH, temperature, reaction time and the ratio of plant extracts to silver nitrate—affect the synthesis of AgNPs based on plant extracts (8,12). (1) By changing the pH, the charges of the biomolecules in extracts are altered. Because the Ag ion is a cation, the charge of the biomolecules also affects the synthesis of AgNPs.

제안 방법

There are extensive reviews that address this area (8-12). Instead, this review focuses on the preparation of antibacterial AgNPs by using plant extracts as reducing agents.

대상 데이터

We performed a green synthesis reaction for AgNPs by using extract of Caesalpinia sappan in both the absence and presence of stabilizers. The stabilizers used were a nonionic polymer (PVP) and cationic (CTAB), anionic (SDS, NaDDSS) and nonionic (Tween 20 and 80) surfactants (25). Among the tested stabilizers, CTAB-stabilized AgNPs were found to be the most potent antibacterial agents against 19 strains of MRSA (25).

성능/효과

The stabilizers used were a nonionic polymer (PVP) and cationic (CTAB), anionic (SDS, NaDDSS) and nonionic (Tween 20 and 80) surfactants (25). Among the tested stabilizers, CTAB-stabilized AgNPs were found to be the most potent antibacterial agents against 19 strains of MRSA (25). The bilayer shell of CTAB provides improved colloidal stability to the AgNPs, which is closely connected to their enhanced antibacterial activity against MRSA.

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