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NTIS 바로가기Journal of embryo transfer = 한국수정란이식학회지, v.30 no.3, 2015년, pp.121 - 128
이경진 (강원대학교 동물생명과학대학) , 이상희 (강원대학교 동물생명과학대학) , 주선호 (강원대학교 동물생명과학대학) , 김유진 (강원대학교 동물생명과학대학) , 양진우 (강원대학교 동물생명과학대학) , 이연주 (강원대학교 동물생명과학대학) , 황보용 (강원대학교 동물생명과학대학) , 이승형 (강원대학교 동물생명과학대학) , 이승태 (강원대학교 동물생명과학대학) , 이은송 (강원대학교 수의과대학) , 박춘근 (강원대학교 동물생명과학대학)
The objective of this study was to evaluate the efficiency of sperm cryosurvival in boar sperm separated by Percoll containing antioxidant enzymes. The boar semen was collected into a pre-warmed (
핵심어 | 질문 | 논문에서 추출한 답변 |
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정액의 동결 보존은 어떠한 특징을 가지고 있는 기술인가? | 정액의 동결 보존은 정자를 초저온에서 보관하는 기술로, 반영구적인 보관이 가능하여 우수한 형질의 유전자원을 보존할 수 있는 특징을 가지고 있다. 이러한 장점으로 멸종위기동물의 유전자원 보존과 가축의 개량 및 생산성 향상에 크게영향을 미쳤다(Sieme와 Oldenhof, 2015). | |
정액의 동결과정 중 다양한 물리적, 화학적 스트레스에 노출되어 세포에서 생성되는 과도한 활성 산소는 정자에 어떤 영향을 미치는가? | 특히 돼지 정자는 다른 종에 비해 세포막 내 다중불포화지방산의 농도가 높기 때문에 산화적 충격에 더 민감하다(Strzezek 등, 2004). 이러한 활성 산소는 정자의 생존율과 운동성의 감소, 세포막 손상 및 DNA 손상에 영향을 미치게 되어, 최종적으로 정자의 수정능력을 감소시키게 된다(Knox 등, 2015). | |
돼지 정자가 산화적 충격에 더 민감한 이유는? | 동결과정 중 다양한물리적, 화학적 스트레스에 노출되어 세포에서 생성되는 과도한 활성 산소 종에 의해 정자가 손상을 받게 된다(Santiani 등, 2014). 특히 돼지 정자는 다른 종에 비해 세포막 내 다중불포화지방산의 농도가 높기 때문에 산화적 충격에 더 민감하다(Strzezek 등, 2004). 이러한 활성 산소는 정자의 생존율과 운동성의 감소, 세포막 손상 및 DNA 손상에 영향을 미치게 되어, 최종적으로 정자의 수정능력을 감소시키게 된다(Knox 등, 2015). |
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