Kim, Jin-Tae
(Dental Materials Research Center, Neobiotech Co., Ltd.)
,
Kim, Byoung Soo
(Dental Materials Research Center, Neobiotech Co., Ltd.)
,
Jeong, Hee Seok
(Dental Materials Research Center, Neobiotech Co., Ltd.)
,
Heo, Young Ku
(Dental Materials Research Center, Neobiotech Co., Ltd.)
,
Shin, Sang-Wan
(Institute for Clinical Dental Research, Korea University)
,
Lee, Jeong-Yol
(Institute for Clinical Dental Research, Korea University)
,
Shim, Young Ho
(Institute for Clinical Dental Research, Korea University)
,
Lee, Deuk Yong
(Department of Biomedical Engineering, Daelim University)
Titanium barrier membranes are prepared to investigate the effect of surface-treatments, such as machining, electropolishing, anodizing, and electropolishing + TiN coating, on the biocompatibility and physical properties of the membranes. The surface roughness (Ra) of the membrane decreases from mac...
Titanium barrier membranes are prepared to investigate the effect of surface-treatments, such as machining, electropolishing, anodizing, and electropolishing + TiN coating, on the biocompatibility and physical properties of the membranes. The surface roughness (Ra) of the membrane decreases from machining ($0.37{\pm}0.09{\mu}m$), TiN coating ($0.22{\pm}0.09{\mu}m$), electropolishing ($0.20{\pm}0.03{\mu}m$), to anodizing ($0.15{\pm}0.03{\mu}m$). The highest ductility (24.50 %) is observed for the electropolished Ti membrane. No evidence of causing cell lysis or toxicity is found for the membranes regardless of the surface-treatments. Cell adhesion results of L-929 and MG-63 show that the machined Ti membrane exhibits the highest cell adhesion while the electropolished membrane is the best membrane for the L-929 cell proliferation after 7 days. However, no appreciable difference in MG-63 cell proliferation among variously surface-treated membranes is detected, suggesting that the electropolished Ti membrane is likely to be the best membrane due to the synergic combination of tailored flexibility and excellent fibroblast proliferation.
Titanium barrier membranes are prepared to investigate the effect of surface-treatments, such as machining, electropolishing, anodizing, and electropolishing + TiN coating, on the biocompatibility and physical properties of the membranes. The surface roughness (Ra) of the membrane decreases from machining ($0.37{\pm}0.09{\mu}m$), TiN coating ($0.22{\pm}0.09{\mu}m$), electropolishing ($0.20{\pm}0.03{\mu}m$), to anodizing ($0.15{\pm}0.03{\mu}m$). The highest ductility (24.50 %) is observed for the electropolished Ti membrane. No evidence of causing cell lysis or toxicity is found for the membranes regardless of the surface-treatments. Cell adhesion results of L-929 and MG-63 show that the machined Ti membrane exhibits the highest cell adhesion while the electropolished membrane is the best membrane for the L-929 cell proliferation after 7 days. However, no appreciable difference in MG-63 cell proliferation among variously surface-treated membranes is detected, suggesting that the electropolished Ti membrane is likely to be the best membrane due to the synergic combination of tailored flexibility and excellent fibroblast proliferation.
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제안 방법
The surface roughness (arithmetic mean deviation of the profile, Ra) is examined by the laser surface roughness tester to investigate the effect of surface roughness on the degree of GBR and the biocompatibility between the Ti membrane surface and the gingival tissue. The surface-treated Ti barrier membranes are reported to replace the deficient and infected alveolar bone and provide the sufficient space underneath the membrane.
대상 데이터
The test extract is placed onto two separate confluent monolayers of L-929 mouse fibroblast cells (1 × 105 cells/ml) propagated in 5 % CO2.
데이터처리
For analyses of results, statistical calculations such as t-test (p < 0.05) and one-way analysis of variance (ANOVA, p < 0.001) are employed to analyze the results [10, 11].
참고문헌 (16)
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