최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of microbiology and biotechnology, v.25 no.5, 2015년, pp.648 - 657
Kim, Min-Je (Department of Bioscience and Biotechnology, Bio) , Kwon, Sae-Bom (Department of Bioscience and Biotechnology, Bio) , Ham, Seung Hoon (Department of Laboratory Animal Medicine, Veterinary Science Research Institute, College of Veterinary Medicine, Konkuk University) , Jeong, Eui-Suk (Department of Laboratory Animal Medicine, Veterinary Science Research Institute, College of Veterinary Medicine, Konkuk University) , Choi, Yang-Kyu (Department of Laboratory Animal Medicine, Veterinary Science Research Institute, College of Veterinary Medicine, Konkuk University) , Choi, Kang Duk (Graduate School of Future Convergence Technology, Genomic Informatics Center, Hankyong National University) , Hong, Jin Tae (College of Pharmacy, Chungbuk Nation University) , Jung, Seung Hyun (Oriental Medical Hospital, Dongguk University) , Yoon, Do-Young (Department of Bioscience and Biotechnology, Bio)
H9, a novel herbal extract, demonstrated cytotoxicity in A549 non-small cell lung cancer (NSCLC) cell lines. In this study, we investigated whether H9, and/or co-treatment with an anticancer drug, pemetrexed (PEM), inhibited tumor growth in BALB/c nude mice models bearing A549 NSCLC cells. The mice ...
Ashkenazi A, Dixit VM. 1998. Death receptors: signaling and modulation. Science 281: 1305-1308.
Azrak RG, Cao S, Slocum HK, Toth K, Durrani FA, Yin MB, et al. 2004. Therapeutic synergy between irinotecan and 5-fluorouracil against human tumor xenografts. Clin. Cancer Res. 10: 1121-1129.
Ban JO, Lee HS, Jeong HS, Song S, Hwang BY, Moon DC, et al. 2009. Thiacremonone augments chemotherapeutic agentinduced growth inhibition in human colon cancer cells through inactivation of nuclear factor-{kappa}B. Mol. Cancer Res. 7: 870-879.
Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, et al. 1999. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell 96: 857-868.
Butt MS, Sultan MT. 2009. Green tea: nature's defense against malignancies. Crit. Rev. Food Sci. Nutr. 49: 463-473.
Cai Y, Luo Q, Sun M, Corke H. 2004. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sci. 74: 2157-2184.
Chilin A, Battistutta R, Bortolato A, Cozza G, Zanatta S, Poletto G, et al. 2008. Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships. J. Med. Chem. 51: 752-759.
Ciechomska I, Pyrzynska B, Kazmierczak P, Kaminska B. 2003. Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells. Oncogene 22: 7617-7627.
Costi MP, Ferrari S, Venturelli A, Calo S, Tondi D, Barlocco D. 2005. Thymidylate synthase structure, function and implication in drug discovery. Curr. Med. Chem. 12: 2241-2258.
Datta SR, Brunet A, Greenberg ME. 1999. Cellular survival: a play in three Akts. Genes Dev. 13: 2905-2927.
Donnelly AC, Mays JR, Burlison JA, Nelson JT, Vielhauer G, Holzbeierlein J, Blagg BS. 2008. The design, synthesis, and evaluation of coumarin ring derivatives of the novobiocin scaffold that exhibit antiproliferative activity. J. Org. Chem. 73: 8901-8920.
Fulda S, Debatin KM. 2006. Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy. Oncogene 25: 4798-4811.
Galluzzo P, Marino M. 2006. Nutritional flavonoids impact on nuclear and extranuclear estrogen receptor activities. Genes Nutr. 1: 161-176.
Giovannetti E, Honeywell R, Hanauske AR, Tekle C, Kuenen B, Sigmond J, et al. 2010. Pharmacological aspects of the enzastaurin-pemetrexed combination in non-small cell lung cancer (NSCLC). Curr. Drug Targets 11: 12-28.
Green DR. 2000. Apoptotic pathways: paper wraps stone blunts scissors. Cell 102: 1-4.
Guo J, Wu H, Weng X, Yan J, Bi K. 2003. Studies on extraction and isolation of active constituents from Psoralen corylifolia L. and the antitumor effect of the constituents in vitro. Zhong Yao Cai 26: 185-187.
Hanahan D, Weinberg RA. 2000. The hallmarks of cancer. Cell 100: 57-70.
Hatakeyama Y, Kobayashi K, Nagano T, Tamura D, Yamamoto M, Tachihara M, et al. 2014. Synergistic effects of pemetrexed and amrubicin in non-small cell lung cancer cell lines: potential for combination therapy. Cancer Lett. 343: 74-79.
Hengartner MO. 2000. The biochemistry of apoptosis. Nature 407: 770-776.
Herbst RS, Heymach JV, Lippman SM. 2008. Lung cancer. N. Engl. J. Med. 359: 1367-1380.
Hwu JR, Lin SY, Tsay SC, De Clercq E, Leyssen P, Neyts J. 2011. Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus. J. Med. Chem. 54: 2114-2126.
Hwu JR, Singha R, Hong SC, Chang YH, Das AR, Vliegen I, et al. 2008. Synthesis of new benzimidazole-coumarin conjugates as anti-hepatitis C virus agents. Antiviral Res. 77: 157-162.
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. 2011. Global cancer statistics. CA Cancer J. Clin. 61: 69-90.
Kandaswami C, Lee LT, Lee PP, Hwang JJ, Ke FC, Huang YT, Lee MT. 2005. The antitumor activities of flavonoids. in vivo 19: 895-909.
Nagai H, Yasuda H, Hatachi Y, Xue D, Sasaki T, Yamaya M, et al. 2012. Nitric oxide (NO) enhances pemetrexed cytotoxicity via NOcGMP signaling in lung adenocarcinoma cells in vitro and in vivo. Int. J. Oncol. 41: 24-30.
Ng PL, Rajab NF, Then SM, Mohd Yusof YA, Wan Ngah WZ, Pin KY, Looi ML. 2014. Piper betle leaf extract enhances the cytotoxicity effect of 5-fluorouracil in inhibiting the growth of HT29 and HCT116 colon cancer cells. J. Zhejiang Univ. Sci. B 15: 692-700.
Pastorino JG, Tafani M, Farber JL. 1999. Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway. J. Biol. Chem. 274: 19411-19416.
Patnaik GK, Banaudha KK, Khan KA, Shoeb A, Dhawan BN. 1987. Spasmolytic activity of angelicin: a coumarin from Heracleum thomsoni. Planta Med. 53: 517-520.
Rahman MA, Kim NH, Yang H, Huh SO. 2012. Angelicin induces apoptosis through intrinsic caspase-dependent pathway in human SH-SY5Y neuroblastoma cells. Mol. Cell Biochem. 369: 95-104.
Sardari S, Mori Y, Horita K, Micetich RG, Nishibe S, Daneshtalab M. 1999. Synthesis and antifungal activity of coumarins and angular furanocoumarins. Bioorg. Med. Chem. 7: 1933-1940.
Scaffidi C, Fulda S, Srinivasan A, Friesen C, Li F, Tomaselli KJ, et al. 1998. Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17: 1675-1687.
Schiller JH, Harrington D, Belani CP, Langer C, Sandler A, Krook J, et al. 2002. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N. Engl. J. Med. 346: 92-98.
Shih C, Chen VJ, Gossett LS, Gates SB, MacKellar WC, Habeck LL, et al. 1997. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes. Cancer Res. 57: 1116-1123.
Sigmond J, Backus HH, Wouters D, Temmink OH, Jansen G, Peters GJ. 2003. Induction of resistance to the multitargeted antifolate pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. Biochem. Pharmacol. 66: 431-438.
Thornberry NA, Rano TA, Peterson EP, Rasper DM, Timkey T, Garcia-Calvo M, et al. 1997. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272: 17907-17911.
Zhuang L, Lee CS, Scolyer RA, McCarthy SW, Zhang XD, Thompson JF, Hersey P. 2007. Mcl-1, Bcl-XL and Stat3 expression are associated with progression of melanoma whereas Bcl-2, AP-2 and MITF levels decrease during progression of melanoma. Mod. Pathol. 20: 416-426.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.