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NTIS 바로가기The acupuncture = 대한침구의학회지, v.33 no.4, 2016년, pp.49 - 63
현민경 (동서한방병원 침구의학과) , 모민주 (동서한방병원 침구의학과) , 황두리 (동서한방병원 침구의학과) , 양태준 (동신대학교 한의과대학 침구의학교실) , 이정훈 (동신대학교 한의과대학 침구의학교실) , 이은지 (청연한방병원 침구의학과) , 윤태경 (부천자생한방병원 침구의학과) , 윤대환 (동신대학교 한의과대학 경혈학교실)
Objectives : This research was performed to investigate the effects of Jodeungsan pharmacopuncture(PA-J) of focal brain ischemia induced by middle cerebral artery occlusion(MCAO) in rats. Methods : The subjects were divided into 4 groups : control, acupuncture, pharmacopuncture PA-J1(11.43 mg / 250 ...
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핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
치매는 무엇인가? | 치매란 뇌조직의 변성 또는 노화, 혈관성 장애, 뇌손상, 중추신경계 감염, 독성 대사장애, 기타 신경계 질환 등의 원인으로 인해1) 뇌기능이 손상되면서 기억력, 언어 능력, 시공간파악능력, 판단력및 추상적 사고력 등의 인지기능이 전반적이고 지속적으로 저하되는 증상이다2). | |
치매를 원인 질환에 따라 분류하시오. | 치매는 원인 질환에 따라 알츠하이머형 치매, 혈관성 치매, 전측두엽성 치매 등으로 분류할 수 있는데3) 그중 알츠하이머형 치매와 혈관성 치매 모두에서 인지장애가 유발되는 병리적 기전에 비정상적인 뇌혈류 저하를 포함한 혈관 인자가 작용하며4)특히 우리나라와 일본에서는 서구보다 혈관성 치매가 더 흔하다고 알려져 있어5)혈관성 치매가 보다 중요하게 인식되고 있다. | |
국외에서 시행된 연구에서 약침의 효과는? | 釣藤散은 許叔微의 저서인《普濟本事方》9)에 처음 수록된 방제로서 平肝潛陽하는 효능이 있으며補氣健脾, 理氣化痰하는 약물이 배합되어 있어 氣虛挾痰을 바탕으로 한 肝風內動에 효과가 있는 처방이다10). 최근 釣藤散의 인지장애 개선 효과의 기전을 밝히는 연구들이 활발하게 이루어져 학습과 기억에 관련한 아세틸콜린을 증가시키는 효능과 신경보호능이 있는 것으로 보고되고 있다11-15). 그러나 이는 대부분 국외에서 시행된 연구들로 현재까지 국내 연구 발표는 부족한 실정이다. |
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