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Effects of Aqueous Extracts of Cynanchum wilfordii in Rat Models for Postmenopausal Hot Flush 원문보기

Preventive nutrition and food science, v.21 no.4, 2016년, pp.373 - 377  

Lee, Gyuok (Division of Food and Nutrition, Chonnam National University) ,  Choi, Chul-yung (Jeollanamdo Institute of Natural Resources Research) ,  Jun, Woojin (Division of Food and Nutrition, Chonnam National University)

Abstract AI-Helper 아이콘AI-Helper

Menopausal hot flushes (HFs), which manifest as a transient increase in skin temperature, occur most frequently in postmenopausal women, and sometimes negatively influence daily life. We investigated the effect of an aqueous extract of Cynanchum wilfordii (CWW) in a rat model of menopausal HFs, wher...

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  • Therefore, the present study was designed to study the anti-HF effect of C. wilfordii in an ovariectomized rat model.
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참고문헌 (30)

  1. 1 Kronenberg F 1990 Hot flashes: epidemiology and physiology Ann NY Acad Sci 592 52 86 10.1111/j.1749-6632.1990.tb30316.x 2197954 

  2. 2 Shen W Stearns V 2009 Treatment strategies for hot flushes Expert Opin Pharmacother 10 1133 1144 10.1517/14656560902868217 19405789 

  3. 3 Freedman RR 2001 Physiology of hot flashes Am J Hum Biol 13 453 464 10.1002/ajhb.1077 11400216 

  4. 4 Shanafelt TD Barton DL Adjei AA Loprinzi CL 2002 Pathophysiology and treatment of hot flashes Mayo Clin Proc 77 1207 1218 10.4065/77.11.1207 12440557 

  5. 5 Stearns V Ullmer L López JF Smith Y Isaacs C Hayes DF 2002 Hot flushes Lancet 360 1851 1861 10.1016/S0140-6736(02)11774-0 12480376 

  6. 6 Chambliss KL Shaul PW 2002 Estrogen modulation of endothelial nitric oxide synthase Endocr Rev 23 665 686 10.1210/er.2001-0045 12372846 

  7. 7 Florian M Lu Y Angle M Magder S 2004 Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation Steroids 69 637 645 10.1016/j.steroids.2004.05.016 15465108 

  8. 8 Orshal J Khalil R 2004 Gender, sex hormones, and vascular tone Am J Physiol Regul Integr Comp Physiol 286 R233 R249 10.1152/ajpregu.00338.2003 14707008 

  9. 9 Guo X Razandi M Pedram A Kassab G Levin ER 2005 Estrogen induces vascular wall dilation: mediation through kinase signaling to nitric oxide and estrogen receptors α and β J Biol Chem 280 19704 19710 10.1074/jbc.M501244200 15764600 

  10. 10 Guo X Lu X Ren H Levin ER Kassab GS 2006 Estrogen modulates the mechanical homeostasis of mouse arterial vessels through nitric oxide Am J Physiol Heart Circ Physiol 290 H1788 H1797 10.1152/ajpheart.01070.2005 16306215 

  11. 11 Xing D Nozell S Chen YF Hage F Oparil S 2009 Estrogen and mechanisms of vascular protection Arterioscler Thromb Vasc Biol 29 289 295 10.1161/ATVBAHA.108.182279 2700771 --> 19221203 

  12. 12 Rossouw JE Anderson GL Prentice RL LaCroix AZ Kooperberg C Stefanick ML Jackson RD Beresford SA Howard BV Johnson KC Kotchen JM Ockene J Writing Group for the Women’s Health Initiative Investigators 2002 Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial JAMA 288 321 333 10.1001/jama.288.3.321 12117397 

  13. 13 Carroll DG Kelley KW 2009 Use of antidepressants for management of hot flashes Pharmacotherapy 11 1357 1374 10.1592/phco.29.11.1357 

  14. 14 Stearns V Johnson MD Rae JM Morocho A Novielli A Bhargava P Hayes DF Desta Z Flockhart DA 2003 Active tamoxifen metabolite plasma concentrations after coadministration of tamoxifen and the selective serotonin reuptake inhibitor paroxetine J Natl Cancer Inst 95 1758 1764 10.1093/jnci/djg108 14652237 

  15. 15 Chang A Kwak BY Yi K Kim JS 2012 The effect of herbal extract (EstroG-100) on pre-, peri- and post-menopausal women: a randomized double-blind, placebo-controlled study Phytother Res 26 510 516 10.1002/ptr.3597 21887807 

  16. 16 Lee KH Lee DJ Kim SM Je SH Kim EK Han HS Han IK 2005 Evaluation of effectiveness and safety of natural plants extract (Estromon ® ) on perimenopausal women for 1 year J Korean Soc Menopause 11 16 26 

  17. 17 Freedman RR Krell W 1999 Reduced thermoregulatory null zone in postmenopausal women with hot flashes Am J Obstet Gynecol 181 66 70 10.1016/S0002-9378(99)70437-0 10411797 

  18. 18 Kronenberg F Mallory B Downey JA 1993 Women’s health: new frontiers in rehabilitation medicine Arch Phys Med Rehabil 74 1377 1378 10.1016/0003-9993(93)90096-S 8259908 

  19. 19 Kobayashi T Ushijima O Chen JT Shiraki M Ohta T Kiyoki M 1995 Basal tail skin temperature elevation and augmented response to calcitonin gene-related peptide in ovariectomized rats J Endocrinol 146 431 437 10.1677/joe.0.1460431 7595138 

  20. 20 Berendsen HH Weekers AH Kloosterboer HJ 2001 Effect of tibolone and raloxifene on the tail temperature of oestrogen-deficient rats Eur J Pharmacol 419 47 54 10.1016/S0014-2999(01)00966-9 11348629 

  21. 21 Opas EE Rutledge SJ Vogel RL Rodan GA Schmidt A 2004 Rat tail skin temperature regulation by estrogen, phytoestrogens and tamoxifen Maturitas 48 463 471 10.1016/j.maturitas.2003.11.001 15283940 

  22. 22 Sipe K Leventhal L Burroughs K Cosmi S Johnston GH Deecher DC 2004 Serotonin 2A receptors modulate tail-skin temperature in two rodent models of estrogen deficiency-related thermoregulatory dysfunction Brain Res 1028 191 202 10.1016/j.brainres.2004.09.012 15527744 

  23. 23 Bowe J Li XF Kinsey-Jones J Heyerick A Brain S Milligan S O’Byrne K 2006 The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes J Endocrinol 191 399 405 10.1677/joe.1.06919 1635969 --> 17088409 

  24. 24 Wright BE Katovich MJ 1996 Effect of restraint on druginduced changes in skin and core temperature in biotelemetered rats Pharmacol Biochem Behav 55 219 225 10.1016/S0091-3057(96)00071-8 8951958 

  25. 25 Freedman RR Norton D Woodward S Cornélissen G 1995 Core body temperature and circadian rhythm of hot flashes in menopausal J Clin Endocrinol Metab 80 2354 2358 7629229 

  26. 26 Kobayashi T Tamura M Hayashi M Katsuura Y Tanabe H Ohta T Komoriya K 2000 Elevation of tail skin temperature in ovariectomized rats in relation to menopausal hot flushes Am J Physiol Regul Integr Comp Physiol 278 R863 R869 10749773 

  27. 27 Morito K Hirose T Kinjo J Hirakawa T Okawa M Nohara T Ogawa S Inoue S Muramatsu M Masamune Y 2001 Interaction of Phytoestrogens with Estrogen Receptors α and β Biol Pharm Bull 24 351 356 10.1248/bpb.24.351 11305594 

  28. 28 Kuiper GG Lemmen JG Carlsson B Corton JC Safe SH van der Saag PT van der Burg B Gustafsson JA 1998 Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor β Endocrinology 139 4252 4263 9751507 

  29. 29 Diel P Olff S Schmidt S Michna H 2001 Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7 Planta Med 67 510 514 10.1055/s-2001-16474 11509969 

  30. 30 Jisa E Dornstauder E Ogawa S Inoue S Muramatsu M Jungbauer A 2001 Transcriptional activities of estrogen receptor alpha and beta in yeast properties of raloxifene Biochem Pharmacol 62 953 961 10.1016/S0006-2952(01)00731-6 11543731 

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