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행인(杏仁) 분획물이 Th2 cytokine 발현과 NC/Nga mouse의 아토피 피부염에 미치는 영향
The Effects of Prunus Armeniaca Linne Var Fractions on Th2 Cytokine Expression and Atopic Dermatitis of NC/Nga Mouse 원문보기

大韓韓方小兒科學會誌 = The journal of pediatrics of Korean medicine, v.30 no.4, 2016년, pp.29 - 59  

강기연 (대전대학교 한의과대학 소아과학교실) ,  한재경 (대전대학교 한의과대학 소아과학교실) ,  김윤희 (대전대학교 한의과대학 소아과학교실)

Abstract AI-Helper 아이콘AI-Helper

Objectives PRAL (Prunus armeniaca Linne Var) has been known to suppress allergic reaction. However, the cellular target and its mechanism of action were unclear. This study was designed to investigate the effect of PRAL on RBL-2H3 mast cell, which is PMA-Ionomycin-induced activated in vitro and the ...

주제어

참고문헌 (64)

  1. Lee JH, Kim EH, Cho JB, Kim HY, Suh JM, Ahn KM, Cheong HK, Lee SI. Comparison of prevalence and risk factors of atopic dermatitis by physical examination and questionnaire survey in elementary school children. Asthma Respir Dis. 2011;21(3):186-96. 

  2. Roh SS. Dermatology. Seoul: IBC Inc. 2006:499-527. 

  3. Park BK, Park YC, Jung IC, Kim SH, Choi JJ, Do MH, Kim SY, Jin MR. Gamisasangja-tang suppresses pruritus and atopic skin inflammation in the NC/Nga murine model of atopic dermatitis. J Ethnopharmacol. 2015;65(13):54-60. 

  4. Kim S. A study of IL-31 serum levels in childhood atopic dermatitis. Master's thesis of medicine in Sungkyunkwan university. 2010. 

  5. Stacey RD, Cindy S, Angela H, Janine B, Maryland RF, Scott RP, Harald SH, Mark M, Brandon H, Janet J, Susan B, Sherri M, Joseph LK, Tom B, Pamela S, Dennis LD, Maria D, Francis JG, Luann L, Steven DL, Cosette LC, Kim W, Heather D, Stavros T, Janet K, Rolf K, Zhi C, Don F, Julia PN, Jane AG. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004;5(7):752-60. 

  6. Takaoka A, Arai I, Sugimoto M, Yamaguchi A, Tanaka M, Nakaike S. Expression of IL-31 gene transcripts in NC/Nga mice with atopic dermatitis. Eur J Pharmacol. 2005;5(2):180-1. 

  7. Raap U, Wichmann K, Bruder M, Stander S, Wedi B, Kapp A, Werfel T. Correlation of IL-31 serum levels with severity of atopic dermatitis. J Allergy Clin Immunol. 2008;122(2):421-3. 

  8. Korea Institute of Oriental medicine, The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology. Atopic Dermatitis Korean Medicine Clinical Practice Guideline. Daejeon: Korea Institute of Oriental medicine. 2014:40-67. 

  9. Hanuigwadaehak Bonchohak Pyeonchanwiwonhoe. Bonchohak. Seoul: Younglimsa Publishing Co. 2005:515-6. 

  10. Shin MK. Imsangbonchohak. Seoul: Younglimsa Publishing Co. 1997:177. 

  11. Hwang DR, Kang YS, Kim SS, Kim DH, Shin MK, Son HJ. Studies on the allergic asthma effect of Semen Armeniaceae Amarum. Korea J Herbology. 2003;18(2):201-8. 

  12. Chung W, Jung HJ, Jung SK, Rhee HK. The effects of Armeniacae Arnarum Semen and Platycodi Radix on IL-4, IL-5, IL-6 in asthma model. Korean J Orient Int Med. 2000;21(1):31-8. 

  13. Kim YS, Song CH. Study on the anti-allergic effect of Armeniacae Semen herbal acupuncture solution. Korean J Acupunct. 2007;24(2):151-62. 

  14. Kim O, Kwon KR. The study on acute and subacute toxictiy and sarcoma-180 anti-cancer effects of Armeniacae Amarum Semen herbal-acupuncture (Haeng-In). J Pharmacopuncture. 2002;5(1):61-79. 

  15. Shin HW. The experimental study on the asthma-suppressive & immune response of Armeniacae Amarum Semen herbal-acupuncture at ST36 in OVA-induced asthma mouse. Master's thesis in Korean medicine in Daejeon university. 2006. 

  16. Ju CY, Jung HJ, Jung SK, Rhee HK. Armeniacae Amarum Semen contributes to the chemotaxis of eosinophils and secretion of chemokines in A549 human epithelial cells. Korean J Orient Int Med. 2006;27(1):208-20. 

  17. Choi JY. The analgesic and anti-inflammatory effects of Armenicae Semen: potential role of bradykinin and COX-II-mediated singaling. PhD's thesis of dentistry in Kyunghee university. 2004. 

  18. Kim YH, Joe WA, Jang MJ, Cheon SJ, Sung JY, Jeong YS, Kim YS, Kang BY, Son AR, Lee CE, An BJ, Lee JT. Study on the whitening effect and cosmeceutical activities of Semen Armeniaceae. J Appl Orient Med. 2007;7(1):35-9. 

  19. Kim YH, Lee SM, Cheon SJ, Jang MJ, Jun DH, Choi HJ, Cho WA, Lee JT. Study on cosmeceutical activity of four kinds of Korea herb medicine materials. J Korean Soc Fashion Beauty. 2007;5(4):130-8. 

  20. Kang KY, Han JK, Kim YH. The suppressive effect on Th2 cytokines expression and the signal transduction mechanism in MC/9 mast cells by PRAL. J Pediatr Korean Med. 2014;28(2):23-39. 

  21. Mina Y, Takayo H, Kiyoshi Y, Hisashi T, Miho I, Shigeki T, Masashi D, Akinori A. A novel atopic dermatitis model induced by topical application with dermatophagoides farinae extract in NC/Nga mice. Allergol Int. 2007;56(2):139-48. 

  22. Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Yu SA, Lee SY, Lee JY, Lee HJ, Chang GT, Chai JW, Han YJ, Han JK. Pediatrics of Korean medicine. First volume. Seoul: Euiseongdang Publishing Co. 2015:203-38. 

  23. Cho SI, Kim JH, Chung BY, Ahn IS, Kim HO, Park CW, Lee CH. Quality of life in children and adolescents with atopic dermatitis. Korean J Dermatol. 2011;49(5):415-21. 

  24. Yu SM, Choi IH. The burden of atopic dermatitis on children and their families: quality of life and financial impact in Seoul area. J Korean Orient Ophthalmol Otorhinolaryngol Dermatol. 2010;23(3):122-37. 

  25. Heijden FL, Joost N, Katwijk M, Bos JD, Kapsenberg ML. Serum-IgE-facilitated allergen presentation in atopic disease. J Immunol. 1993;150(8):3643-50. 

  26. Davide A Carla SR, Jay B, Akio M, Massimo G, John J, Shea O, David M. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol. 2003;23(3):147-61. 

  27. Metcalfe DD, Kaliner M, Donlon MA. The mast cell. Crit Rev Immunol. 1981;3(1):23-74. 

  28. Church MK, Levi-Schaffer F. The human mast cell. J Allergy Clin Immunol. 1997;99(2):155-60. 

  29. Abul A, Andrew HL, Shiv P. Cellular & Molecular Immunology. 6th ed. Seoul: Epublic Publishing Co. 2008:451-71. 

  30. Tho D, Roger M, Susan V, Carl W. Immunology (Lippincott's Illustrated Reviews) the 2nd ed. Seoul: Bioscience Publishing Co. 2014:200. 

  31. An SK, Park BD, Won JH, Sung YO, Chun SH. Atopic dermatitis. Seoul: Pacific Publishing Co. 2007:13-82. 

  32. The Korean Academy of Asthma, Allergy and Clinical Immunology. Asthma and Allergic disease. Seoul: Koonja Publshing Co. 2002:13-116. 

  33. Pyun BY. Relationship between atopic dermatitis, wheezing during infancy and asthma development. J Korean Med Assoc. 2007;50(6):533-40. 

  34. Yu JH. Allergic march: progression from atopic dermatitis to asthma. J Asthma Allergy Clin Immunol. 2012;32(3):137-43. 

  35. Heo J. Donguibogam. Seoul: Dobguibogam Publishing Co. 2006:260, 725-7, 1166-7. 

  36. Chae BY. The Korean medical treatment of dermatological. Seoul: Iljoongsa Publishing Co. 1991:40. 

  37. Kim ES, Yoo DY. Protective effect of processed Shengmaisan (SM) on cell damage in UV-exposed HaCaT cell. J Orient Gunecol. 2001;24(2):33-51. 

  38. Moon H, Hwang CY, Hong SH, Hong CH, Kim NK, JO GW, Lim GS. A comparative study on the effects of Saengmaeksan and Saengmaeksan-gamibang on atopic dermatitis in NC/Nga mouse. J Korean Orient Ophthalmol Otorhinolaryngol Dermatol. 2012;25(1):33-54. 

  39. Chung BS, Shin MK. Dohaehyangyangdaesajeon. Seoul: Younglimsa Publishing Co. 2003:625-6. 

  40. Byun SH, Kim HK Jee SY, Lee BW, Kim SC. The role of Armeniacae Amarum Semen in herbal formula. Herbal Formula Sci. 2003;11(2):29-40. 

  41. Cho JH, Chae BY, Kim YB. A literature study of dermatosurgical disease in the Imjeungjinamuian. J Orient Med Surg Ophthalmol Otholaryngol. 2002;15(2):271-88. 

  42. Hwang CH, Yun CS, Song SH, Weon YH, Hwang CY. Effects of Galgeunhaegitang-gamibang administration along with Samhwangseze-gamibang on atopic dermatitis of NC/Nga mice. J Korean Med Ophthalmol Otolaryngol Dermatol. 2008;21(2):1-18. 

  43. Lee SH, Kim JH. The clinical study of atopic dermatitis treated by Bopejungcheuntang (BPJC). J Korean Orient Med. 2000;14(1):137-52. 

  44. Park SN, Jeong SH, Kim YW, Choi OB. Immunomodulation effect of combined herbal extracts on atopic dermatitis in CBA/N mouse. Korean Beauty Soc. 2013;19(1):153-8. 

  45. Kim YH, Lee SY, Kim WI. Experimental study about the pathway of inflammatory allergic reaction of Cheonmaec-tang. J Korean Orient Pediatr. 2010;24(1):93-103. 

  46. Aversa G, Punnonen J, Cocks BG, Malefyt RW, Vega FJ, Zurawski SM, Zurawski G, Vries JE. An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation. J Exp Med. 1994;18(1):2213-8. 

  47. Kim HJ, Kim WS, Park HJ, Moo G, Kim DW, Won JH, Kim YK. Inhibitory effect of Jaeumganghwa-tang on allergic inflammatory reaction. J Korean Orient Int Med. 2004;25(2):174-82. 

  48. Neis MM, Peters B, Dreuw A, Wenzel J, Bieber T, Mauch C, Krieg T, Stanzel S, Heinrich PC, Merk HF, Bosio A, Baron JM, Hermanns HM. Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J Allergy Clin Immunol. 2006;118(4):930-7. 

  49. Sonkoly E, Muller A, Lauerma AI, Pivarcsi A, Soto H, Kemeny L, Alenius H, Dieu-nosjean MC, Meller S, Rieker J, Steinhoff M, Hoffmann TK, Ruzicka T, Zlotnik A, Homey B. IL-31: A new link between T cells and pruritus in atopic skin inflammation. J Allergy Clin Immunol. 2005;117(2):411-77. 

  50. Kim S, Kim HJ, Yang HS, Kim E, Huh IS, Yang JM. IL-31 serum protein and tissue mRNA levels in patients with atopic dermatitis. Ann Dermatol. 2011;23(4):468-743. 

  51. Arai I, Tsuji M, Miyagawa K, Takeda H, Akiyama N, Saito S. Repeated administration of IL-31 upregulates IL-31 receptor A (IL-31RA) in dorsal root ganglia and causes severe itch-associated scratching behaviour in mice. Exp Dermatol. 2015;24(1):75-8. 

  52. Edukulla R, Singh B, Jegga AG, Sontake V, Dillon SR, Madala SK. Th2 cytokines augment IL-31/IL-31RA interactions via STAT6-dependent IL-31RA expression. J Biol Chem. 2015;290(21):13510-20. 

  53. Seoul National University College of Medicine Department of Microbiology. Core hospital microbiology. Seoul: Seoul National University Press. 2006:133. 

  54. Michael K, Zheng-gang L, Ebrahim Z. AP-1 function and regulation. Curr Opin Cell Biol. 1997;9(2):240-6. 

  55. Cheung FY, Wong CK, Ho WY, Hu S, Chen DP, Lam WK. Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: implication for the immunopathogenesis of atopic dermatitis. Int Immunol. 2010;22(6):453-520. 

  56. Christian V, Hiroyuki Y, Konji M. The NC/Nga mouse: a model for atopic dermatitis. Mol Med Today. 2000;5(1):209-10. 

  57. Vestergaard C, Yoneyama H, Murai M, Nakamura K, Tamaki K, Terashima Y, Imai T, Yoshie O, Irimura T, Mizutani H, Matsushima K. Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions. J Clin Invest. 1999;104(8):1097-105. 

  58. Yagi R, Nagai H, Iigo Y, Akimoto T, Arai T, Kubo M. Development of atopic dermatitis-like skin lesions in STAT6-deficient NC/Nga mice. J Immunol. 2002;168(4):2020-7. 

  59. Kim SJ. Immunology. Seoul: Korea Medical Book Publishing Co. 1994:1, 24-36, 65, 154-6, 260-5. 

  60. Dorshkind K, Narayanan R, Landreth KS. Regulatory cells and cytokines involved in primary B lymphocyte production. Adv Exp Med Biol. 1992;323:119-23. 

  61. Bronte V, Wang M, Overwijk WW, Surman DR, Pericle F, Rosenberg SA, Restifo NP. Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells. J Immunol. 1998;161(10):5313-20. 

  62. Young MR, Wright MA, Matthews JP, Malik I, Prechel M. Suppression of T cell proliferation by tumor-induced granulocyte-macrophage progenitor cells producing transforming growth factor-beta and nitric oxide. J Immunol. 1996;156(5):1916-22. 

  63. Angulo I, Heras FG, Garcia-Bustos JF, Gargallo D, Munoz-Fernandez A, Fresno M. Nitric oxide-producing CD11b(+)Ly-6G(Gr-1)(+)CD31(ER-MP12)(+) cells in the spleen of cyclophosphamide-treated mice: implications for T-cell responses in immunosuppressed mice. Blood. 2000;95(1):212-20. 

  64. Kim KD. Functional analysis of CD3- ${\zeta}$ ITAM-mediated T cell activation and apoptosis singnaling. Master's thesis of biotechnology in Yonsei university. 2003. 

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