최소 단어 이상 선택하여야 합니다.
최대 10 단어까지만 선택 가능합니다.
다음과 같은 기능을 한번의 로그인으로 사용 할 수 있습니다.
NTIS 바로가기Journal of sensor science and technology = 센서학회지, v.25 no.5, 2016년, pp.354 - 364
이원일 (성균관대학교 융합의과학과) , 김보영 (성균관대학교 나노과학기술학과) , 손영민 (성균관대학교 융합의과학과) , 김아리 (성균관대학교 나노과학기술학과) , 이내응 (성균관대학교 신소재공학부)
Recently there have been extensive research activities on the development of on-the-spot detection technologies for bacteria from foods due to growing high demand for food safety. In particular, on-the-spot detection devices using biosensors with rapid, highly sensitive and multiplexed sensing capab...
* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.
핵심어 | 질문 | 논문에서 추출한 답변 |
---|---|---|
식품안전 측정 대상물질은 무엇인가? | 식품 안전에 대한 관심이 증가하면서 식품의 안정성을 검사 할 수 있는 식품안전 진단 기술에 대한 수요가 점점 더 증가하고 있다. 측정 대상물질은 농약, 항생제, 첨가물, 중금속, 가공 중의 형성물 등의 화학적 유해물질, 독소, 박테리아, 바이러스 등의 생물학적 유해물질을 포함한다. 현재 식품유해물질 분석방법으로는 식품 안전사고 발생 했을 때 해당 식품의 유해물질 검출을 전문 검사기관에 의뢰하게 되고, 화학적 유해물질의 경우 질량분석기와 같은 고가의 화학분석 장비, 그리고 생물학적 유해물질의 경우 주로 효소면역분석법(ELISA)과 같은 면역분석법, 중합효소연쇄반응(PCR)과 같은 분자진단법 등을 주로 활용하여 분석하게 된다. | |
현재 식품유해물질 분석방법의 한계는 무엇인가? | 이러한 식품유래 유해물질의 분석의 경우 수일 내지 일주 정도의 장시간이 요구 되고 있다. 따라서, 식품안전 사고의 원인을 파악하는데 소요되는 시간과 비용의 문제로 신속한 원인파악 및 대응에는 한계가 있다. 이러한 문제를 해결하기 위해서 현장에서 바로 1-2 시간 내에 신속히 검출할 수 있는 유해물질 검사기술 개발이 필요하다. | |
현재 식품유해물질 분석방법은 어떻게 진행되고 있는가? | 측정 대상물질은 농약, 항생제, 첨가물, 중금속, 가공 중의 형성물 등의 화학적 유해물질, 독소, 박테리아, 바이러스 등의 생물학적 유해물질을 포함한다. 현재 식품유해물질 분석방법으로는 식품 안전사고 발생 했을 때 해당 식품의 유해물질 검출을 전문 검사기관에 의뢰하게 되고, 화학적 유해물질의 경우 질량분석기와 같은 고가의 화학분석 장비, 그리고 생물학적 유해물질의 경우 주로 효소면역분석법(ELISA)과 같은 면역분석법, 중합효소연쇄반응(PCR)과 같은 분자진단법 등을 주로 활용하여 분석하게 된다. 이러한 식품유래 유해물질의 분석의 경우 수일 내지 일주 정도의 장시간이 요구 되고 있다. |
J. M. Bosilevac, M. N. Guerini, D. M. Brichta-Harhay, and M. Koohmaraie, "Microbiological characterization of imported and domestic boneless beef trim used for ground beef", J. Food Prot. Vol. 70, No. 2, pp. 440-449, 2007.
L. Cabedo, L. Picart I Barrot, and A. Teixido I Canelles, "Prevalence of Listeria monocytogenes Salmonella in ready-to-eat food in Catalonia, Spain", J. Food Prot. Vol. 71, No. 4, pp 855-859, 2008.
S. D. Manning, A. S. Motiwala, A. C. Springman, W. Qi, D. W. Lacher, L. M. Ouellette, J. M. Mladonicky, P. Somsel, J. T. Rudrik, S. E. Dietrich, W. Zhang, B. Swaminathan, D. Alland, and T. S. Whittam, "Variation in virulence among clades of Escherichia coli O157:H7 associated with disease outbreaks", Proc. Natl. Acad. Sci. USA, Vol. 105, No. 12, pp 4868-4873, 2008.
J. I. Esteban, B. Oporto, G. Aduriz, R. A. Juste, and A. Hurtado, "A survey of food-borne pathogens in free-range poultry farms", Int. J. Food Microbiol. Vol. 123, No. 1-2, pp 177-182, 2008.
M. Fricker, R. Reissbrodt, and M. Ehling-Schulz, "Evaluation of standard and new chromogenic selective plating media for isolation and identification of Bacillus cereus", Int. J. Food Microbiol. Vol. 121, No. 1, pp 27-34, 2008.
A. Townsend, Encyclopedia analytical science, Academic Press, New York, pp.2057-2066, 1995.
F. Breitling and S. Dubel, Recombinant antibodies, John Wiley and Sons Inc, NewYork, pp 154, 1999.
P. Leonard, S. Hearty, J. Brennan, L. Dunne, J. Quinn, T. Chakraborty, and R. O'Kennedy, "Advances in biosensors for detection of pathogens in food and water", Enzyme Microb. Technol. Vol. 32, No. 1, pp 3-13, 2003.
G. Kohler and C. Milstein, "Continuous cultures of fused cells secreting antibody of predefined specificity", Nature Vol. 256, No. 5517, pp 495-497, 1975.
W. B. Shim, J. G. Choi, Z. Y. Yang, K. H. Lee, M. G. Kim, S. D. Ha, K. S. Kim, K. Y. Kim, C. H. Kim, K. S. Ha, S. A. Eremin, and D. H. Chung, "Production of monoclonal antibody against Listeria monocytogenes and its application to immunochromatography strip test", J. Microbiol. Biotechnol. Vol. 17, No. 7, pp. 1152-1161, 2007.
B. Borck. H. Stryhn, A. K. Ersboll, and K. Pedersen, "Thermophilic Campylobacter spp. In turkey samples: evaluation of two automated enzyme immunoassays and conventional microbiological techniques", J.Appl. Microbiol. Vol. 92, No. 3, pp 574-582, 2002.
R. W. Bennett, "Staphylococcal enterotoxin and its rapid identification in foods by enzyme-linked immunosorbent assay-based methodology", J.Food. Prot. Vol. 68, No. 6. pp 1264-1270, 2005.
R. R. Beumer and E. Brinkman, "Detection of Listeria spp. With a monoclonal antibody-based enzyme-linked immunosorbent assay(ELISA)", Food Microbiol. Vol. 6, No. 3, pp 171-177, 1989.
J. S. Dickson and J. A. Chen, "A fast and accurate detection method of E coli O157H7 in beef", Abstr. Gen. Meet Am. Soc. Microbiol. Vol. 101, pp 573 (2001).
J. A. Hudson, R. J. Lake, P. Scholes, and R. E. McCormick, "Rapid detection of Listeria monocytogenes in ham samples using immunomagnetic separation followed by polymerase chain reaction", J. Appl. Microbiol.Vol. 90, No. 4, pp 614- 621, 2001.
P. T. Feldsine, A. H. Lienau, R. L. Forgey, and R. D. Calhoon, "Visual immunoprecipitate assay (VIP) for Listeria monocytogenes and related Listeria species detection in selected foods: collaborative study", J. AOAC Int. Vol. 80, No. 4, pp 791-805, 1997.
G. M. Matar, P. S. Hayes, W. F. Bibb, and B. Swaminathan, "Listeriolysin O-based latex agglutination test for the rapid detection of Listeria monocytogenes in foods", J. Food Prot. Vol. 60, No. 8, pp 1019-1151, 1997.
A. Rasooly and R. S. Rasooly, "Detection and analysis of Staphylococcal enterotoxin A in food by Western immunoblotting", Int. J. Food Microbiol. Vol. 41, No. 3, pp 205- 212, 1998.
J. H. Meng and M. P. Doyle, "Introduction. Microbiological food safety", Microbes Infect. Vol. 4, No. 4, pp 395-397, 2002.
S. S. Iqbal, M. W. Mayo, J. G. Bruno, B. V. Bronk, C. A. Batt, and J. P. Chambers, Biosens. Bioelectron. Vol. 15, No. 11-12, pp 549-578, 2000.
C. A. Batt, "Food pathogen detection", Science Vol. 316, No. 5831, pp 1579-1580, 2007.
A. Touron, T. Berthe, and F. Petit, "Detection of Salmonella in environmental water and sediment by a nested-multiplex polymerase chain reaction assay", Res. Microbiol. Vol. 156, No, 4, pp 541-553, 2005.
P. T. Desai, K. W. Marie, and C. W. Bart, "Solid-phase capture of pathogenic bacteria by using gangliosides and detection with real-time PCR", Appl. Environ. Microbiol. Vol. 74, No. 7, pp 2254-2258, 2008.
A. Jofr'e, B. Martin, M. Garriga, and T. Aymerich, "Simultaneous detection of Listeria monocytogenes and Salmonella by multiplex PCR in cooked ham", Food Microbiol. Vol. 22, No, 1, pp 109-115, 2005.
A. K Deisingh, and M. Thompson, "Strategies for the detection of Escherichia coli O157:H7 in foods", J. Appl. Microbiol. Vol. 96, No. 3, pp 419-429, 2004.
I. H. Cho, A. Bhunia, and J. Irudayarai, "Rapid pathogen detection by lateral-flow immunochromatographic assay with gold nanoparticle-assisted enzyme signal amplification", J. Food Microbiol. Vol. 206, pp 60-66, 2015.
A. Ahmed, J. V. Rushworth, N. A. Hirst, and P. A. Millner, "Biosensors for whole-cell bacterial detection", Clin. Microbiol. Rev. Vol. 27, No. 3, pp 631-646, 2014.
LC Clark, R. Wolf, D. Granger, and Z. Taylor, "Continuous recording of blood oxygen tensions by polarography", J. Appl. Physiol. Vol. 6, No. 3, pp 189-193, 1953.
V. Velusamy, K. Arshak, O. Korostynska, K. Oliwa, and C. Adley, "An overview of foodborne pathogen detection: in the perspective of biosensors", Biotechnol. Adv. Vol. 28, No. 2, pp 232-254, 2010.
I. Palchetti, and M. Mascini, "Electroanalytical biosensors and their potential for food pathogen and toxin detection", Anal. Bioanal. Chem. Vol. 391, No. 2, pp 455-471, 2008.
AB Esteban-Fernandez, M. Pedrero, S. Campuzano, V. Escamilla-Gomez, and J. M. Pingarron, "Sensitive and rapid amperometric magnetoimmunosensor for the determination of Staphylococcus aureus", Anal. Bioanal. Chem. Vol. 403, No. 4, pp 917-925, 2012.
C. Ercole, M. D. Gallo, L. Mosiello, S. Baccella, and A. Lepidi, "Escherichia coli detection in vegetable food by a potentiometric biosensor", Sens. Actuator B-Chem. Vol. 91, No. 1-3, pp 163-168, 2003.
J. S. Daniels, and N. Pourmand, "Label-free impedance biosensors: opportunities and challenges", Electroanalysis Vol. 19, No, 12, pp 1239-1257, 2007.
F. Tan, P. H. M. Leung, Z. Liu, L. Xiao, W. Ye, X. Zhang, L. Yi, and M. Yang, "A PDMS microfluidic impedance immunosensor for E. coli O157:H7 and Staphylococcus aureus detection via antibody-immobilized nanoporous membrane", Sens. Actuators B-Chem. Vol. 159, No. 1, pp 328-335, 2011.
Y. Wang, Z. Ye, and Y. Ying, "New trends in impedimetric biosensors for the detection of foodborne pathogenic bacteria", Sensors Vol. 12, No, 3, pp 3449-3471, 2012.
Y. Li, L. Fang, P. Cheng, J. Deng, L. Jiang, H. Huang, and J. Zheng, "An electrochemical immunosensor for sensitive detection of Escherichia coli O157:H7 using C60 based biocompatible platform and enzyme functionalized Pt nanochains tracing tag", Biosens. Bioelectron. Vol. 49, pp 485-491, 2013.
M. Varshney, L. Yang, X. L. Su, and Y. Li, "Magnetic nanoparticle-antibody conjugates for the separation of Escherichia coli O157:H7 in ground beef", J. Food Prot., Vol. 68, No. 9, pp 1804-1811, 2005.
S. Chemburu, E. Wilkins, and I. Abdel-Hamid, "Detection of pathogenic bacteria in food samples using highly-dispersed carbon particles", Biosens. Bioelectron. Vol. 21, No. 3, pp 491-499, 2005.
G. Zhao, F. Xing, and S. Deng, "A disposable amperometric enzyme immunosensor for rapid detection of Vibrio parahaemolyticus in food based on agarose/Nano-Au membrane and screen-printed electrode", Electrochem. Commun. Vol. 9, No. 6, pp 1263-1268, 2007.
M. Rochelet. S. Solanas, L. Betelli, B. Chantemesse, F. Vienney, and A. Hartmann, "Rapid amperometric detection of Escherichia coli in wastewater by measuring $\beta$ -D glucuronidase activity with disposable carbon sensors", Anal. Chim. Acta Vol. 892, pp 160-166, 2015.
O. Laczka, J. M. Maesa, N. Godino, J. del Campo, M. Fougt-Hansen, J. P. Kutter, D. Snakenborg, F. X. Munoz- Pascual, and E. Baldrich, "Improved bacteria detection by coupling magneto-immunocapture and amperometry at flow-channel microband electrodes", Biosens. Bioelectron. Vol. 26, No. 8, pp 3633-3640, 2011.
G. A. Zelada-Guillen, S. V. Bhosale, J. Riu, and F. X. Rius, "Real-time potentiometric detection of bacteria in complex samples", Anal. Chem. Vol. 82, No. 22, pp 9254-9260, 2010.
M. Barreios dos Santos, J. P. Aqusil, B. Prieto-Simon, C. Sporer, V. Teixeira, and J. Samitier, "Highly sensitive detection of pathogen Escherichia coli O157:H7 by electrochemical impedance spectroscopy", Biosens. Bioelectron. Vol. 45, pp 174-180, 2013.
C. K. Joung, H. N. Kim, M. C. Lim, T. J. Jeon, H. Y. Kim, and Y. R. Kim, "A nanoporous membrane-based impedimetric immunosensor for label-free detection of pathogenic bacteria in whole milk", Biosens. Bioelectron. Vol. 44, pp 210-215, 2013.
J. C. Jokerst, J. M. Emory, and C. S. Henry, "Advances in microfluidics for environmental analysis", Analyst Vol. 137, No. 1, pp 24-34, 2012.
R. Comparelli, M. L. Curri, P. D. Cozzoli, and M. Striccoli, Nanotechnologies for the Life Sciences: Nanomaterials for Biosensors, Wiley-VCH, Weinheim, pp 123-174, 2007.
S. M. Yoo, and S. Y. Lee, "Optical biosensors for the detection of pathogenic microorganisms", Trends Biotechnol. Vol. 34, No. 1, pp 7-25, 2016.
S. Alhogail, G. A. Suaifan, and M. Zourob, "Rapid colorimetric sensing platform for the detection of Listeria monocytogenes foodborne pathogen", Biosens. Bioelectron. Vol. 86, pp 1061-1066, 2016.
P. J. Vikesland, and K. R. Wigginton, "Nanomaterial enabled biosensors for pathogen monitoring - A review", Environ. Sci. Technol. Vol. 44, No. 10, pp 3656-3669, 2010.
I.-H. Cho, L. Mauer, and J. Irudayarai, "In-situ fluorescent immunomagnetic multiplex detection of foodborne pathogens in very low numbers", Biosens. Bioelectron. Vol. 57, pp 143-148, 2014.
Y. Wang, Z. Ye, C. Si, and Y. Ying, "Monitoring of Escherichia coli O157:H7 in food samples using lectin based surface Plasmon resonance", Food Chem. Vol. 136, No. 3- 4, pp 1303-1308, 2013.
C. Pohlmann, I. Dieser, and M. Sprinzi, "A lateral flow assay for identification of Escherichia coli by ribosomal RNA hybridization", Analyst, Vol. 139, No. 5, pp 1063- 1071, 2014.
J. C. Jokerst, J. A. Adkins, B. Bisha, M. M. Mentele, L. D. Goodridge, and C. S. Henry, "Development of a paperbased analytical device for colorimetric detection of select foodborne pathogens", Anal. Chem. Vol. 84, No. 6, pp 2900-2907, 2012.
S. M. Hossain, C. Ozimok, S. D. Aquirre, M. M. Ali, Y. Li, and J. D. Brennan, "Multiplexed paper test strip for quantitative bacterial detection", Anal. Bioanal. Chem. Vol. 403, No. 6, pp 1567-1576, 2012.
J. G. Bruno, "Application of DNA aptamers and quantum dots to lateral flow test strips for detection of Foodborne pathogens with improved sensitivity versus colloidal gold", Pathogens, Vol. 3, No. 2, pp 341-355, 2014.
K. Tram, P. Kanda, B. J. Salena, S. Huan, and Y. Li, "Translating bacterial detection by DNAzymes into a litmus test", Angew. Chem. Int. Ed. Engl. Vol. 53, No. 47, pp 12799- 12802, 2014.
M. A. Hahn, P. C. Keng, and T. D. Krauss, "Flow cytometric analysis to detect pathogens in bacterial cell mixtures using semiconductor quantum dots", Anal. Chem. Vol. 80, No. 3, pp 864-872, 2008.
S. Ko, and S. A. Grant, "A novel FRET-based optical fiber biosensor for rapid detection of Salmonella typhimurium", Biosens. Bioelectron. Vol. 21, No. 7, pp 1283-1290, 2006.
Y. Song, W. Li, Y. Duan, Z. Li, and L. Deng, "Nicking enzyme-assisted biosensor for Salmonella enteritidis detection based on fluorescence resonance energy transfer", Biosens. Bioelectron. Vol. 55, pp 400-404, 2014.
Y. Wang, W. Knoll, and J. Dostalek, "Bacterial pathogen surface Plasmon resonance biosensor advanced by long range surface plasmons and magnetic nanoparticle assays", Anal. Chem. Vol. 84, No. 19, pp 8345-8350, 2012.
O. Torun, I. Hakki Boyaci, E. Temur, and U. Tamer, "Comparison of sensing strategies in SPR biosensor for rapid and sensitive enumeration of bacteria", Biosens. Bioelectron. Vol. 37, No. 1, pp 53-60, 2012.
H. Zhou, D. Yang, N. P. Ivleva, N. E. Mircescu, R. Niessner, and C. Haisch, "SERS detection of bacteria in water by in situ coating with Ag nanoparticles", Anal. Chem. Vol. 86, No. 3, pp 1525-1533, 2014.
B. J. Yakes, R. J. Lipert, J. P. Bannantine, and M. D. Porter, "Impact of protein shedding on detection of Mycobacterium avium subsp. paratuberculosis by a whole-cell immunoassay incorporating surface-enhanced raman scattering", Clin. Vaccine Immunol. Vol. 15, No. 2, pp 235-242, 2008.
E. Temur, A. Zengin, I. Hakki Boyaci, F. C. Dudak, H. Torul, and U. Tamer, Anal. Chem. Vol. 84, No. 24, pp 10600-10606, 2012.
J. M song, and T. Vo-Dinh, "Miniature biochip system for detection of Escherichia coli O157:H7 based on antibodyimmobilized capillary reactors and enzyme-linked immunosorbent assay", Anal. Chim. Acta, Vol. 507, No. 1, pp 115-121, 2004.
K. E. Sapsford, C. Bradburne, J. B. Delehanty, and I. L. Medintz, "Sensors for detecting biological agents", Mater. Today Vol. 11, No. 3, pp 38-49, 2008.
A. Huang, Z. Qiu, M. Jin, Z. Shen, Z. Chen, X. Wang, and J. W. Li, "High-throughput detection of food-borne pathogenic bacteria using oligonucleotide microarray with quantum dots as fluorescent labels", Int. J. Food Microbiol. Vol. 185, pp 27-32, 2013.
S. Tombelli, M. Minunni, and M. Mascini, "Aptamersbased assays for diagnostics, environmental and food analysis", Biomol. Eng. Vol. 24, No. 2, pp 191-200, 2007.
T. Mairal, V. C. Ozlp, P. Lozano Sanchez, M. Mir, I. Katakis, and C. K. O'Sullivan, "Aptamers: molecular tools for analytical applications", Anal. Bioanal. Chem. Vol. 390, No. 4, pp 989-1007, 2008.
M. Famulok, G. Mayer, and M. Blind, "Nucleic acid aptamers- from selection in vitro to applications in vivo", Acc. Chem. Res. Vol. 33, No. 9, pp 591-599, 2000.
M. Blazkova, M. Koets, P. Rauch, and A. V. Amerongen, "Development of a nucleic acid lateral flow immunoassay for simultaneous detection of Listeria spp. and Listeriamonocytogenes in food", Eur. Food Res. Technol. Vol. 229, No. 6, 867-874, 2009.
Y. H. Lin, S. H. Chen, Y. C. Chuang, Y. C. Lu, T. Y. Shen, C. A. Chang, and C. S. Lin, "Disposable amperometric immunosensing strips fabricated by Au nanoparticles-modified screen-printed carbon electrodes for the detection of foodborne pathogen Escherichia coli O157:H7", Biosens. Bioelectron. Vol. 23, No. 12, pp 1832-1837, 2008.
W. Wu, S. Zhao, Y. Mao, Z. Fang, X. Lu, and L. Zeng, "A sensitive lateral flow biosensor for Escherichia coli O157:H7 detection based on aptamer mediated strand displacement amplification", Anal. Chim. Acta Vol. 861, pp 62-68, 2014.
W. Lee, D. Kwon, W. Choi, G. Y. Jung, A. K. Au, A. Folch, and S, Jeon, "3D-printed microfluidic device for the detection of pathogenic bacteria using size-based separation in helical channel with trapezoid cross-section", Sci. Rep. Vol. 5, pp 7717, 2015.
T. H. Kim, J. Park, C. J. Kim, and Y. K. Cho, "Fully integrated lab-on-a-disc for nucleic acid analysis of food-borne pathogens", Anal. Chem. Vol. 86, No. 8, pp 3841-3848, 2014.
A. A. Sayad, F. Ibrahim, S. M. Uddin, K. X. Pei, M. S. Mohktar, M. Madou, and K. L. Thong, "A microfluidic labon- a-disc integrated loop mediated isothermal amplification for foodborne athogen detection", Sens. Actuator B-Chem. Vol. 227, pp 600-609, 2016.
H. Zhu, U. Sikora, and A. Ozcan, "Quantum dot enabled detection of Escherichia coli using a cell-phone", Analyst Vol. 137, No. 11, pp 2541-2544, 2012.
P. Liang, T. S. Park, and J. Y. Yoon,"Rapid and reagentless detection of microbial contamination within meat utilizing a smartphone-based biosensor", Sci. Rep. Vol. 4, pp 5953, 2014.
S. Seo, S. Kim, J. Jeon, J. Kim, H. Kim, J. Cho, W. Lee, and S. Paek, "Food contamination monitoring via internet of things, exemplified by using pocket-sized immunosensor as terminal unit", Sens. Actuator B-Chem. Vol. 233, pp 148-156, 2016.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.