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Dental anesthesia for patients with allergic reactions to lidocaine: two case reports 원문보기

Journal of dental anesthesia and pain medicine, v.16 no.3, 2016년, pp.209 - 212  

Lee, Jiseon (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University) ,  Lee, Ju-Young (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University) ,  Kim, Hyun Jeong (Department of Dental Anesthesiology, Dental Research Institute, School of Dentistry, Seoul National University) ,  Seo, Kwang-Suk (Department of Dental Anesthesiology, Dental Research Institute, School of Dentistry, Seoul National University)

Abstract AI-Helper 아이콘AI-Helper

Lidocaine, a local anesthetic commonly used in dental treatments, is capable of causing allergies or adverse effects similar to allergic reactions. However, the frequency of such occurrences in actual clinical settings is very rare, and even clinical tests on patients with known allergies to local a...

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제안 방법

  • 5 mg Ativan. Afterward, the patient appeared to be more stable, but began showing symptoms of shaking her chin and one of her arms, for which 0.5 ampule of DemerolTM was administered, after which her condition began to improve. The testing was completed within 20 min and the patient was discharged after a 5 h observation period.
  • Skin prick testing was performed using lidocaine, procaine, bupivacaine, mepivacaine, chirocaine (levobupivacaine), ropivacaine, and articaine, and the patient tested positive to lidocaine, ropivacaine, and articaine (Fig. 1). Among the drugs to which she had tested negative, lidocaine, procaine, mepivacaine, and bupivacaine were used for a skin test, in which a positive reaction was seen only with lidocaine.
  • The objective of the present case report was to examine two cases of positive skin allergy tests performed as a result of the occurrence of adverse effects associated with the use of lidocaine as local anesthesia, and to report on dental treatments under such circumstances, along with a literature review.

대상 데이터

  • A 54-year-old female patient, weighing 77 kg, experienced various symptoms such as clouding of consciousness, hearing impairment, and chills during dental treatment for periodontal disease using a local anesthetic. Under the assumption that these adverse effects were attributable to the use of lidocaine, the patient was transferred to the Department of Allergy to determine whether local anesthesia with bupivacaine would be possible.
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참고문헌 (10)

  1. 1 Batinac T Sotosek Tokmadzic V Peharda V Brajac I Adverse reactions and alleged allergy to local anesthetics: Analysis of 331 patients J Dermatol 2013 40 522 527 23682746 

  2. 2 Finder RL Moore PA Adverse drug reactions to local anesthesia Dent Clin North Am 2002 46 747 757 12436829 

  3. 3 Speca SJ Boynes SG Cuddy MA Allergic reactions to local anesthetic formulations Dent Clin North Am 2010 54 655 664 20831929 

  4. 4 Fisher MM Bowey CJ Alleged allergy to local anaesthetics Anaesth Intensive Care 1997 25 611 614 9452840 

  5. 5 Ping B Kiattavorncharoen S Durward C Im P Saengsirinavin C Wongsirichat N Hemodynamic changes associated with a novel concentration of lidocaine hcl for impacted lower third molar surgery J Dent Anesth Pain Med 2015 15 121 128 

  6. 6 Noormalin A Shahnaz M Rosmilah M Mujahid SH Gendeh BS Ige-mediated hypersensitivity reaction to lignocaine - a case report Trop Biomed 2005 22 179 183 16883285 

  7. 7 González-Delgado P Anton R Soriano V Zapater P Niveiro E Cross-reactivity among amide-type local anesthetics in a case of allergy to mepivacaine J Investig Allergol Clin Immunol 2006 16 311 313 

  8. 8 Grzanka A Wasilewska I Sliwczynska M Misiolek H Hypersensitivity lo local anesthetics Anaesthesiol Intensive Ther 2016 48 128 134 26977853 

  9. 9 Thyssen JP Menne T Elberling J Plaschke P Johansen JD Hypersensitivity to local anaesthetics--update and proposal of evaluation algorithm Contact Dermatitis 2008 59 69 78 18759873 

  10. 10 Fellinger C Wantke F Hemmer W Sesztak-Greinecker G Wohrl S The rare case of a probably true ige-mediated allergy to local anaesthetics Case Rep Med 2013 2013 201586 

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