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NTIS 바로가기대한한방내과학회지 = The journal of internal Korean medicine, v.38 no.6, 2017년, pp.1021 - 1034
강아미 (동국대학교 한의과대학 비계내과학교실) , 임성우 (동국대학교 한의과대학 비계내과학교실)
Objectives: The aim of this study was to investigate the effects of Gaejigayonggolmoryo-tang (GYT) on ulcerative colitis induced by dextran sodium sulfate (DSS) in mice. Methods: Colitis was induced by free drinking of 5% DSS in six-week-old male ICR mice. The experimental groups were the sample gro...
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핵심어 | 질문 | 논문에서 추출한 답변 |
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궤양성 대장염이란 무엇인가? | 궤양성 대장염은 대장점막을 침범하는 원인미상의 만성 염증성 장 질환으로, 혈변과 설사가 주 증상과 함께 점액변, 이급후중, 변실금, 복통 등이 나타나기도 하며 피로감, 식욕부진, 체중감소 등 전신 증상이 동반되는 만성적 경과가 특징인 질환이다1. | |
대장에 존재하는 술잔세포로 생산된 점액의 역할은 무엇인가? | 조직학적으로는 대장에 존재하는 술잔세포가 대장내의 점액을 생산하는 주된 세포로서, 생산된 점액은 점막을 보호하는 중요한 역할을 한다. DSS로 대장염이 유도된 Control group에서는 창자샘의 많은 부분이 침식되어 없어지면서 그 벽을 이루던 술잔세포를 비롯한 여러 세포가 없어졌으며, 상피탈락현상 그리고 염증세포의 침윤 등 심하게 손상된 모습을 나타내었다. | |
궤양성 대장염의 치료에는 어떤 방법이 있는가? | 57명에 이른 것으로 보고되었다2. 치료는 식사요법, 약물요법, 백혈구 제거요법, 외과치료 등이 있으나 일반적으로 환자의 영양상태 개선과 함께 염증 매개 억제와 숙주의 방어기전을 증가 시키는 악물 치료가 유지 된다3. |
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