$\require{mediawiki-texvc}$

연합인증

연합인증 가입 기관의 연구자들은 소속기관의 인증정보(ID와 암호)를 이용해 다른 대학, 연구기관, 서비스 공급자의 다양한 온라인 자원과 연구 데이터를 이용할 수 있습니다.

이는 여행자가 자국에서 발행 받은 여권으로 세계 각국을 자유롭게 여행할 수 있는 것과 같습니다.

연합인증으로 이용이 가능한 서비스는 NTIS, DataON, Edison, Kafe, Webinar 등이 있습니다.

한번의 인증절차만으로 연합인증 가입 서비스에 추가 로그인 없이 이용이 가능합니다.

다만, 연합인증을 위해서는 최초 1회만 인증 절차가 필요합니다. (회원이 아닐 경우 회원 가입이 필요합니다.)

연합인증 절차는 다음과 같습니다.

최초이용시에는
ScienceON에 로그인 → 연합인증 서비스 접속 → 로그인 (본인 확인 또는 회원가입) → 서비스 이용

그 이후에는
ScienceON 로그인 → 연합인증 서비스 접속 → 서비스 이용

연합인증을 활용하시면 KISTI가 제공하는 다양한 서비스를 편리하게 이용하실 수 있습니다.

Clinical management of suspected intracranial meningioma in three dogs with pulsed high-dose hydroxyurea 원문보기

Korean journal of veterinary research = 대한수의학회지, v.58 no.2, 2018년, pp.103 - 106  

Cho, Jae-Geum (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ,  Song, Kun-Ho (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University) ,  Seo, Kyoung-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chungnam National University)

Abstract AI-Helper 아이콘AI-Helper

Three aged dogs, all over 15 years old, with multiple seizure events and various neurologic signs such as head turn and ataxia were brought to the referring hospital. Two cases were tentatively diagnosed with intracranial meningioma based on magnetic resonance imaging, and one case was histopatholog...

주제어

AI 본문요약
AI-Helper 아이콘 AI-Helper

* AI 자동 식별 결과로 적합하지 않은 문장이 있을 수 있으니, 이용에 유의하시기 바랍니다.

제안 방법

  • 25 mg/kg/day) in all cases, and the HU was then tapered to 25 to 30 mg/kg once a day with the improvement of clinical signs. All three patients were stable while being treated with pulse therapy of highdose HU and were well managed for 4, 10, and 15 months, respectively. In Case 2, though the patient intermittently displayed mild neurological deficits, such as dullness and head tilt in the course of treatment, the dog’s general condition was stable, and he survived for 10 months.
  • When seizures or other neurologic signs occasionally recurred, the high-dose HU was again administered and then tapered back to the traditional dose (20–30 mg/kg/day), and the dog managed well with the adjustments. She survived for 10 months and was then euthanized due to uncontrollable neurological dysfunctions, and the diagnosis of an inflamed and necrotic intracranial meningioma was confirmed by histopathological evaluation of biopsy samples taken at necropsy (Fig. 3).

대상 데이터

  • 4 cm) with contrast enhancement in right frontal lobe and edematous lesion and compression of lateral ventricle in T2-weighted transverse image (A) and T1-weighted transverse image (B). A 16-year-old castrated male Yorkshire Terrier (Case 3) after the second cluster seizure episodes. Mass (1.
  • A 16-year-old castrated male Yorkshire Terrier (Case 3) was presented after a second episode of cluster seizures, and the owner reported an abrupt onset of signs. On initial screening, hepatic neoplasia (suspected biliary adenoma) was identified, and MRI of the brain revealed a mass (1.
  • A 16-year-old intact female Shih Tzu (Case 2) in status epilepticus and with a right-sided head turn was referred and the clinical signs had been worsening over the previous 2 years according to the owner. Along with multiple seizure episodes, a variety of neurologic signs, such as altered mentation, head tilt, and nystagmus, were observed in this case.
  • 3. A 16-year-old intact female Shit Tzu (Case 2). Brain tissues obtained at necropsy representing inflamed and partially necrotic meningioma.
  • 1. A 19-year-old female Maltese (Case 1) with several generalized tonic-clonic seizures. Homogenous contrast mass (2.
본문요약 정보가 도움이 되었나요?

참고문헌 (11)

  1. Adamo PF, Forrest L, Dubielzig R. Canine and feline meningiomas: diagnosis, treatment, and prognosis. Compend Contin Educ Vet 2004, 26, 951-966. 

  2. Dickinson PJ. Advances in diagnostic and treatment modalities for intracranial tumors. J Vet Intern Med 2014, 28, 1165-1185. 

  3. Ettinger SJ, Feldman EC. Neurologic disease. In: Textbook of Veterinary Internal Medicine. 8th ed. pp. 1363-1464, Saunders, St. Louis, 2017. 

  4. Horta RS, Martins BC, Martins GC, Marcinowska A. Advances in diagnosis and management of intracranial and spinal meningiomas in dogs and cats. Rev Port Cienc Vet 2015, 110, 172-180. 

  5. LeCouteur RA, Withrow SJ. Tumors of the nervous system. In: Withrow and MacEwen's Small Animal Clinical Oncology. 4th ed. pp. 583-589, Elsevier Saunders, St. Louis, 2007. 

  6. Motta L, Mandara MT, Skerritt GC. Canine and feline intracranial meningiomas: an updated review. Vet J 2012, 192, 153-165. 

  7. Newton HB. Hydroxyurea chemotherapy in the treatment of meningiomas. Neurosurg Focus 2007, 23, E11. 

  8. Schrell UMH, Rittig MG, Anders M, Koch UH, Marschalek R, Kiesewetter F, Fahlbusch R. Hydroxyurea for treatment of unresectable and recurrent meningiomas. II. Decrease in the size of meningiomas in patients treated with hydroxyurea. J Neurosurg 1997, 86, 840-844. 

  9. Sessums K, Mariani C. Intracranial meningioma in dogs and cats: a comparative review. Compend Contin Educ Vet 2009, 31, 330-339. 

  10. Sturges BK, Dickinson PJ, Bollen AW, Koblik PD, Kass PH, Kortz GD, Vernau KM, Knipe MF, LeCouteur RA, Higgins RJ. Magnetic resonance imaging and histological classification of intracranial meningiomas in 112 dogs. J Vet Intern Med 2008, 22, 586-595. 

  11. Tamura S, Tamura Y, Ohoka A, Hasegawa T, Uchida K. A canine case of skull base meningioma treated with hydroxyurea. J Vet Med Sci 2007, 69, 1313-1315. 

저자의 다른 논문 :

관련 콘텐츠

오픈액세스(OA) 유형

BRONZE

출판사/학술단체 등이 한시적으로 특별한 프로모션 또는 일정기간 경과 후 접근을 허용하여, 출판사/학술단체 등의 사이트에서 이용 가능한 논문

이 논문과 함께 이용한 콘텐츠

저작권 관리 안내
섹션별 컨텐츠 바로가기

AI-Helper ※ AI-Helper는 오픈소스 모델을 사용합니다.

AI-Helper 아이콘
AI-Helper
안녕하세요, AI-Helper입니다. 좌측 "선택된 텍스트"에서 텍스트를 선택하여 요약, 번역, 용어설명을 실행하세요.
※ AI-Helper는 부적절한 답변을 할 수 있습니다.

선택된 텍스트

맨위로